TDP-43 triggers mitochondrial DNA release via mPTP to activate cGAS/STING in ALS CH Yu, S Davidson, CR Harapas, JB Hilton, MJ Mlodzianoski, ... Cell 183 (3), 636-649. e18, 2020 | 581 | 2020 |
Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson’s disease H Hall, S Reyes, N Landeck, C Bye, G Leanza, K Double, L Thompson, ... Brain 137 (9), 2493-2508, 2014 | 304 | 2014 |
HIV-1 infection of human macrophages directly induces viperin which inhibits viral production N Nasr, S Maddocks, SG Turville, AN Harman, N Woolger, KJ Helbig, ... Blood 120 (4), 778-788, 2012 | 261 | 2012 |
Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis AK Walker, MA Farg, CR Bye, CA McLean, MK Horne, JD Atkin Brain 133 (1), 105-116, 2010 | 183 | 2010 |
Association of regulatory T-cell expansion with progression of amyotrophic lateral sclerosis: a study of humans and a transgenic mouse model RK Sheean, FC McKay, E Cretney, CR Bye, ND Perera, D Tomas, ... JAMA neurology 75 (6), 681-689, 2018 | 149 | 2018 |
Gene expression and genotyping studies implicate the interleukin 7 receptor in the pathogenesis of primary progressive multiple sclerosis DR Booth, AT Arthur, SM Teutsch, C Bye, J Rubio, PJ Armati, JD Pollard, ... Journal of molecular medicine 83, 822-830, 2005 | 123 | 2005 |
Identification of lineage relationships and novel markers of blood and skin human dendritic cells AN Harman, CR Bye, N Nasr, KJ Sandgren, M Kim, SK Mercier, ... The Journal of Immunology 190 (1), 66-79, 2013 | 119 | 2013 |
Wnt5a regulates midbrain dopaminergic axon growth and guidance BD Blakely, CR Bye, CV Fernando, MK Horne, ML Macheda, SA Stacker, ... PloS one 6 (3), e18373, 2011 | 117 | 2011 |
HIV induces maturation of monocyte-derived dendritic cells and Langerhans cells AN Harman, J Wilkinson, CR Bye, L Bosnjak, JL Stern, M Nicholle, J Lai, ... The Journal of Immunology 177 (10), 7103-7113, 2006 | 110 | 2006 |
Birth dating of midbrain dopamine neurons identifies A9 enriched tissue for transplantation into parkinsonian mice CR Bye, LH Thompson, CL Parish Experimental neurology 236 (1), 58-68, 2012 | 95 | 2012 |
Determination of suitable housekeeping genes for normalisation of quantitative real time PCR analysis of cells infected with human immunodeficiency virus and herpes viruses S Watson, S Mercier, C Bye, J Wilkinson, AL Cunningham, AN Harman Virology journal 4, 1-5, 2007 | 89 | 2007 |
Viral delivery of GDNF promotes functional integration of human stem cell grafts in Parkinson’s disease CW Gantner, IR de Luzy, JA Kauhausen, N Moriarty, JC Niclis, CR Bye, ... Cell Stem Cell 26 (4), 511-526. e5, 2020 | 78 | 2020 |
Genes implicated in multiple sclerosis pathogenesis from consilience of genotyping and expression profiles in relapse and remission AT Arthur, PJ Armati, C Bye, ... BMC medical genetics 9, 1-12, 2008 | 76 | 2008 |
Modulation of feeding by chronic rAAV expression of a relaxin-3 peptide agonist in rat hypothalamus DE Ganella, GE Callander, S Ma, CR Bye, AL Gundlach, RAD Bathgate Gene therapy 20 (7), 703-716, 2013 | 72 | 2013 |
HIV-1–infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase AN Harman, M Kraus, CR Bye, K Byth, SG Turville, O Tang, SK Mercier, ... Blood 114 (1), 85-94, 2009 | 69 | 2009 |
Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors CR Bye, ME Jönsson, A Björklund, CL Parish, LH Thompson Proceedings of the National Academy of Sciences 112 (15), E1946-E1955, 2015 | 66 | 2015 |
Glycogen synthase kinase 3β and activin/nodal inhibition in human embryonic stem cells induces a pre-neuroepithelial state that is required for specification to a floor plate … M Denham, C Bye, J Leung, BJ Conley, LH Thompson, M Dottori Stem cells 30 (11), 2400-2411, 2012 | 63 | 2012 |
Neuronal activity regulates expression of tyrosine hydroxylase in adult mouse substantia nigra pars compacta neurons TD Aumann, K Egan, J Lim, WC Boon, CR Bye, HK Chua, N Baban, ... Journal of neurochemistry 116 (4), 646-658, 2011 | 61 | 2011 |
Efficiently specified ventral midbrain dopamine neurons from human pluripotent stem cells under xeno-free conditions restore motor deficits in parkinsonian rodents JC Niclis, CW Gantner, WF Alsanie, SJ McDougall, CR Bye, AG Elefanty, ... Stem cells translational medicine 6 (3), 937-948, 2017 | 59 | 2017 |
Dopamine D2 receptor knockout mice develop features of Parkinson disease RB Tinsley, CR Bye, CL Parish, A Tziotis‐Vais, S George, JG Culvenor, ... Annals of neurology 66 (4), 472-484, 2009 | 54 | 2009 |