Human herpes simplex virus: life cycle and development of inhibitors MK Kukhanova, AN Korovina, SN Kochetkov Biochemistry (Moscow) 79 (13), 1635-1652, 2014 | 247 | 2014 |
A novel action of human apurinic/apyrimidinic endonuclease: excision of L-configuration deoxyribonucleoside analogs from the 3′ termini of DNA KM Chou, M Kukhanova, YC Cheng Journal of Biological Chemistry 275 (40), 31009-31015, 2000 | 144 | 2000 |
2', 3'-Dideoxy-3'aminonucleoside 5'-triphosphates are the terminators of DNA synthesis catalyzed by DNA polymerases. ZG Chidgeavadze, RS Beabealashvilli, AM Atrazhev, MK Kukhanova, ... Nucleic acids research 12 (3), 1671, 1984 | 139 | 1984 |
l-and d-enantiomers of 2′, 3′-dideoxycytidine 5′-triphosphate analogs as substrates for human DNA polymerases: implications for the mechanism of toxicity M Kukhanova, SH Liu, D Mozzherin, TS Lin, CK Chu, YC Cheng Journal of Biological Chemistry 270 (39), 23055-23059, 1995 | 126 | 1995 |
Antiviral properties, metabolism, and pharmacokinetics of a novel azolo-1, 2, 4-triazine-derived inhibitor of influenza A and B virus replication I Karpenko, S Deev, O Kiselev, V Charushin, V Rusinov, E Ulomsky, ... Antimicrobial agents and chemotherapy 54 (5), 2017-2022, 2010 | 124 | 2010 |
Inhibition of Epstein-Barr virus replication by a novel l-nucleoside, 2′-fluoro-5-methyl-β-l-arabinofuranosyluracil GQ Yao, SH Liu, E Chou, M Kukhanova, CK Chu, YC Cheng Biochemical pharmacology 51 (7), 941-947, 1996 | 89 | 1996 |
The peptidyltransferase center of ribosomes AA Krayevsky, MK Kukhanova Progress in nucleic acid research and molecular biology 23, 1-51, 1980 | 86 | 1980 |
Development of the system ensuring a high-level expression of hepatitis C virus nonstructural NS5B and NS5A proteins AV Ivanov, AN Korovina, VL Tunitskaya, DA Kostyuk, VO Rechinsky, ... Protein expression and purification 48 (1), 14-23, 2006 | 81 | 2006 |
Metabolism of 2′, 3′-dideoxy-2′, 3′-didehydro-β-l (−)-5-fluorocytidine and its activity in combination with clinically approved anti-human immunodeficiency virus β-d (+ … GE Dutschman, EG Bridges, SH Liu, E Gullen, X Guo, M Kukhanova, ... Antimicrobial Agents and Chemotherapy 42 (7), 1799-1804, 1998 | 75 | 1998 |
DEAD-box RNA helicase DDX3: Functional properties and development of DDX3 inhibitors as antiviral and anticancer drugs MK Kukhanova, IL Karpenko, AV Ivanov Molecules 25 (4), 1015, 2020 | 72 | 2020 |
Design of anti-HIV compounds from nucleoside to nucleoside 5-triphosphate analogs. Problems and perspectives M Kukhanova, A Krayevsky, W Prusoff, YC Cheng Current pharmaceutical design 6 (5), 585-598, 2000 | 68 | 2000 |
Telomerase from human leukemia cells: properties and its interaction with deoxynucleoside analogues RB Pai, SB Pai, M Kukhanova, GE Dutschman, X Guo, YC Cheng Cancer research 58 (9), 1909-1913, 1998 | 67 | 1998 |
Nucleoside 5′-triphosphates with modified sugars as substrates for DNA polymerases ZG Chidgeavadze, RS Beabealashvilli, AA Krayevsky, MK Kukhanova Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 868 (2-3 …, 1986 | 65 | 1986 |
Nucleoside 5′-triphosphates modified at sugar residues as substrates for calf thymus terminal deoxynucleotidyl transferase and for AMV reverse transcriptase RS Beabealashvilli, AV Scamrov, TV Kutateladze, AM Mazo, ... Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 868 (2-3 …, 1986 | 62 | 1986 |
Properties of 2′, 3′-dideoxy-2′, 3′-dehydrothymidine 5′-triphosphate in terminating DNA synthesis catalyzed by several different DNA polymerases N Dyatkina, S Minassian, M Kukhanova, A Krayevsky, ... FEBS letters 219 (1), 151-155, 1987 | 55 | 1987 |
Carbocyclic dinucleoside polyphosphonates: Interaction with HIV reverse transcriptase and antiviral activity AL Khandazhinskaya, EA Shirokova, YS Skoblov, LS Victorova, ... Journal of medicinal chemistry 45 (6), 1284-1291, 2002 | 52 | 2002 |
Intracellular metabolism and pharmacokinetics of 5′-hydrogenphosphonate of 3′-azido-2′, 3′-dideoxythymidine, a prodrug of 3′-azido-2′, 3′-dideoxythymidine Y Skoblov, I Karpenko, E Shirokova, K Popov, V Andronova, G Galegov, ... Antiviral research 63 (2), 107-113, 2004 | 50 | 2004 |
Uncharged AZT and D4T derivatives of phosphonoformic and phosphonoacetic acids as anti-HIV pronucleosides EA Shirokova, MV Jasko, AL Khandazhinskaya, AV Ivanov, DV Yanvarev, ... Journal of medicinal chemistry 47 (14), 3606-3614, 2004 | 50 | 2004 |
Synthesis and antiherpetic activity of acyclovir phosphonates IL Karpenko, MV Jasko, VL Andronova, AV Ivanov, MK Kukhanova, ... Nucleosides, Nucleotides and Nucleic Acids 22 (3), 319-328, 2003 | 50 | 2003 |
1, 2, 4-Triazoloazine derivatives as a new type of herpes simplex virus inhibitors SL Deev, MV Yasko, IL Karpenko, AN Korovina, AL Khandazhinskaya, ... Bioorganic chemistry 38 (6), 265-270, 2010 | 47 | 2010 |