BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function SB Cantor, DW Bell, S Ganesan, EM Kass, R Drapkin, S Grossman, ... Cell 105 (1), 149-160, 2001 | 865 | 2001 |
Replication fork stability confers chemoresistance in BRCA-deficient cells A Ray Chaudhuri, E Callen, X Ding, E Gogola, AA Duarte, JE Lee, ... Nature 535 (7612), 382-387, 2016 | 831 | 2016 |
Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells J Chen, DP Silver, D Walpita, SB Cantor, AF Gazdar, G Tomlinson, ... Molecular cell 2 (3), 317-328, 1998 | 798 | 1998 |
RTEL1 maintains genomic stability by suppressing homologous recombination LJ Barber, JL Youds, JD Ward, MJ McIlwraith, NJ O'Neil, MIR Petalcorin, ... Cell 135 (2), 261-271, 2008 | 462 | 2008 |
BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ R Litman, M Peng, Z Jin, F Zhang, J Zhang, S Powell, PR Andreassen, ... Cancer cell 8 (3), 255-265, 2005 | 455 | 2005 |
BRCA1, BRCA2, and Rad51 operate in a common DNA damage response pathway JJ Chen, D Silver, S Cantor, DM Livingston, R Scully Cancer research 59 (7_Supplement), 1752s-1756s, 1999 | 394 | 1999 |
Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes RA Greenberg, B Sobhian, S Pathania, SB Cantor, Y Nakatani, ... Genes & development 20 (1), 34-46, 2006 | 392 | 2006 |
Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases SB Cantor, T Urano, LA Feig Molecular and cellular biology 15 (8), 4578-4584, 1995 | 375 | 1995 |
Evidence for a Ras/Ral signaling cascade LA Feig, T Urano, S Cantor Trends in biochemical sciences 21 (11), 438-441, 1996 | 305 | 1996 |
The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations S Cantor, R Drapkin, F Zhang, Y Lin, J Han, S Pamidi, DM Livingston Proceedings of the National Academy of Sciences 101 (8), 2357-2362, 2004 | 298 | 2004 |
Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure WS Joo, PD Jeffrey, SB Cantor, MS Finnin, DM Livingston, NP Pavletich Genes & development 16 (5), 583-593, 2002 | 280 | 2002 |
Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency K Cong, M Peng, AN Kousholt, WTC Lee, S Lee, S Nayak, J Krais, ... Molecular cell 81 (15), 3128-3144. e7, 2021 | 248 | 2021 |
The FANCJ/MutLα interaction is required for correction of the cross‐link response in FA‐J cells M Peng, R Litman, J Xie, S Sharma, RM Brosh Jr, SB Cantor The EMBO journal 26 (13), 3238-3249, 2007 | 206 | 2007 |
Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4 S Guillemette, RW Serra, M Peng, JA Hayes, PA Konstantinopoulos, ... Genes & development 29 (5), 489-494, 2015 | 171 | 2015 |
Replication gaps underlie BRCA deficiency and therapy response NJ Panzarino, JJ Krais, K Cong, M Peng, M Mosqueda, SU Nayak, ... Cancer research 81 (5), 1388-1397, 2021 | 151 | 2021 |
Analysis of the DNA Substrate Specificity of the Human BACH1 HelicaseAssociated with BreastCancer R Gupta, S Sharma, JA Sommers, Z Jin, SB Cantor, RM Brosh Journal of Biological Chemistry 280 (27), 25450-25460, 2005 | 149 | 2005 |
Hereditary breast cancer and the BRCA1-associated FANCJ/BACH1/BRIP1 SB Cantor, S Guillemette Future oncology 7 (2), 253-261, 2011 | 134 | 2011 |
FANCJ uses its motor ATPase to destabilize protein-DNA complexes, unwind triplexes, and inhibit RAD51 strand exchange JA Sommers, N Rawtani, R Gupta, DV Bugreev, AV Mazin, SB Cantor, ... Journal of Biological Chemistry 284 (12), 7505-7517, 2009 | 127 | 2009 |
FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein R Gupta, S Sharma, JA Sommers, MK Kenny, SB Cantor, RM Brosh Jr Blood, The Journal of the American Society of Hematology 110 (7), 2390-2398, 2007 | 125 | 2007 |
BACH1 is a DNA repair protein supporting BRCA1 damage response M Peng, R Litman, Z Jin, G Fong, SB Cantor Oncogene 25 (15), 2245-2253, 2006 | 116 | 2006 |