Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration D Zwilling, SY Huang, KV Sathyasaikumar, FM Notarangelo, P Guidetti, ... Cell 145 (6), 863-874, 2011 | 525 | 2011 |
The kynurenine pathway modulates neurodegeneration in a Drosophila model of Huntington's disease S Campesan, EW Green, C Breda, KV Sathyasaikumar, PJ Muchowski, ... Current Biology 21 (11), 961-966, 2011 | 277 | 2011 |
Impaired kynurenine pathway metabolism in the prefrontal cortex of individuals with schizophrenia KV Sathyasaikumar, EK Stachowski, I Wonodi, RC Roberts, ... Schizophrenia bulletin 37 (6), 1147-1156, 2011 | 257 | 2011 |
Downregulated kynurenine 3-monooxygenase gene expression and enzyme activity in schizophrenia and genetic association with schizophrenia endophenotypes I Wonodi, OC Stine, KV Sathyasaikumar, RC Roberts, BD Mitchell, ... Archives of general psychiatry 68 (7), 665-674, 2011 | 179 | 2011 |
Of mice, rats and men: revisiting the quinolinic acid hypothesis of Huntington's disease R Schwarcz, P Guidetti, KV Sathyasaikumar, PJ Muchowski Progress in neurobiology 90 (2), 230-245, 2010 | 175 | 2010 |
Tryptophan-2, 3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolites C Breda, KV Sathyasaikumar, S Sograte Idrissi, FM Notarangelo, ... Proceedings of the National Academy of Sciences 113 (19), 5435-5440, 2016 | 148 | 2016 |
Targeted deletion of kynurenine 3-monooxygenase in mice: a new tool for studying kynurenine pathway metabolism in periphery and brain F Giorgini, SY Huang, KV Sathyasaikumar, FM Notarangelo, ... Journal of Biological Chemistry 288 (51), 36554-36566, 2013 | 126 | 2013 |
Fulminant hepatic failure in rats induces oxidative stress differentially in cerebral cortex, cerebellum and pons medulla KV Sathyasaikumar, I Swapna, PVB Reddy, CRK Murthy, A Dutta Gupta, ... Neurochemical research 32, 517-524, 2007 | 92 | 2007 |
Co-administration of C-Phycocyanin ameliorates thioacetamide-induced hepatic encephalopathy in Wistar rats KV Sathyasaikumar, I Swapna, PVB Reddy, CRK Murthy, KR Roy, ... Journal of the neurological sciences 252 (1), 67-75, 2007 | 83 | 2007 |
Tryptophan 2, 3-dioxygenase and indoleamine 2, 3-dioxygenase 1 make separate, tissue-specific contributions to basal and inflammation-induced kynurenine pathway metabolism in mice PB Larkin, KV Sathyasaikumar, FM Notarangelo, H Funakoshi, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (11), 2345-2354, 2016 | 80 | 2016 |
Dysfunctional kynurenine pathway metabolism in the R6/2 mouse model of Huntington’s disease KV Sathyasaikumar, EK Stachowski, L Amori, P Guidetti, PJ Muchowski, ... Journal of neurochemistry 113 (6), 1416-1425, 2010 | 73 | 2010 |
Crystal structure-based selective targeting of the pyridoxal 5′-phosphate dependent enzyme kynurenine aminotransferase II for cognitive enhancement F Rossi, C Valentina, S Garavaglia, KV Sathyasaikumar, R Schwarcz, ... Journal of medicinal chemistry 53 (15), 5684-5689, 2010 | 50 | 2010 |
Xanthurenic acid formation from 3-hydroxykynurenine in the mammalian brain: neurochemical characterization and physiological effects KV Sathyasaikumar, M Tararina, HQ Wu, SA Neale, F Weisz, TE Salt, ... Neuroscience 367, 85-97, 2017 | 45 | 2017 |
Drosophila eye color mutants as therapeutic tools for Huntington disease EW Green, S Campesan, C Breda, KV Sathyasaikumar, PJ Muchowski, ... Fly 6 (2), 117-120, 2012 | 40 | 2012 |
Changes in cerebral membrane lipid composition and fluidity during thioacetamide‐induced hepatic encephalopathy I Swapna, KV Sathyasaikumar, CRK Murthy, A Dutta‐Gupta, ... Journal of neurochemistry 98 (6), 1899-1907, 2006 | 29 | 2006 |
Application of frog (Rana tigerina Daudin) skin collagen as a novel substrate in cell culture. KV Kumar, KP Sai, M Babu J Biomed Mater Res. 61 (2), 197-202, 2002 | 26 | 2002 |
Enzymatic transamination of d‐kynurenine generates kynurenic acid in rat and human brain V Pérez‐de la Cruz, L Amori, KV Sathyasaikumar, XD Wang, ... Journal of neurochemistry 120 (6), 1026-1035, 2012 | 22 | 2012 |
N-acetylcysteine inhibits kynurenine aminotransferase II T Blanco-Ayala, KV Sathyasaikumar, JD Uys, V Perez-De-La-Cruz, ... Neuroscience 444, 160-169, 2020 | 20 | 2020 |
Alterations in kinetic and thermotropic properties of cerebral membrane-bound acetylcholineesterase during thioacetamide-induced hepatic encephalopathy: correlation with … I Swapna, KV SathyaSaikumar, CRK Murthy, AD Gupta, B Senthilkumaran Brain research 1153, 188-195, 2007 | 20 | 2007 |
Co-administration of C-phycocyanin ameliorates KV Sathyasaikumar, I Swapna, PVB Reddy, CRK Murthy, KR Roy, ... | 20 | 2007 |