| A three-dimensional human neural cell culture model of Alzheimer’s disease SH Choi, YH Kim, M Hebisch, C Sliwinski, S Lee, C D’Avanzo, H Chen, ... Nature 515 (7526), 274-278, 2014 | 1279 | 2014 |
| Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model SH Choi, E Bylykbashi, ZK Chatila, SW Lee, B Pulli, GD Clemenson, ... Science 361 (6406), eaan8821, 2018 | 695 | 2018 |
| A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer’s disease J Park, I Wetzel, I Marriott, D Dréau, C D’Avanzo, DY Kim, RE Tanzi, ... Nature neuroscience 21 (7), 941-951, 2018 | 580 | 2018 |
| BACE1 regulates voltage-gated sodium channels and neuronal activity DY Kim, BW Carey, H Wang, LAM Ingano, AM Binshtok, MH Wertz, ... Nature cell biology 9 (7), 755-764, 2007 | 386 | 2007 |
| Cellular and molecular pathways of ischemic neuronal death SJ Won, DY Kim, BJ Gwag BMB reports 35 (1), 67-86, 2002 | 376 | 2002 |
| The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease B Hutter-Paier, HJ Huttunen, L Puglielli, CB Eckman, DY Kim, ... Neuron 44 (2), 227-238, 2004 | 333 | 2004 |
| A 3D human neural cell culture system for modeling Alzheimer's disease YH Kim, SH Choi, C D'avanzo, M Hebisch, C Sliwinski, E Bylykbashi, ... Nature protocols 10 (7), 985-1006, 2015 | 265 | 2015 |
| ADAM10 missense mutations potentiate β-amyloid accumulation by impairing prodomain chaperone function J Suh, SH Choi, DM Romano, MA Gannon, AN Lesinski, DY Kim, ... Neuron 80 (2), 385-401, 2013 | 241 | 2013 |
| Nectin-1α, an immunoglobulin-like receptor involved in the formation of synapses, is a substrate for presenilin/γ-secretase-like cleavage DY Kim, LAMK Ingano, DM Kovacs Journal of Biological Chemistry 277 (51), 49976-49981, 2002 | 223 | 2002 |
| Blood–brain barrier dysfunction in a 3D in vitro model of Alzheimer's disease Y Shin, SH Choi, E Kim, E Bylykbashi, JA Kim, S Chung, DY Kim, ... Advanced science 6 (20), 1900962, 2019 | 219 | 2019 |
| Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H2O2− production H Chun, H Im, YJ Kang, Y Kim, JH Shin, W Won, J Lim, Y Ju, YM Park, ... Nature neuroscience 23 (12), 1555-1566, 2020 | 202 | 2020 |
| Presenilin/γ-secretase-mediated cleavage of the voltage-gated sodium channel β2-subunit regulates cell adhesion and migration DY Kim, LAMK Ingano, BW Carey, WH Pettingell, DM Kovacs Journal of Biological Chemistry 280 (24), 23251-23261, 2005 | 189 | 2005 |
| 3D culture models of Alzheimer’s disease: a road map to a “cure-in-a-dish” SH Choi, YH Kim, L Quinti, RE Tanzi, DY Kim Molecular neurodegeneration 11, 1-11, 2016 | 141 | 2016 |
| Gating connexin 43 channels reconstituted in lipid vesicles by mitogen-activated protein kinase phosphorylation DY Kim, Y Kam, SK Koo, CO Joe Journal of Biological Chemistry 274 (9), 5581-5587, 1999 | 128 | 1999 |
| Amyloid-β42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer’s disease SS Kwak, KJ Washicosky, E Brand, D von Maydell, J Aronson, S Kim, ... Nature communications 11 (1), 1377, 2020 | 121 | 2020 |
| Human neurospheroid arrays for in vitro studies of Alzheimer’s disease M Jorfi, C D’Avanzo, RE Tanzi, DY Kim, D Irimia Scientific Reports 8 (1), 1-13, 2018 | 115 | 2018 |
| Cleavage of 14-3-3 protein by caspase-3 facilitates bad interaction with Bcl-x (L) during apoptosis J Won, DY Kim, M La, D Kim, GG Meadows, CO Joe Journal of Biological Chemistry 278 (21), 19347-19351, 2003 | 115 | 2003 |
| Alzheimer's in 3D culture: challenges and perspectives C D'avanzo, J Aronson, YH Kim, SH Choi, RE Tanzi, DY Kim Bioessays 37 (10), 1139-1148, 2015 | 111 | 2015 |
| Three‐dimensional models of the human brain development and diseases M Jorfi, C D'Avanzo, DY Kim, D Irimia Advanced healthcare materials 7 (1), 1700723, 2018 | 107 | 2018 |
| Reduced sodium channel Nav1. 1 levels in BACE1-null mice DY Kim, MT Gersbacher, P Inquimbert, DM Kovacs Journal of Biological Chemistry 286 (10), 8106-8116, 2011 | 107 | 2011 |
Rudolph E TanziHarvard在 helix.mgh.harvard.edu 的电子邮件经过验证
