Expression of the IAP protein family is dysregulated in pancreatic cancer cells and is important for resistance to chemotherapy RB Lopes, R Gangeswaran, IA McNeish, Y Wang, NR Lemoine International journal of cancer 120 (11), 2344-2352, 2007 | 289 | 2007 |
Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963 SH Thorne, THH Hwang, WE O’Gorman, DL Bartlett, S Sei, F Kanji, ... The Journal of clinical investigation 117 (11), 3350-3358, 2007 | 266 | 2007 |
Systemic delivery of oncolytic viruses: hopes and hurdles MS Ferguson, NR Lemoine, Y Wang Advances in virology 2012 (1), 805629, 2012 | 263 | 2012 |
Targeting of interferon-beta to produce a specific, multi-mechanistic oncolytic vaccinia virus DH Kirn, Y Wang, F Le Boeuf, J Bell, SH Thorne PLoS medicine 4 (12), e353, 2007 | 250 | 2007 |
Oncolytic viruses for cancer therapy: overcoming the obstacles HH Wong, NR Lemoine, Y Wang Viruses 2 (1), 78-106, 2010 | 215 | 2010 |
Analysis of gene expression in cancer cell lines identifies candidate markers for pancreatic tumorigenesis and metastasis E Missiaglia, E Blaveri, B Terris, YH Wang, E Costello, JP Neoptolemos, ... International journal of cancer 112 (1), 100-112, 2004 | 215 | 2004 |
E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models Y Wang, G Hallden, R Hill, A Anand, TC Liu, J Francis, G Brooks, ... Nature biotechnology 21 (11), 1328-1335, 2003 | 189 | 2003 |
Modulation of human dendritic-cell function following transduction with viral vectors: implications for gene therapy PH Tan, SC Beutelspacher, SA Xue, YH Wang, P Mitchell, JC McAlister, ... Blood 105 (10), 3824-3832, 2005 | 171 | 2005 |
Re-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent P Wang, X Li, J Wang, D Gao, Y Li, H Li, Y Chu, Z Zhang, H Liu, G Jiang, ... Nature communications 8 (1), 1395, 2017 | 159 | 2017 |
Novel immunocompetent murine tumor models for the assessment of replication-competent oncolytic adenovirus efficacy G Halldén, R Hill, Y Wang, A Anand, TC Liu, NR Lemoine, J Francis, ... Molecular Therapy 8 (3), 412-424, 2003 | 127 | 2003 |
Quantitative imaging of Na/I symporter transgene expression using positron emission tomography in the living animal T Groot-Wassink, EO Aboagye, Y Wang, NR Lemoine, AJ Reader, ... Molecular Therapy 9 (3), 436-442, 2004 | 125 | 2004 |
Supercritical antisolvent production of biodegradable micro-and nanoparticles for controlled delivery of paclitaxel LY Lee, CH Wang, KA Smith Journal of Controlled Release 125 (2), 96-106, 2008 | 124 | 2008 |
Enhancing poxvirus oncolytic effects through increased spread and immune evasion DH Kirn, Y Wang, W Liang, CH Contag, SH Thorne Cancer research 68 (7), 2071-2075, 2008 | 114 | 2008 |
Efficiently editing the vaccinia virus genome by using the CRISPR-Cas9 system M Yuan, W Zhang, J Wang, C Al Yaghchi, J Ahmed, L Chard, NR Lemoine, ... Journal of virology 89 (9), 5176-5179, 2015 | 109 | 2015 |
An E1B-19 kDa gene deletion mutant adenovirus demonstrates tumor necrosis factor-enhanced cancer selectivity and enhanced oncolytic potency TC Liu, G Hallden, Y Wang, G Brooks, J Francis, N Lemoine, D Kirn Molecular therapy 9 (6), 786-803, 2004 | 97 | 2004 |
The efficacy of oncolytic adenovirus is mediated by T-cell responses against virus and tumor in Syrian hamster model X Li, P Wang, H Li, X Du, M Liu, Q Huang, Y Wang, S Wang Clinical Cancer Research 23 (1), 239-249, 2017 | 89 | 2017 |
PRSS3 promotes tumour growth and metastasis of human pancreatic cancer G Jiang, F Cao, G Ren, D Gao, V Bhakta, Y Zhang, H Cao, Z Dong, ... Gut 59 (11), 1535-1544, 2010 | 87 | 2010 |
Lister strain of vaccinia virus armed with endostatin–angiostatin fusion gene as a novel therapeutic agent for human pancreatic cancer JR Tysome, A Briat, G Alusi, F Cao, D Gao, J Yu, P Wang, S Yang, Z Dong, ... Gene therapy 16 (10), 1223-1233, 2009 | 82 | 2009 |
Noninvasive imaging of the transcriptional activities of human telomerase promoter fragments in mice T Groot-Wassink, EO Aboagye, Y Wang, NR Lemoine, WN Keith, ... Cancer research 64 (14), 4906-4911, 2004 | 80 | 2004 |
Immunolipoplexes: an efficient, nonviral alternative for transfection of human dendritic cells with potential for clinical vaccination PH Tan, SC Beutelspacher, YH Wang, MO McClure, MA Ritter, ... Molecular Therapy 11 (5), 790-800, 2005 | 78 | 2005 |