| High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome S Alsford, DJ Turner, SO Obado, A Sanchez-Flores, L Glover, M Berriman, ... Genome research 21 (6), 915-924, 2011 | 513 | 2011 |
| High-throughput decoding of antitrypanosomal drug efficacy and resistance S Alsford, S Eckert, N Baker, L Glover, A Sanchez-Flores, KF Leung, ... Nature 482 (7384), 232-236, 2012 | 355 | 2012 |
| Tagging a T. brucei RRNA locus improves stable transfection efficiency and circumvents inducible expression position effects S Alsford, T Kawahara, L Glover, D Horn Molecular and biochemical parasitology 144 (2), 142-148, 2005 | 189 | 2005 |
| Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei S Alsford, D Horn Molecular and biochemical parasitology 161 (1), 76-79, 2008 | 165 | 2008 |
| A sirtuin in the African trypanosome is involved in both DNA repair and telomeric gene silencing but is not required for antigenic variation S Alsford, T Kawahara, C Isamah, D Horn Molecular microbiology 63 (3), 724-736, 2007 | 154 | 2007 |
| Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6 N Baker, S Alsford, D Horn Molecular and biochemical parasitology 176 (1), 55-57, 2011 | 135 | 2011 |
| NUP-1 Is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions KN DuBois, S Alsford, JM Holden, J Buisson, M Swiderski, JM Bart, ... PLoS biology 10 (3), e1001287, 2012 | 125 | 2012 |
| DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes L Glover, S Alsford, D Horn PLoS pathogens 9 (3), e1003260, 2013 | 117 | 2013 |
| VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes L Glover, S Hutchinson, S Alsford, D Horn Proceedings of the National Academy of Sciences 113 (26), 7225-7230, 2016 | 106 | 2016 |
| Trypanosomatid histones S Alsford, D Horn Molecular microbiology 53 (2), 365-372, 2004 | 92 | 2004 |
| Two essential MYST‐family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes T Kawahara, TN Siegel, AK Ingram, S Alsford, GAM Cross, D Horn Molecular microbiology 69 (4), 1054-1068, 2008 | 85 | 2008 |
| Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control L Glover, S Hutchinson, S Alsford, R McCulloch, MC Field, D Horn Cellular microbiology 15 (12), 1984-1993, 2013 | 74 | 2013 |
| Cell-cycle-regulated control of VSG expression site silencing by histones and histone chaperones ASF1A and CAF-1b in Trypanosoma brucei S Alsford, D Horn Nucleic acids research 40 (20), 10150-10160, 2012 | 74 | 2012 |
| Genetic dissection of drug resistance in trypanosomes SAM Alsford, JM Kelly, N Baker, D Horn Parasitology 140 (12), 1478-1491, 2013 | 69 | 2013 |
| Cyclic AMP effectors in African trypanosomes revealed by genome-scale RNA interference library screening for resistance to the phosphodiesterase inhibitor CpdA MK Gould, S Bachmaier, JAM Ali, S Alsford, DNA Tagoe, JC Munday, ... Antimicrobial agents and chemotherapy 57 (10), 4882-4893, 2013 | 65 | 2013 |
| Insights into antitrypanosomal drug mode-of-action from cytology-based profiling JA Thomas, N Baker, S Hutchinson, C Dominicus, A Trenaman, L Glover, ... PLoS neglected tropical diseases 12 (11), e0006980, 2018 | 62 | 2018 |
| Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes L Glover, S Alsford, N Baker, DJ Turner, A Sanchez-Flores, S Hutchinson, ... Nature protocols 10 (1), 106-133, 2015 | 60 | 2015 |
| Deletion of a trypanosome telomere leads to loss of silencing and progressive loss of terminal DNA in the absence of cell cycle arrest L Glover, S Alsford, C Beattie, D Horn Nucleic acids research 35 (3), 872-880, 2007 | 57 | 2007 |
| Segregation of minichromosomes in trypanosomes: implications for mitotic mechanisms K Gull, S Alsford, K Ersfeld Trends in microbiology 6 (8), 319-323, 1998 | 52 | 1998 |
| Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei JA Stortz, TD Serafim, S Alsford, J Wilkes, F Fernandez-Cortes, ... PLoS pathogens 13 (7), e1006477, 2017 | 51 | 2017 |
David HornUniversity of Dundee在 dundee.ac.uk 的电子邮件经过验证
