| Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir W Yin, C Mao, X Luan, DD Shen, Q Shen, H Su, X Wang, F Zhou, W Zhao, ... Science 368 (6498), 1499-1504, 2020 | 1214 | 2020 |
| Structure of the µ-opioid receptor–Gi protein complex A Koehl, H Hu, S Maeda, Y Zhang, Q Qu, JM Paggi, NR Latorraca, ... Nature 558 (7711), 547-552, 2018 | 632 | 2018 |
| Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein Y Zhang, B Sun, D Feng, H Hu, M Chu, Q Qu, JT Tarrasch, S Li, ... Nature 546 (7657), 248-253, 2017 | 548 | 2017 |
| Phase-plate cryo-EM structure of a class B GPCR–G-protein complex YL Liang, M Khoshouei, M Radjainia, Y Zhang, A Glukhova, J Tarrasch, ... Nature 546 (7656), 118-123, 2017 | 490 | 2017 |
| Structural insights into the activation of metabotropic glutamate receptors A Koehl, H Hu, D Feng, B Sun, Y Zhang, MJ Robertson, M Chu, ... Nature 566 (7742), 79-84, 2019 | 277 | 2019 |
| Conformational transitions of a neurotensin receptor 1–Gi1 complex HE Kato, Y Zhang, H Hu, CM Suomivuori, FMN Kadji, J Aoki, KK Kumar, ... Nature 572 (7767), 80-85, 2019 | 222 | 2019 |
| Structure and dynamics of the active human parathyroid hormone receptor-1 LH Zhao, S Ma, I Sutkeviciute, DD Shen, XE Zhou, PW de Waal, CY Li, ... Science 364 (6436), 148-153, 2019 | 201 | 2019 |
| A complex structure of arrestin-2 bound to a G protein-coupled receptor W Yin, Z Li, M Jin, YL Yin, PW De Waal, K Pal, Y Yin, X Gao, Y He, J Gao, ... Cell research 29 (12), 971-983, 2019 | 190 | 2019 |
| Structural insights into the lipid and ligand regulation of serotonin receptors P Xu, S Huang, H Zhang, C Mao, XE Zhou, X Cheng, IA Simon, DD Shen, ... Nature 592 (7854), 469-473, 2021 | 182 | 2021 |
| Structural insights into the human D1 and D2 dopamine receptor signaling complexes Y Zhuang, P Xu, C Mao, L Wang, B Krumm, XE Zhou, S Huang, H Liu, ... Cell 184 (4), 931-942. e18, 2021 | 178 | 2021 |
| Highly efficient production of soluble proteins from insoluble inclusion bodies by a two-step-denaturing and refolding method Z Yang, L Zhang, Y Zhang, T Zhang, Y Feng, X Lu, W Lan, J Wang, H Wu, ... PloS one 6 (7), e22981, 2011 | 161 | 2011 |
| Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy J Duan, D Shen, XE Zhou, P Bi, Q Liu, Y Tan, Y Zhuang, H Zhang, P Xu, ... Nature communications 11 (1), 4121, 2020 | 141 | 2020 |
| Structures of the glucocorticoid-bound adhesion receptor GPR97–Go complex YQ Ping, C Mao, P Xiao, RJ Zhao, Y Jiang, Z Yang, WT An, DD Shen, ... Nature 589 (7843), 620-626, 2021 | 118 | 2021 |
| Structural basis of GPBAR activation and bile acid recognition F Yang, C Mao, L Guo, J Lin, Q Ming, P Xiao, X Wu, Q Shen, S Guo, ... Nature 587 (7834), 499-504, 2020 | 115 | 2020 |
| Structure and conformational dynamics of a COMPASS histone H3K4 methyltransferase complex Q Qu, Y Takahashi, Y Yang, H Hu, Y Zhang, JS Brunzelle, JF Couture, ... Cell 174 (5), 1117-1126. e12, 2018 | 101 | 2018 |
| Toward a structural understanding of class B GPCR peptide binding and activation YL Liang, MJ Belousoff, P Zhao, C Koole, MM Fletcher, TT Truong, ... Molecular cell 77 (3), 656-668. e5, 2020 | 96 | 2020 |
| Cryo-EM structures of inactive and active GABA B receptor C Mao, C Shen, C Li, DD Shen, C Xu, S Zhang, R Zhou, Q Shen, LN Chen, ... Cell Research, 564-573, 2020 | 85 | 2020 |
| The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B Y Zhang, H Yang, X Guo, N Rong, Y Song, Y Xu, W Lan, X Zhang, M Liu, ... Protein & cell 5 (11), 837-850, 2014 | 83 | 2014 |
| Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors F Zhao, Q Zhou, Z Cong, K Hang, X Zou, C Zhang, Y Chen, A Dai, A Liang, ... Nature Communications 13 (1), 1057, 2022 | 81 | 2022 |
| Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin M Shalev-Benami, Y Zhang, H Rozenberg, Y Nobe, M Taoka, D Matzov, ... Nature communications 8 (1), 1589, 2017 | 81 | 2017 |
