Killing mechanisms of chimeric antigen receptor (CAR) T cells MR Benmebarek, CH Karches, BL Cadilha, S Lesch, S Endres, S Kobold International journal of molecular sciences 20 (6), 1283, 2019 | 451 | 2019 |
Limitations in the design of chimeric antigen receptors for cancer therapy S Stoiber, BL Cadilha, MR Benmebarek, S Lesch, S Endres, S Kobold Cells 8 (5), 472, 2019 | 172 | 2019 |
T cells armed with CXC chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours S Lesch, V Blumenberg, S Stoiber, A Gottschlich, J Ogonek, BL Cadilha, ... Nature biomedical engineering 5 (11), 1246-1260, 2021 | 119 | 2021 |
Combined tumor-directed recruitment and protection from immune suppression enable CAR T cell efficacy in solid tumors BL Cadilha, MR Benmebarek, K Dorman, A Oner, T Lorenzini, H Obeck, ... Science advances 7 (24), eabi5781, 2021 | 83 | 2021 |
Determinants of response and resistance to CAR T cell therapy S Lesch, MR Benmebarek, BL Cadilha, S Stoiber, M Subklewe, S Endres, ... Seminars in Cancer Biology 65, 80-90, 2020 | 73 | 2020 |
Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin B Ruf, M Bruhns, S Babaei, N Kedei, L Ma, M Revsine, MR Benmebarek, ... Cell 186 (17), 3686-3705. e32, 2023 | 40 | 2023 |
Bispecific antibodies enable synthetic agonistic receptor-transduced T cells for tumor immunotherapy CH Karches, MR Benmebarek, ML Schmidbauer, M Kurzay, R Klaus, ... Clinical Cancer Research 25 (19), 5890-5900, 2019 | 39 | 2019 |
Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia A Gottschlich, M Thomas, R Grünmeier, S Lesch, L Rohrbacher, V Igl, ... Nature biotechnology 41 (11), 1618-1632, 2023 | 34 | 2023 |
A modular and controllable T cell therapy platform for acute myeloid leukemia MR Benmebarek, BL Cadilha, M Herrmann, S Lesch, S Schmitt, S Stoiber, ... Leukemia 35 (8), 2243-2257, 2021 | 29 | 2021 |
Paralysis of the cytotoxic granule machinery is a new cancer immune evasion mechanism mediated by chitinase 3-like-1 A Darwich, A Silvestri, MR Benmebarek, J Mouriès, B Cadilha, ... Journal for Immunotherapy of Cancer 9 (11), 2021 | 23 | 2021 |
Augmenting anti-CD19 and anti-CD22 CAR T-cell function using PD-1-CD28 checkpoint fusion proteins F Blaeschke, D Stenger, A Apfelbeck, BL Cadilha, MR Benmebarek, ... Blood Cancer Journal 11 (6), 108, 2021 | 21 | 2021 |
Impact of the selective A2AR and A2BR dual antagonist AB928/etrumadenant on CAR T cell function M Seifert, MR Benmebarek, D Briukhovetska, F Märkl, J Dörr, BL Cadilha, ... British Journal of Cancer 127 (12), 2175-2185, 2022 | 17 | 2022 |
CAR T cells targeting membrane-bound Hsp70 on tumor cells mimic Hsp70-primed NK cells A Bashiri Dezfouli, M Yazdi, MR Benmebarek, M Schwab, S Michaelides, ... Frontiers in immunology 13, 883694, 2022 | 17 | 2022 |
Chimeric antigen receptor T cells engineered to recognize the P329G-mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting … S Stock, MR Benmebarek, AK Kluever, D Darowski, C Jost, ... Journal for Immunotherapy of Cancer 10 (7), 2022 | 10 | 2022 |
Chimeric Antigen Receptor–Modified T Cells and T Cell–Engaging Bispecific Antibodies: Different Tools for the Same Job M Schwerdtfeger, MR Benmebarek, S Endres, M Subklewe, V Desiderio, ... Current hematologic malignancy reports 16 (2), 218-233, 2021 | 10 | 2021 |
Rational design of PD-1-CD28 immunostimulatory fusion proteins for CAR T cell therapy T Lorenzini, BL Cadilha, H Obeck, MR Benmebarek, F Märkl, ... British Journal of Cancer 129 (4), 696-705, 2023 | 6 | 2023 |
Adenosine A2a receptor inhibition increases the anti-tumor efficacy of anti-PD1 treatment in murine hepatobiliary cancers Y Myojin, JD McCallen, C Ma, KC Bauer, B Ruf, MR Benmebarek, ... JHEP Reports 6 (1), 100959, 2024 | 5 | 2024 |
Immunosuppressive CD29+ Treg accumulation in the liver in mice on checkpoint inhibitor therapy BL Green, Y Myojin, C Ma, B Ruf, L Ma, Q Zhang, U Rosato, J Qi, ... Gut 73 (3), 509-520, 2024 | 4 | 2024 |
Bispecific antibodies redirect synthetic agonistic receptor modified T cells against melanoma F Märkl, MR Benmebarek, J Keyl, BL Cadilha, M Geiger, C Karches, ... Journal for ImmunoTherapy of Cancer 11 (5), 2023 | 3 | 2023 |
The Gut Microbiome Controls Liver Tumors via the Vagus Nerve KC Bauer, R Trehan, B Ruf, Y Myojin, MR Benmebarek, C Ma, M Seifert, ... bioRxiv, 2024.01. 23.576951, 2024 | 2 | 2024 |