A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model R Postina, A Schroeder, I Dewachter, J Bohl, U Schmitt, E Kojro, ... The Journal of clinical investigation 113 (10), 1456-1464, 2004 | 888 | 2004 |
Up‐regulation of the α‐secretase ADAM10 by retinoic acid receptors and acitretin F Tippmann, J Hundt, A Schneider, K Endres, F Fahrenholz The FASEB Journal 23 (6), 1643-1654, 2009 | 284 | 2009 |
Altered gut microbiome composition and tryptic activity of the 5xFAD Alzheimer’s mouse model C Brandscheid, F Schuck, S Reinhardt, KH Schäfer, CU Pietrzik, M Grimm, ... Journal of Alzheimer's Disease 56 (2), 775-788, 2017 | 265 | 2017 |
Oligodendrocyte precursor cells modulate the neuronal network by activity-dependent ectodomain cleavage of glial NG2 D Sakry, A Neitz, J Singh, R Frischknecht, D Marongiu, F Binamé, ... PLoS biology 12 (11), e1001993, 2014 | 196 | 2014 |
Tumor necrosis factor‐α converting enzyme is processed by proprotein‐convertases to its mature form which is degraded upon phorbol ester stimulation K Endres, A Anders, E Kojro, S Gilbert, F Fahrenholz, R Postina European journal of biochemistry 270 (11), 2386-2393, 2003 | 176 | 2003 |
Genomic structure and functional characterization of the human ADAM10 promoter C Prinzen, U Müller, K Endres, F Fahrenholz, R Postina The FASEB Journal 19 (11), 1522-1524, 2005 | 160 | 2005 |
How biological sex of the host shapes its gut microbiota F Valeri, K Endres Frontiers in Neuroendocrinology 61, 100912, 2021 | 148 | 2021 |
Increased CSF APPs-α levels in patients with Alzheimer disease treated with acitretin K Endres, F Fahrenholz, J Lotz, C Hiemke, S Teipel, K Lieb, O Tüscher, ... Neurology 83 (21), 1930-1935, 2014 | 135 | 2014 |
Unfolded protein response signaling by transcription factor XBP‐1 regulates ADAM10 and is affected in Alzheimer's disease S Reinhardt, F Schuck, S Grösgen, M Riemenschneider, T Hartmann, ... The FASEB Journal 28 (2), 978-997, 2014 | 114 | 2014 |
Shedding of the amyloid precursor protein‐like protein APLP2 by disintegrin‐metalloproteinases: Retinoic acid‐induced upregulation of substrate and proteinase ADAM10 during … K Endres, R Postina, A Schroeder, U Mueller, F Fahrenholz The FEBS journal 272 (22), 5808-5820, 2005 | 107 | 2005 |
Regulation of alpha-secretase ADAM10 expression and activity K Endres, F Fahrenholz Experimental brain research 217, 343-352, 2012 | 102 | 2012 |
Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10 R Augustin, K Endres, S Reinhardt, PH Kuhn, SF Lichtenthaler, J Hansen, ... BMC medical genetics 13, 1-12, 2012 | 100 | 2012 |
Upregulation of the α‐secretase ADAM10–risk or reason for hope? K Endres, F Fahrenholz The FEBS journal 277 (7), 1585-1596, 2010 | 99 | 2010 |
Vitamin D and its analogues decrease amyloid-β (Aβ) formation and increase Aβ-degradation MOW Grimm, A Thiel, AA Lauer, J Winkler, J Lehmann, L Regner, C Nelke, ... International journal of molecular sciences 18 (12), 2764, 2017 | 97 | 2017 |
Regulation of Alpha-Secretase ADAM10 In vitro and In vivo: Genetic, Epigenetic, and Protein-Based Mechanisms K Endres, T Deller Frontiers in molecular neuroscience 10, 56, 2017 | 97 | 2017 |
ADAM10 in Alzheimer's disease: Pharmacological modulation by natural compounds and its role as a peripheral marker PR Manzine, M Ettcheto, A Cano, O Busquets, E Marcello, S Pelucchi, ... Biomedicine & Pharmacotherapy 113, 108661, 2019 | 74 | 2019 |
ER-stress in Alzheimer’s disease: turning the scale? K Endres, S Reinhardt American journal of neurodegenerative disease 2 (4), 247, 2013 | 74 | 2013 |
Influence of commensal microbiota on the enteric nervous system and its role in neurodegenerative diseases K Endres, KH Schäfer Journal of innate immunity 10 (3), 172-180, 2018 | 69 | 2018 |
Oxidized docosahexaenoic acid species and lipid peroxidation products increase amyloidogenic amyloid precursor protein processing MOW Grimm, VJ Haupenthal, J Mett, CP Stahlmann, T Blümel, ... Neurodegenerative diseases 16 (1-2), 44-54, 2016 | 63 | 2016 |
A novel blood-brain barrier co-culture system for drug targeting of Alzheimer’s disease: establishment by using acitretin as a model drug C Freese, S Reinhardt, G Hefner, RE Unger, CJ Kirkpatrick, K Endres PloS one 9 (3), e91003, 2014 | 63 | 2014 |