What Makes a Bacterial Species Pathogenic?: Comparative Genomic Analysis of the Genus Leptospira DE Fouts, MA Matthias, H Adhikarla, B Adler, L Amorim-Santos, DE Berg, ... PLOS Negl Trop Dis 10 (2), e0004403, 2016 | 306 | 2016 |
The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis A Buschiazzo, MF Amaya, ML Cremona, AC Frasch, PM Alzari Molecular cell 10 (4), 757-768, 2002 | 295 | 2002 |
Trypanosoma c ruzi Trans-sialidase Operates through a Covalent Sialyl-Enzyme Intermediate: Tyrosine Is the Catalytic Nucleophile AG Watts, I Damager, ML Amaya, A Buschiazzo, P Alzari, AC Frasch, ... Journal of the American Chemical Society 125 (25), 7532-7533, 2003 | 282 | 2003 |
Structural insights into the catalytic mechanism of Trypanosoma cruzi trans-sialidase MF Amaya, AG Watts, I Damager, A Wehenkel, T Nguyen, A Buschiazzo, ... Structure 12 (5), 775-784, 2004 | 268 | 2004 |
Structural plasticity and catalysis regulation of a thermosensor histidine kinase D Albanesi, M Martín, F Trajtenberg, MC Mansilla, A Haouz, PM Alzari, ... Proceedings of the National Academy of Sciences 106 (38), 16185-16190, 2009 | 237 | 2009 |
Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation A Buschiazzo, JE Ugalde, ME Guerin, W Shepard, RA Ugalde, PM Alzari The EMBO journal 23 (16), 3196-3205, 2004 | 200 | 2004 |
Active nuclear import and cytoplasmic retention of activation-induced deaminase AM Patenaude, A Orthwein, Y Hu, VA Campo, B Kavli, A Buschiazzo, ... Nature structural & molecular biology 16 (5), 517-527, 2009 | 180 | 2009 |
Structural basis of sialyltransferase activity in trypanosomal sialidases A Buschiazzo, GA Tavares, O Campetella, S Spinelli, ML Cremona, ... The EMBO journal 19 (1), 16-24, 2000 | 168 | 2000 |
Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria ME Guerin, J Kordulakova, F Schaeffer, Z Svetlikova, A Buschiazzo, ... Journal of Biological Chemistry 282 (28), 20705-20714, 2007 | 155 | 2007 |
Identification of the gene (s) coding for the trans‐sialidase of Trypanosoma cruzi. AJ Parodi, GD Pollevick, M Mautner, A Buschiazzo, DO Sanchez, ... The EMBO journal 11 (5), 1705-1710, 1992 | 146 | 1992 |
A New Generation of Specific Trypanosoma cruzi trans‐Sialidase Inhibitors S Buchini, A Buschiazzo, SG Withers Angewandte Chemie International Edition 47 (14), 2700-2703, 2008 | 136 | 2008 |
Structural basis of lipid biosynthesis regulation in Gram‐positive bacteria GE Schujman, M Guerin, A Buschiazzo, F Schaeffer, LI Llarrull, G Reh, ... The EMBO journal 25 (17), 4074-4083, 2006 | 125 | 2006 |
Two-component sensing and regulation: How do histidine kinases talk with response regulators at the molecular level? A Buschiazzo, F Trajtenberg Annual review of microbiology 73, 507-528, 2019 | 120 | 2019 |
Phylogenetic analysis of bovine leukemia viruses isolated in South America reveals diversification in seven distinct genotypes G Moratorio, G Obal, A Dubra, A Correa, S Bianchi, A Buschiazzo, ... Archives of virology 155, 481-489, 2010 | 116 | 2010 |
Structural and kinetic analysis of two covalent sialosyl-enzyme intermediates on Trypanosoma rangeli sialidase AG Watts, P Oppezzo, SG Withers, PM Alzari, A Buschiazzo Journal of Biological Chemistry 281 (7), 4149-4155, 2006 | 116 | 2006 |
Crystal structure, catalytic mechanism, and mitogenic properties of Trypanosoma cruzi proline racemase A Buschiazzo, M Goytia, F Schaeffer, W Degrave, W Shepard, C Grégoire, ... Proceedings of the National Academy of Sciences of the United States of …, 2006 | 114 | 2006 |
Structural insights into sialic acid enzymology A Buschiazzo, PM Alzari Current opinion in chemical biology 12 (5), 565-572, 2008 | 113 | 2008 |
Data publication with the structural biology data grid supports live analysis PA Meyer, S Socias, J Key, E Ransey, EC Tjon, A Buschiazzo, M Lei, ... Nature Communications 7, 10882, 2016 | 109 | 2016 |
The High Resolution Structures of Free and Inhibitor-bound Trypanosoma rangeli Sialidase and its Comparison with T. cruziTrans-sialidase MF Amaya, A Buschiazzo, T Nguyen, PM Alzari Journal of molecular biology 325 (4), 773-784, 2003 | 96 | 2003 |
Discovery of novel inhibitors of Trypanosoma cruzitrans-sialidase from in silico screening J Neres, ML Brewer, L Ratier, H Botti, A Buschiazzo, PN Edwards, ... Bioorganic & medicinal chemistry letters 19 (3), 589-596, 2009 | 85 | 2009 |