Same substrate, many reactions: oxygen activation in flavoenzymes E Romero, JR Gómez Castellanos, G Gadda, MW Fraaije, A Mattevi Chemical reviews 118 (4), 1742-1769, 2018 | 373 | 2018 |
On the catalytic mechanism of choline oxidase Fan, G Gadda Journal of the American Chemical Society 127 (7), 2067-2074, 2005 | 149 | 2005 |
Oxygen activation in flavoprotein oxidases: the importance of being positive G Gadda Biochemistry 51 (13), 2662-2669, 2012 | 137 | 2012 |
Design and application of a class of sensors to monitor Ca2+ dynamics in high Ca2+ concentration cellular compartments S Tang, HC Wong, ZM Wang, Y Huang, J Zou, Y Zhuo, A Pennati, ... Proceedings of the National Academy of Sciences 108 (39), 16265-16270, 2011 | 132 | 2011 |
Role of Glu312 in Binding and Positioning of the Substrate for the Hydride Transfer Reaction in Choline Oxidase, O Quaye, GT Lountos, Fan, AM Orville, G Gadda Biochemistry 47 (1), 243-256, 2008 | 111 | 2008 |
On the catalytic role of the conserved active site residue His466 of choline oxidase M Ghanem, G Gadda Biochemistry 44 (3), 893-904, 2005 | 111 | 2005 |
Characterization of Cholesterol Oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum G Gadda, G Wels, L Pollegioni, S Zucchelli, D Ambrosius, MS Pilone, ... European journal of biochemistry 250 (2), 369-376, 1997 | 102 | 1997 |
Cloning, sequence analysis, and purification of choline oxidase from Arthrobacter globiformis: a bacterial enzyme involved in osmotic stress tolerance F Fan, M Ghanem, G Gadda Archives of biochemistry and biophysics 421 (1), 149-158, 2004 | 94 | 2004 |
Hydride transfer made easy in the reaction of alcohol oxidation catalyzed by flavin-dependent oxidases G Gadda Biochemistry 47 (52), 13745-13753, 2008 | 91 | 2008 |
Cloning, Expression, and Purification of Choline Dehydrogenase from the Moderate Halophile Halomonas elongata G Gadda, EE McAllister-Wilkins Applied and environmental microbiology 69 (4), 2126-2132, 2003 | 91 | 2003 |
The biochemistry of the metabolic poison propionate 3‐nitronate and its conjugate acid, 3‐nitropropionate K Francis, C Smitherman, SF Nishino, JC Spain, G Gadda IUBMB life 65 (9), 759-768, 2013 | 88 | 2013 |
Nitronate monooxygenase, a model for anionic flavin semiquinone intermediates in oxidative catalysis G Gadda, K Francis Archives of biochemistry and biophysics 493 (1), 53-61, 2010 | 85 | 2010 |
Crystallographic, Spectroscopic, and Computational Analysis of a Flavin C4a−Oxygen Adduct in Choline Oxidase, AM Orville, GT Lountos, S Finnegan, G Gadda, R Prabhakar Biochemistry 48 (4), 720-728, 2009 | 72 | 2009 |
Kinetic mechanism of choline oxidase from Arthrobacter globiformis G Gadda Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1646 (1-2), 112-118, 2003 | 72 | 2003 |
Spectroscopic and Kinetic Properties of Recombinant Choline Oxidase from Arthrobacter globiformis M Ghanem, Fan, K Francis, G Gadda Biochemistry 42 (51), 15179-15188, 2003 | 70 | 2003 |
Effects of reversing the protein positive charge in the proximity of the flavin N (1) locus of choline oxidase M Ghanem, G Gadda Biochemistry 45 (10), 3437-3447, 2006 | 69 | 2006 |
Oxygen-and temperature-dependent kinetic isotope effects in choline oxidase: correlating reversible hydride transfer with environmentally enhanced tunneling Fan, G Gadda Journal of the American Chemical Society 127 (50), 17954-17961, 2005 | 68 | 2005 |
Developing sensors for real-time measurement of high Ca2+ concentrations J Zou, AM Hofer, MM Lurtz, G Gadda, AL Ellis, N Chen, Y Huang, ... Biochemistry 46 (43), 12275-12288, 2007 | 67 | 2007 |
The COMBREX project: design, methodology, and initial results BP Anton, YC Chang, P Brown, HP Choi, LL Faller, J Guleria, Z Hu, ... PLoS biology 11 (8), e1001638, 2013 | 66 | 2013 |
Mechanistic studies of choline oxidase with betaine aldehyde and its isosteric analogue 3, 3-dimethylbutyraldehyde Fan, MW Germann, G Gadda Biochemistry 45 (6), 1979-1986, 2006 | 66 | 2006 |