Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation M Yao, BT Goult, H Chen, P Cong, MP Sheetz, J Yan Scientific reports 4 (1), 1-7, 2014 | 408 | 2014 |
The structure of an integrin/talin complex reveals the basis of inside‐out signal transduction NJ Anthis, KL Wegener, F Ye, C Kim, BT Goult, ED Lowe, I Vakonakis, ... The EMBO journal 28 (22), 3623-3632, 2009 | 400 | 2009 |
The mechanical response of talin M Yao, BT Goult, B Klapholz, X Hu, CP Toseland, Y Guo, P Cong, ... Nature communications 7 (1), 11966, 2016 | 385 | 2016 |
Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity A Kumar, M Ouyang, K Van den Dries, EJ McGhee, K Tanaka, ... Journal of Cell Biology 213 (3), 371-383, 2016 | 265 | 2016 |
The structure of the C‐terminal actin‐binding domain of talin AR Gingras, N Bate, BT Goult, L Hazelwood, I Canestrelli, JG Grossmann, ... The EMBO journal 27 (2), 458-469, 2008 | 228 | 2008 |
RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover BT Goult, T Zacharchenko, N Bate, R Tsang, F Hey, AR Gingras, PR Elliott, ... Journal of Biological Chemistry 288 (12), 8238-8249, 2013 | 225 | 2013 |
Vinculin controls talin engagement with the actomyosin machinery P Atherton, B Stutchbury, DY Wang, D Jethwa, R Tsang, ... Nature communications 6 (1), 10038, 2015 | 223 | 2015 |
Talin as a mechanosensitive signaling hub BT Goult, J Yan, MA Schwartz Journal of Cell Biology 217 (11), 3776-3784, 2018 | 217 | 2018 |
Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery J Oberoi, L Fairall, PJ Watson, JC Yang, Z Czimmerer, T Kampmann, ... Nature structural & molecular biology 18 (2), 177-184, 2011 | 191 | 2011 |
Structure of a double ubiquitin‐like domain in the talin head: a role in integrin activation BT Goult, M Bouaouina, PR Elliott, N Bate, B Patel, AR Gingras, ... The EMBO journal 29 (6), 1069-1080, 2010 | 180 | 2010 |
Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions BP Bouchet, RE Gough, YC Ammon, D van de Willige, H Post, ... Elife 5, e18124, 2016 | 179 | 2016 |
The Structure of the talin head reveals a novel extended conformation of the FERM domain PR Elliott, BT Goult, PM Kopp, N Bate, JG Grossmann, GCK Roberts, ... Structure 18 (10), 1289-1299, 2010 | 179 | 2010 |
Structural model and functional significance of pH-dependent talin–actin binding for focal adhesion remodeling J Srivastava, G Barreiro, S Groscurth, AR Gingras, BT Goult, DR Critchley, ... Proceedings of the National Academy of Sciences 105 (38), 14436-14441, 2008 | 158 | 2008 |
The Structure of an Interdomain Complex That Regulates Talin Activity*♦ BT Goult, N Bate, NJ Anthis, KL Wegener, AR Gingras, B Patel, ... Journal of biological chemistry 284 (22), 15097-15106, 2009 | 139 | 2009 |
Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: implications for talin activation BT Goult, XP Xu, AR Gingras, M Swift, B Patel, N Bate, PM Kopp, ... Journal of structural biology 184 (1), 21-32, 2013 | 135 | 2013 |
Talin dependent mechanosensitivity of cell focal adhesions J Yan, M Yao, BT Goult, MP Sheetz Cellular and molecular bioengineering 8, 151-159, 2015 | 105 | 2015 |
Structural determinants of integrin binding to the talin rod AR Gingras, WH Ziegler, AA Bobkov, MG Joyce, D Fasci, M Himmel, ... Journal of biological chemistry 284 (13), 8866-8876, 2009 | 105 | 2009 |
The structure of the N-terminus of kindlin-1: a domain important for αIIbβ3 integrin activation BT Goult, M Bouaouina, DS Harburger, N Bate, B Patel, NJ Anthis, ... Journal of molecular biology 394 (5), 944-956, 2009 | 104 | 2009 |
The tale of two talins–two isoforms to fine‐tune integrin signalling RE Gough, BT Goult FEBS letters 592 (12), 2108-2125, 2018 | 102 | 2018 |
The IDOL–UBE2D complex mediates sterol-dependent degradation of the LDL receptor L Zhang, L Fairall, BT Goult, AC Calkin, C Hong, CJ Millard, P Tontonoz, ... Genes & development 25 (12), 1262-1274, 2011 | 96 | 2011 |