| Host microbiota constantly control maturation and function of microglia in the CNS D Erny, ALH de Angelis, D Jaitin, P Wieghofer, O Staszewski, E David, ... Nature neuroscience 18 (7), 965, 2015 | 3030 | 2015 |
| Microglia emerge from erythromyeloid precursors via Pu. 1-and Irf8-dependent pathways K Kierdorf, D Erny, T Goldmann, V Sander, C Schulz, EG Perdiguero, ... Nature neuroscience 16 (3), 273, 2013 | 1579 | 2013 |
| Origin, fate and dynamics of macrophages at central nervous system interfaces T Goldmann, P Wieghofer, MJC Jordão, F Prutek, N Hagemeyer, ... Nature immunology 17 (7), 797, 2016 | 1076 | 2016 |
| A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation T Goldmann, P Wieghofer, PF Müller, Y Wolf, D Varol, S Yona, ... Nature neuroscience 16 (11), 1618, 2013 | 674 | 2013 |
| On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver I Theurl, I Hilgendorf, M Nairz, P Tymoszuk, D Haschka, M Asshoff, S He, ... Nature medicine 22 (8), 945, 2016 | 415 | 2016 |
| Self-renewing resident arterial macrophages arise from embryonic CX3CR1+ precursors and circulating monocytes immediately after birth S Ensan, A Li, R Besla, N Degousee, J Cosme, M Roufaiel, EA Shikatani, ... Nature immunology 17 (2), 159, 2016 | 371 | 2016 |
| Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models B Ajami, N Samusik, P Wieghofer, PP Ho, A Crotti, Z Bjornson, M Prinz, ... Nature neuroscience 21 (4), 541, 2018 | 309 | 2018 |
| A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation S Voet, C Guire, N Hagemeyer, A Martens, A Schroeder, P Wieghofer, ... Nature communications 9 (1), 2036, 2018 | 180 | 2018 |
| Transcriptome‐based profiling of yolk sac‐derived macrophages reveals a role for Irf8 in macrophage maturation N Hagemeyer, K Kierdorf, K Frenzel, J Xue, M Ringelhan, Z Abdullah, ... The EMBO journal 35 (16), 1730-1744, 2016 | 139 | 2016 |
| Genetic targeting of microglia P Wieghofer, KP Knobeloch, M Prinz Glia 63 (1), 1-22, 2015 | 126 | 2015 |
| Characterization of peripheral hematopoietic stem cells and monocytes in Parkinson's disease N Funk, P Wieghofer, S Grimm, R Schaefer, HJ Bühring, T Gasser, ... Movement Disorders 28 (3), 392-395, 2013 | 87 | 2013 |
| Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis C Mc Guire, L Elton, P Wieghofer, J Staal, S Voet, A Demeyer, D Nagel, ... Journal of neuroinflammation 11 (1), 124, 2014 | 84 | 2014 |
| Adipocyte death triggers a pro-inflammatory response and induces metabolic activation of resident macrophages A Lindhorst, N Raulien, P Wieghofer, J Eilers, F Rossi, I Bechmann, ... Cell death & disease 12 (6), 1-15, 2021 | 73 | 2021 |
| Paracaspase MALT1 deficiency protects mice from autoimmune-mediated demyelination C Mc Guire, P Wieghofer, L Elton, D Muylaert, M Prinz, R Beyaert, ... The Journal of Immunology 190 (6), 2896-2903, 2013 | 72 | 2013 |
| Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single‐cell profiling P Wieghofer, N Hagemeyer, R Sankowski, A Schlecht, O Staszewski, ... The EMBO journal 40 (6), e105123, 2021 | 71 | 2021 |
| A pain-mediated neural signal induces relapse in murine autoimmune encephalomyelitis, a multiple sclerosis model Y Arima, D Kamimura, T Atsumi, M Harada, T Kawamoto, N Nishikawa, ... Elife 4, e08733, 2015 | 70 | 2015 |
| Subretinal fibrosis in neovascular age-related macular degeneration: current concepts, therapeutic avenues, and future perspectives L Tenbrock, J Wolf, S Boneva, A Schlecht, H Agostini, P Wieghofer, ... Cell and tissue research, 1-15, 2021 | 69 | 2021 |
| Genetic manipulation of microglia during brain development and disease P Wieghofer, M Prinz Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (3), 299-309, 2016 | 57 | 2016 |
| Temporospatial distribution and transcriptional profile of retinal microglia in the oxygen‐induced retinopathy mouse model M Boeck, A Thien, J Wolf, N Hagemeyer, Y Laich, D Yusuf, R Backofen, ... Glia, 2020 | 53 | 2020 |
| Infiltration of circulating myeloid cells through CD95L contributes to neurodegeneration in mice L Gao, D Brenner, E Llorens-Bobadilla, G Saiz-Castro, T Frank, ... Journal of Experimental Medicine 212 (4), 469-480, 2015 | 46 | 2015 |
