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Brent Derry
Brent Derry
Senior Scientist
在 sickkids.ca 的电子邮件经过验证 - 首页
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引用次数
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年份
Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death
MA Jordan, K Wendell, S Gardiner, W Brent Derry, H Copp, L Wilson
Cancer research 56 (4), 816, 1996
10761996
Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance
WB Derry, AP Putzke, JH Rothman
Science 294 (5542), 591-595, 2001
5852001
Panorama of ancient metazoan macromolecular complexes
C Wan, B Borgeson, S Phanse, F Tu, K Drew, G Clark, X Xiong, O Kagan, ...
Nature 525 (7569), 339-344, 2015
5422015
Substoichiometric binding of taxol suppresses microtubule dynamics
WB Derry, L Wilson, MA Jordan
Biochemistry 34 (7), 2203-2211, 1995
4671995
The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation
G Leprivier, M Remke, B Rotblat, A Dubuc, ARF Mateo, M Kool, ...
Cell 153 (5), 1064-1079, 2013
4422013
Taxol differentially modulates the dynamics of microtubules assembled from unfractionated and purified β-tubulin isotypes
WB Derry, L Wilson, IA Khan, RF Luduena, MA Jordan
Biochemistry 36 (12), 3554-3562, 1997
3281997
Biology of vascular malformations of the brain
Stroke 40 (12), e694-702, 2009
267*2009
Structure-function analysis of core STRIPAK Proteins: a signaling complex implicated in Golgi polarization
MJ Kean, DF Ceccarelli, M Goudreault, M Sanches, S Tate, B Larsen, ...
Journal of Biological Chemistry 286 (28), 25065-25075, 2011
1662011
Novel mechanism of resistance to paclitaxel (Taxol) in human K562 leukemia cells by combined selection with PSC 833.
JP Jaffrezou, C Dumontet, WB Derry, G Duran, KG Chen, E Tsuchiya, ...
Oncology research 7 (10-11), 517-527, 1995
1151995
CCM-3/STRIPAK promotes seamless tube extension through endocytic recycling
B Lant, B Yu, M Goudreault, D Holmyard, JDR Knight, P Xu, L Zhao, ...
Nature communications 6 (1), 1-13, 2015
982015
Low potency of taxol at microtubule minus ends: implications for its antimitotic and therapeutic mechanism
WB Derry, L Wilson, MA Jordan
Cancer research 58 (6), 1177-1184, 1998
841998
AKT-1 regulates DNA-damage-induced germline apoptosis in C. elegans
C Quevedo, DR Kaplan, WB Derry
Current biology 17 (3), 286-292, 2007
832007
Regulation of developmental rate and germ cell proliferation in Caenorhabditis elegans by the p53 gene network
WB Derry, R Bierings, M Van Iersel, T Satkunendran, V Reinke, ...
Cell Death & Differentiation 14 (4), 662-670, 2007
822007
CCM3/PDCD10 Heterodimerizes with Germinal Center Kinase III (GCKIII) Proteins Using a Mechanism Analogous to CCM3 Homodimerization*♦
DF Ceccarelli, RC Laister, VK Mulligan, MJ Kean, M Goudreault, IC Scott, ...
Journal of Biological Chemistry 286 (28), 25056-25064, 2011
792011
Structural differences in the DNA binding domains of human p53 and its C. elegans ortholog Cep-1
Y Huyen, PD Jeffrey, WB Derry, JH Rothman, NP Pavletich, ES Stavridi, ...
Structure 12 (7), 1237-1243, 2004
732004
Noncanonical control of C. elegans germline apoptosis by the insulin/IGF-1 and Ras/MAPK signaling pathways
AJ Perrin, M Gunda, B Yu, K Yen, S Ito, S Forster, HA Tissenbaum, ...
Cell Death & Differentiation 20 (1), 97-107, 2013
692013
CEP-1, the Caenorhabditis elegans p53 Homolog, Mediates Opposing Longevity Outcomes in Mitochondrial Electron Transport Chain Mutants
A Baruah, H Chang, M Hall, J Yuan, S Gordon, E Johnson, LL Shtessel, ...
PLoS genetics 10 (2), e1004097, 2014
672014
Essential embryonic roles of the CKI-1 cyclin-dependent kinase inhibitor in cell-cycle exit and morphogenesis in C. elegans
M Fukuyama, SB Gendreau, WB Derry, JH Rothman
Developmental Biology 260 (1), 273-286, 2003
672003
Cell-nonautonomous regulation of C. elegans germ cell death by kri-1
S Ito, S Greiss, A Gartner, WB Derry
Current Biology 20 (4), 333-338, 2010
592010
The SCFFSN-1 ubiquitin ligase controls germline apoptosis through CEP-1/p53 in C. elegans
MX Gao, EH Liao, B Yu, Y Wang, M Zhen, WB Derry
Cell Death & Differentiation 15 (6), 1054-1062, 2008
592008
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