Candidalysin is a fungal peptide toxin critical for mucosal infection DL Moyes, D Wilson, JP Richardson, S Mogavero, SX Tang, J Wernecke, ... Nature 532 (7597), 64-68, 2016 | 849 | 2016 |
Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor J Ho, X Yang, SA Nikou, N Kichik, A Donkin, NO Ponde, JP Richardson, ... Nature communications 10 (1), 2297, 2019 | 139 | 2019 |
Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor T Tarragó, N Kichik, B Claasen, R Prades, M Teixidó, E Giralt Bioorganic & medicinal chemistry 16 (15), 7516-7524, 2008 | 133 | 2008 |
The natural product berberine is a human prolyl oligopeptidase inhibitor T Tarrago, N Kichik, J Seguí, E Giralt ChemMedChem: Chemistry Enabling Drug Discovery 2 (3), 354-359, 2007 | 95 | 2007 |
Candida albicans Interactions with Mucosal Surfaces during Health and Disease SA Nikou, N Kichik, R Brown, NO Ponde, J Ho, JR Naglik, JP Richardson Pathogens 8 (2), 53, 2019 | 86 | 2019 |
Processing of Candida albicans Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence JP Richardson, S Mogavero, DL Moyes, M Blagojevic, T Krüger, ... MBio 9 (1), 10.1128/mbio. 02178-17, 2018 | 86 | 2018 |
Candida albicans and candidalysin in inflammatory disorders and cancer J Ho, G Camilli, JS Griffiths, JP Richardson, N Kichik, JR Naglik Immunology 162 (1), 11-16, 2021 | 69 | 2021 |
NMR analysis of G-protein βγ subunit complexes reveals a dynamic Gα-Gβγ subunit interface and multiple protein recognition modes AV Smrcka, N Kichik, T Tarragó, M Burroughs, MS Park, NK Itoga, ... Proceedings of the National Academy of Sciences 107 (2), 639-644, 2010 | 34 | 2010 |
Candidalysins are a new family of cytolytic fungal peptide toxins JP Richardson, R Brown, N Kichik, S Lee, E Priest, S Mogavero, ... MBio 13 (1), e03510-21, 2022 | 27 | 2022 |
Albumin Neutralizes Hydrophobic Toxins and Modulates Candida albicans Pathogenicity S Austermeier, M Pekmezović, P Porschitz, S Lee, N Kichik, DL Moyes, ... MBio 12 (3), 10.1128/mbio. 00531-21, 2021 | 25 | 2021 |
15N Relaxation NMR Studies of Prolyl Oligopeptidase, an 80 kDa Enzyme, Reveal a Pre‐existing Equilibrium between Different Conformational States N Kichik, T Tarragó, B Claasen, M Gairí, O Millet, E Giralt ChemBioChem 12 (18), 2737-2739, 2011 | 25 | 2011 |
Processing of Candida albicans Ece1p is critical for candidalysin maturation and fungal virulence. mBio 9: e02178-17 JP Richardson, S Mogavero, DL Moyes, M Blagojevic, T Kruger, ... | 19 | 2018 |
Simultaneous 19F NMR Screening of Prolyl Oligopeptidase and Dipeptidyl Peptidase IV Inhibitors N Kichik, T Tarragó, E Giralt ChemBioChem 11 (8), 1115-1119, 2010 | 17 | 2010 |
Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis Y Wu, S Du, LH Bimler, KE Mauk, L Lortal, N Kichik, JS Griffiths, R Osicka, ... Cell reports 42 (10), 2023 | 16 | 2023 |
A cost‐effective labeling strategy for the NMR study of large proteins: selective 15N‐labeling of the tryptophan side chains of prolyl oligopeptidase T Tarragó, B Claasen, N Kichik, RA Rodriguez‐Mias, M Gairí, E Giralt ChemBioChem 10 (17), 2736-2739, 2009 | 16 | 2009 |
Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor. Nat Commun 10: 2297 J Ho, X Yang, SA Nikou, N Kichik, A Donkin, NO Ponde, JP Richardson, ... | 12 | 2019 |
NMR analysis of G-protein subunit complexes reveals a dynamic G-G subunit interface and multiple protein recognition modes AV Smrcka, N Kichik, T Tarragó, M Burroughs, MS Park, NK Itoga, ... Proceedings of the National Academy of Science 107, 639-644, 2009 | 3 | 2009 |
In Vitro Biophysical Characterization of Candidalysin: A Fungal Peptide Toxin S Lee, N Kichik, OW Hepworth, JP Richardson, JR Naglik Candida Species: Methods and Protocols, 163-176, 2022 | 2 | 2022 |
NMR analysis of G-protein βγ subunit complexes reveals a dynamic Gα-Gβγ subunit interface and multiple protein recognition modes AV Smrcka, N Kichik, T TarragÃ, M Burroughs, MS Park, NK Itoga, ... Proceedings of the National Academy of Sciences of the United States of America, 2010 | 1 | 2010 |
MECHANISMS FOR INHIBITION OF GBETA/GAMMA SIGNALING BY PROTEINS, PEPTIDES AND SMALL MOLECULES AV Smrcka, S Malik, P Seneviratne, A Dessal, N Kichik, T Tarrago, E Giralt JOURNAL OF PHYSIOLOGICAL SCIENCES 59, 56-56, 2009 | 1 | 2009 |