| Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates A Savastano, A Ibáñez de Opakua, M Rankovic, M Zweckstetter Nature communications 11 (1), 6041, 2020 | 310 | 2020 |
| A novel SNCA A30G mutation causes familial Parkinsonʼs disease H Liu, C Koros, T Strohäker, C Schulte, M Bozi, S Varvaresos, ... Movement Disorders 36 (7), 1624-1633, 2021 | 86 | 2021 |
| Structure of p15PAF–PCNA complex and implications for clamp sliding during DNA replication and repair A De Biasio, AI De Opakua, GB Mortuza, R Molina, TN Cordeiro, ... Nature communications 6 (1), 6439, 2015 | 84 | 2015 |
| TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress S Hoffmann, S Smedegaard, K Nakamura, GB Mortuza, M Räschle, ... Journal of Cell Biology 212 (1), 63-75, 2016 | 75 | 2016 |
| The C-terminal RNA binding motif of HuR is a multi-functional domain leading to HuR oligomerization and binding to U-rich RNA targets RM Scheiba, AI de Opakua, A Díaz-Quintana, I Cruz-Gallardo, ... RNA biology 11 (10), 1250-1261, 2014 | 73 | 2014 |
| Molecular basis of small-molecule binding to α-synuclein P Robustelli, A Ibanez-de-Opakua, C Campbell-Bezat, F Giordanetto, ... Journal of the American Chemical Society 144 (6), 2501-2510, 2022 | 64 | 2022 |
| Nucleotide binding triggers a conformational change of the CBS module of the magnesium transporter CNNM2 from a twisted towards a flat structure MÁ Corral-Rodríguez, M Stuiver, G Abascal-Palacios, T Diercks, ... Biochemical journal 464 (1), 23-34, 2014 | 62 | 2014 |
| p15PAF is an intrinsically disordered protein with nonrandom structural preferences at sites of interaction with other proteins A De Biasio, AI De Opakua, TN Cordeiro, M Villate, N Merino, N Sibille, ... Biophysical journal 106 (4), 865-874, 2014 | 59 | 2014 |
| Co-factor-free aggregation of tau into seeding-competent RNA-sequestering amyloid fibrils P Chakraborty, G Rivière, S Liu, AI de Opakua, R Dervişoğlu, A Hebestreit, ... Nature Communications 12 (1), 4231, 2021 | 53 | 2021 |
| Condensed-phase signaling can expand kinase specificity and respond to macromolecular crowding D Sang, T Shu, CF Pantoja, AI de Opakua, M Zweckstetter, LJ Holt Molecular cell 82 (19), 3693-3711. e10, 2022 | 48 | 2022 |
| Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-binding and activating motif AI de Opakua, K Parag-Sharma, V DiGiacomo, N Merino, A Leyme, ... Nature communications 8 (1), 15163, 2017 | 45 | 2017 |
| Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution T Ukmar-Godec, P Fang, A Ibáñez de Opakua, F Henneberg, A Godec, ... Science advances 6 (30), eaba3916, 2020 | 44 | 2020 |
| Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization A Dominguez-Meijide, E Vasili, A König, MS Cima-Omori, ... Scientific reports 10 (1), 12827, 2020 | 39 | 2020 |
| A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity ST Kumar, AL Mahul-Mellier, RN Hegde, G Rivière, R Moons, ... Science advances 8 (17), eabn0044, 2022 | 35 | 2022 |
| Determination of complex small‐molecule structures using molecular alignment simulation A Ibáñez de Opakua, F Klama, IE Ndukwe, GE Martin, RT Williamson, ... Angewandte Chemie International Edition 59 (15), 6172-6176, 2020 | 31* | 2020 |
| The tumor suppressor ING5 is a dimeric, bivalent recognition molecule of the histone H3K4me3 mark G Ormaza, JA Rodríguez, AI de Opakua, N Merino, M Villate, I Gorroño, ... Journal of molecular biology 431 (12), 2298-2319, 2019 | 25 | 2019 |
| Molecular interactions of FG nucleoporin repeats at high resolution A Ibáñez de Opakua, JA Geraets, B Frieg, C Dienemann, A Savastano, ... Nature chemistry 14 (11), 1278-1285, 2022 | 20 | 2022 |
| Double Monoubiquitination Modifies the Molecular Recognition Properties of p15PAF Promoting Binding to the Reader Module of Dnmt1 A González-Magaña, AI De Opakua, N Merino, H Monteiro, T Diercks, ... ACS chemical biology 14 (10), 2315-2326, 2019 | 20 | 2019 |
| Proline/arginine dipeptide repeat polymers derail protein folding in amyotrophic lateral sclerosis M Babu, F Favretto, AI de Opakua, M Rankovic, S Becker, M Zweckstetter Nature Communications 12 (1), 3396, 2021 | 19 | 2021 |
| The p12 subunit of human polymerase δ uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA) A Gonzalez-Magaña, AI De Opakua, M Romano-Moreno, ... Journal of biological chemistry 294 (11), 3947-3956, 2019 | 19 | 2019 |
