| Helper virus-free transfer of herpes simplex virus type 1 plasmid vectors into neural cells C Fraefel, S Song, F Lim, P Lang, L Yu, Y Wang, P Wild, AI Geller Journal of virology 70 (10), 7190-7197, 1996 | 340 | 1996 |
| Downregulated microRNA-200a in meningiomas promotes tumor growth by reducing E-cadherin and activating the Wnt/β-catenin signaling pathway O Saydam, Y Shen, T Würdinger, O Senol, E Boke, MF James, ... Molecular and cellular biology 29 (21), 5923-5940, 2009 | 334 | 2009 |
| Herpes Simplex Virus Type 1 DNA Amplified as Bacterial Artificial Chromosome in Escherichia coli: Rescue of Replication-Competent Virus Progeny and … Y Saeki, T Ichikawa, A Saeki, EA Chiocca, K Tobler, M Ackermann, ... Human gene therapy 9 (18), 2787-2794, 1998 | 292 | 1998 |
| Improved helper virus-free packaging system for HSV amplicon vectors using an ICP27-deleted, oversized HSV-1 DNA in a bacterial artificial chromosome Y Saeki, C Fraefel, T Ichikawa, XO Breakefield, EA Chiocca Molecular Therapy 3 (4), 591-601, 2001 | 242 | 2001 |
| Functional roles of the tegument proteins of herpes simplex virus type 1 BJ Kelly, C Fraefel, AL Cunningham, RJ Diefenbach Virus research 145 (2), 173-186, 2009 | 231 | 2009 |
| HSV/AAV hybrid amplicon vectors extend transgene expression in human glioma cells KM Johnston, D Jacoby, PA Pechan, C Fraefel, P Borghesani, ... Human gene therapy 8 (3), 359-370, 1997 | 190 | 1997 |
| Immediate-early RNA 2.9 and early RNA 2.6 of bovine herpesvirus 1 are 3'coterminal and encode a putative zinc finger transactivator protein UV Wirth, C Fraefel, B Vogt, C Vlcek, V Paces, M Schwyzer Journal of Virology 66 (5), 2763-2772, 1992 | 184 | 1992 |
| Herpes simplex virus 1 envelopment follows two diverse pathways H Leuzinger, U Ziegler, EM Schraner, C Fraefel, DL Glauser, I Heid, ... Journal of virology 79 (20), 13047-13059, 2005 | 166 | 2005 |
| The interplay between adeno-associated virus and its helper viruses AF Meier, C Fraefel, M Seyffert Viruses 12 (6), 662, 2020 | 130 | 2020 |
| Quantification of feline herpesvirus 1 DNA in ocular fluid samples of clinically diseased cats by real-time TaqMan PCR A Vogtlin, C Fraefel, S Albini, CM Leutenegger, E Schraner, B Spiess, ... Journal of Clinical Microbiology 40 (2), 519-523, 2002 | 127 | 2002 |
| Gene transfer to the nigrostriatal system by hybrid herpes simplex virus/adeno-associated virus amplicon vectors LC Costantini, Jacoby, S Wang, C Fraefel, XO Breakefield, O Isacson Human gene therapy 10 (15), 2481-2494, 1999 | 125 | 1999 |
| Gene transfer into hepatocytes mediated by helper virus-free HSV/AAV hybrid vectors C Fraefel, DR Jacoby, C Lage, H Hilderbrand, JY Chou, FW Alt, ... Molecular Medicine 3, 813-825, 1997 | 123 | 1997 |
| MxB is an interferon-induced restriction factor of human herpesviruses M Crameri, M Bauer, N Caduff, R Walker, F Steiner, FD Franzoso, C Gujer, ... Nature communications 9 (1), 1980, 2018 | 120 | 2018 |
| HSV-1 amplicon vectors—simplicity and versatility M Sena-Esteves, Y Saeki, C Fraefel, XO Breakefield Molecular Therapy 2 (1), 9-15, 2000 | 116 | 2000 |
| Identification and zinc dependence of the bovine herpesvirus 1 transactivator protein BICP0 C Fraefel, J Zeng, Y Choffat, M Engels, M Schwyzer, M Ackermann Journal of virology 68 (5), 3154-3162, 1994 | 112 | 1994 |
| Herpes simplex virus type 1/adeno-associated virus hybrid vectors mediate site-specific integration at the adeno-associated virus preintegration site, AAVS1, on human chromosome 19 T Heister, I Heid, M Ackermann, C Fraefel Journal of virology 76 (14), 7163-7173, 2002 | 106 | 2002 |
| Herpes simplex virus 1 amplicon vector-mediated siRNA targeting epidermal growth factor receptor inhibits growth of human glioma cells in vivo O Saydam, DL Glauser, I Heid, G Turkeri, M Hilbe, AH Jacobs, ... Molecular Therapy 12 (5), 803-812, 2005 | 105 | 2005 |
| BAC-VAC, a novel generation of (DNA) vaccines: a bacterial artificial chromosome (BAC) containing a replication-competent, packaging-defective virus genome induces protective … M Suter, AM Lew, P Grob, GJ Adema, M Ackermann, K Shortman, ... Proceedings of the National Academy of Sciences 96 (22), 12697-12702, 1999 | 104 | 1999 |
| Rotavirus viroplasm fusion and perinuclear localization are dynamic processes requiring stabilized microtubules C Eichwald, F Arnoldi, AS Laimbacher, EM Schraner, C Fraefel, P Wild, ... Public Library of Science 7 (10), e47947, 2012 | 93 | 2012 |
| HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part II. Vector systems and applications A Jacobs, XO Breakefield, C Fraefel Neoplasia 1 (5), 402-416, 1999 | 93 | 1999 |
