| Comparison of Pharmacological Properties between the Kappa Opioid Receptor Agonist Nalfurafine and 42B, Its 3-Dehydroxy Analogue: Disconnect between in Vitro Agonist … D Cao, P Huang, YT Chiu, C Chen, H Wang, M Li, Y Zheng, FJ Ehlert, ... ACS chemical neuroscience 11 (19), 3036-3050, 2020 | 21 | 2020 |
| Application of bivalent bioisostere concept on design and discovery of potent opioid receptor modulators H Ma, S Obeng, H Wang, Y Zheng, M Li, AM Jali, DL Stevens, WL Dewey, ... Journal of Medicinal Chemistry 62 (24), 11399-11415, 2019 | 17 | 2019 |
| Structure-based design and development of chemical probes targeting putative MOR-CCR5 heterodimers to inhibit opioid exacerbated HIV-1 infectivity B Huang, H Wang, Y Zheng, M Li, G Kang, V Barreto-de-Souza, ... Journal of medicinal chemistry 64 (11), 7702-7723, 2021 | 10 | 2021 |
| Design, synthesis, and biological evaluation of NAP isosteres: a switch from peripheral to central nervous system acting mu-opioid receptor antagonists PP Pagare, M Li, Y Zheng, AS Kulkarni, S Obeng, B Huang, C Ruiz, ... Journal of medicinal chemistry 65 (6), 5095-5112, 2022 | 9 | 2022 |
| Bivalent ligand aiming putative mu opioid receptor and chemokine receptor CXCR4 dimers in opioid enhanced HIV-1 entry H Ma, H Wang, M Li, V Barreto-de-Souza, BA Reinecke, R Gunta, ... ACS medicinal chemistry letters 11 (11), 2318-2324, 2020 | 9 | 2020 |
| Verifying the role of 3-hydroxy of 17-cyclopropylmethyl-4, 5α-epoxy-3, 14β-dihydroxy-6β-[(4′-pyridyl) carboxamido] morphinan derivatives via their binding affinity and … B Huang, R Gunta, H Wang, M Li, D Cao, RE Mendez, JC Gillespie, ... Bioorganic chemistry 109, 104702, 2021 | 7 | 2021 |
| Structural alterations of the “address” moiety of NAN leading to the discovery of a novel opioid receptor modulator with reduced hERG toxicity H Ma, PP Pagare, M Li, LT Neel, RE Mendez, JC Gillespie, DL Stevens, ... Journal of medicinal chemistry 66 (1), 577-595, 2022 | 6 | 2022 |
| Characterization of a Potential KOR/DOR Dual Agonist with No Apparent Abuse Liability via a Complementary Structure–Activity Relationship Study on Nalfurafine Analogues M Li, DL Stevens, M Arriaga, EA Townsend, RE Mendez, NA Blajkevch, ... ACS chemical neuroscience 13 (24), 3608-3628, 2022 | 6 | 2022 |
| Novel bivalent ligands carrying potential antinociceptive effects by targeting putative mu opioid receptor and chemokine receptor CXCR4 heterodimers H Ma, M Li, PP Pagare, H Wang, N Nassehi, EJ Santos, SS Negus, ... Bioorganic chemistry 120, 105641, 2022 | 6 | 2022 |
| Rational design, chemical syntheses, and biological evaluations of peripherally selective mu opioid receptor ligands as potential opioid induced constipation treatment B Huang, M Li, P Klongkumnuankarn, RE Mendez, JC Gillespie, ... Journal of medicinal chemistry 65 (6), 4991-5003, 2022 | 3 | 2022 |
| Agonist-promoted phosphorylation and internalization of the kappa opioid receptor in mouse brains: Lack of connection with conditioned place aversion C Chen, P Huang, K Bland, M Li, Y Zhang, LY Liu-Chen Frontiers in Pharmacology 13, 835809, 2022 | 2 | 2022 |
| Stereoselective syntheses of 3-dehydroxynaltrexamines and N-methyl-3-dehydroxynaltrexamines M Li, CMS Onge, Y Zhang Tetrahedron letters 61 (39), 152379, 2020 | 2 | 2020 |
| NCP, a dual kappa and mu opioid receptor agonist, is a potent analgesic against inflammatory pain without reinforcing or aversive properties P Huang, CK Ho, D Cao, S Inan, SM Rawls, M Li, B Huang, PP Pagare, ... Journal of Pharmacology and Experimental Therapeutics 389 (1), 106-117, 2024 | | 2024 |
| Molecular Pharmacology Profiling of Phenylfentanil and Its Analogues to Understand the Putative Involvement of an Adrenergic Mechanism in Fentanyl-Induced Respiratory Depression M Li, PP Pagare, H Ma, CM St. Onge, RE Mendez, JC Gillespie, ... Journal of Medicinal Chemistry 67 (1), 603-619, 2023 | | 2023 |
| Structure-activity Exploration of Positive Allosteric Modulators of the Mu-opioid Receptor M Li, J Traynor, S Zhang, M Stanczyk, X Gan, A White Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | | 2023 |
| Elucidating the binding mechanism of LPA species and analogs in an LPA4 receptor homology model H Wang, M Li, CM St Onge, B Fuss, Y Zhang Journal of Molecular Graphics and Modelling 116, 108274, 2022 | | 2022 |
| Systematic Structure-activity Relationship Studies of Nalfurafine M Li | | 2021 |
Dana SelleyProfessor of Pharmacology and Toxicology, Virginia Commonwealth University在 vcuhealth.org 的电子邮件经过验证
