Increased dosage of mammalian Sir2 in pancreatic β cells enhances glucose-stimulated insulin secretion in mice KA Moynihan, AA Grimm, MM Plueger, E Bernal-Mizrachi, E Ford, ... Cell metabolism 2 (2), 105-117, 2005 | 809 | 2005 |
Natural history of β-cell adaptation and failure in type 2 diabetes EU Alejandro, B Gregg, M Blandino-Rosano, C Cras-Méneur, ... Molecular aspects of medicine 42, 19-41, 2015 | 278 | 2015 |
Inhibition of Foxo1 protects pancreatic islet β-cells against fatty acid and endoplasmic reticulum stress–induced apoptosis SC Martinez, K Tanabe, C Cras-Méneur, NA Abumrad, E Bernal-Mizrachi, ... Diabetes 57 (4), 846-859, 2008 | 278 | 2008 |
Akt induces β-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity S Fatrai, L Elghazi, N Balcazar, C Cras-Méneur, I Krits, H Kiyokawa, ... Diabetes 55 (2), 318-325, 2006 | 256 | 2006 |
Epidermal growth factor increases undifferentiated pancreatic embryonic cells in vitro: a balance between proliferation and differentiation C Cras-Méneur, L Elghazi, P Czernichow, R Scharfmann Diabetes 50 (7), 1571-1579, 2001 | 186 | 2001 |
Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation L Elghazi, C Cras-Méneur, P Czernichow, R Scharfmann Proceedings of the National Academy of Sciences 99 (6), 3884-3889, 2002 | 154 | 2002 |
Glucose regulates Foxo1 through insulin receptor signaling in the pancreatic islet β-cell SC Martinez, C Cras-Méneur, E Bernal-Mizrachi, MA Permutt Diabetes 55 (6), 1581-1591, 2006 | 150 | 2006 |
Genetic deficiency of glycogen synthase kinase-3β corrects diabetes in mouse models of insulin resistance K Tanabe, Z Liu, S Patel, BW Doble, L Li, C Cras-Méneur, SC Martinez, ... PLoS biology 6 (2), e37, 2008 | 130 | 2008 |
Reduced expression of the insulin receptor in mouse insulinoma (MIN6) cells reveals multiple roles of insulin signaling in gene expression, proliferation, insulin content, and … M Ohsugi, C Cras-Méneur, Y Zhou, E Bernal-Mizrachi, JD Johnson, ... Journal of Biological Chemistry 280 (6), 4992-5003, 2005 | 123 | 2005 |
Conditional ablation of Gsk-3β in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice Y Liu, K Tanabe, D Baronnier, S Patel, J Woodgett, C Cras-Méneur, ... Diabetologia 53, 2600-2610, 2010 | 119 | 2010 |
Regulation of β‐cell mass and function by the Akt/protein kinase B signalling pathway L Elghazi, L Rachdi, AJ Weiss, C Cras‐Méneur, E Bernal‐Mizrachi Diabetes, Obesity and Metabolism 9, 147-157, 2007 | 117 | 2007 |
mTORC1 signaling and regulation of pancreatic β-cell mass M Blandino-Rosano, AY Chen, JO Scheys, EU Alejandro, AP Gould, ... Cell Cycle 11 (10), 1892-1902, 2012 | 101 | 2012 |
Decreased IRS signaling impairs β-cell cycle progression and survival in transgenic mice overexpressing S6K in β-cells L Elghazi, N Balcazar, M Blandino-Rosano, C Cras-Méneur, S Fatrai, ... Diabetes 59 (10), 2390-2399, 2010 | 76 | 2010 |
Presenilins, Notch dose control the fate of pancreatic endocrine progenitors during a narrow developmental window C Cras-Méneur, L Li, R Kopan, MA Permutt Genes & development 23 (17), 2088-2101, 2009 | 72 | 2009 |
Transcriptional program of the endocrine pancreas in mice and humans KH Kaestner, CS Lee, LM Scearce, JE Brestelli, A Arsenlis, PP Le, ... Diabetes 52 (7), 1604-1610, 2003 | 68 | 2003 |
Glucose and insulin treatment of insulinoma cells results in transcriptional regulation of a common set of genes M Ohsugi, C Cras-Méneur, Y Zhou, W Warren, E Bernal-Mizrachi, ... Diabetes 53 (6), 1496-1508, 2004 | 65 | 2004 |
Ventromedial hypothalamic nucleus neuronal subset regulates blood glucose independently of insulin JN Flak, PB Goforth, J Dell’Orco, PV Sabatini, C Li, N Bozadjieva, ... The Journal of clinical investigation 130 (6), 2943-2952, 2020 | 60 | 2020 |
Role of nutrients and mTOR signaling in the regulation of pancreatic progenitors development L Elghazi, M Blandino-Rosano, E Alejandro, C Cras-Méneur, ... Molecular metabolism 6 (6), 560-573, 2017 | 56 | 2017 |
Importance of β-catenin in glucose and energy homeostasis L Elghazi, AP Gould, AJ Weiss, DJ Barker, J Callaghan, D Opland, ... Scientific reports 2 (1), 693, 2012 | 56 | 2012 |
An expression profile of human pancreatic islet mRNAs by Serial Analysis of Gene Expression (SAGE) C Cras-Meneur, H Inoue, Y Zhou, M Ohsugi, E Bernal-Mizrachi, D Pape, ... Diabetologia 47, 284-299, 2004 | 55 | 2004 |