Facilitated anion transport induces hyperpolarization of the cell membrane that triggers differentiation and cell death in cancer stem cells V Soto-Cerrato, P Manuel-Manresa, E Hernando, S Calabuig-Farinas, ... Journal of the American Chemical Society 137 (50), 15892-15898, 2015 | 118 | 2015 |
The dopamine stabilizers ACR16 and (−)-OSU6162 display nanomolar affinities at the σ-1 receptor K Sahlholm, P Århem, K Fuxe, D Marcellino Molecular psychiatry 18 (1), 12-14, 2013 | 87 | 2013 |
Evidence for oligomerization between GABAB receptors and GIRK channels containing the GIRK1 and GIRK3 subunits F Ciruela, V Fernández‐Dueñas, K Sahlholm, L Fernández‐Alacid, ... European Journal of Neuroscience 32 (8), 1265-1277, 2010 | 65 | 2010 |
Pridopidine selectively occupies sigma-1 rather than dopamine D2 receptors at behaviorally active doses K Sahlholm, JWA Sijbesma, B Maas, C Kwizera, D Marcellino, ... Psychopharmacology 232, 3443-3453, 2015 | 64 | 2015 |
A Neanderthal sodium channel increases pain sensitivity in present-day humans H Zeberg, M Dannemann, K Sahlholm, K Tsuo, T Maricic, V Wiebe, ... Current Biology 30 (17), 3465-3469. e4, 2020 | 49 | 2020 |
The fast-off hypothesis revisited: A functional kinetic study of antipsychotic antagonism of the dopamine D2 receptor K Sahlholm, H Zeberg, J Nilsson, SO Ögren, K Fuxe, P Århem European Neuropsychopharmacology 26 (3), 467-476, 2016 | 49 | 2016 |
Behavioral control by striatal adenosine A2A‐dopamine D2 receptor heteromers J Taura, M Valle‐León, K Sahlholm, M Watanabe, K Van Craenenbroeck, ... Genes, Brain and Behavior 17 (4), e12432, 2018 | 40 | 2018 |
Voltage‐dependence of the human dopamine D2 receptor K Sahlholm, J Nilsson, D Marcellino, K Fuxe, P Århem Synapse 62 (6), 476-480, 2008 | 39 | 2008 |
Agonist-specific voltage sensitivity at the dopamine D2S receptor–molecular determinants and relevance to therapeutic ligands K Sahlholm, O Barchad-Avitzur, D Marcellino, M Gómez-Soler, K Fuxe, ... Neuropharmacology 61 (5-6), 937-949, 2011 | 37 | 2011 |
Voltage sensitivities and deactivation kinetics of histamine H3 and H4 receptors K Sahlholm, J Nilsson, D Marcellino, K Fuxe, P Århem Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (12), 3081-3089, 2012 | 35 | 2012 |
Antipsychotic-Like Efficacy of Dopamine D2 Receptor-Biased Ligands is Dependent on Adenosine A2A Receptor Expression K Sahlholm, M Gómez-Soler, M Valle-León, M López-Cano, JJ Taura, ... Molecular Neurobiology 55, 4952-4958, 2018 | 32 | 2018 |
Highly Selective Dopamine D3 Receptor Antagonists with Arylated Diazaspiro Alkane Cores SW Reilly, S Griffin, M Taylor, K Sahlholm, CC Weng, K Xu, DA Jacome, ... Journal of medicinal chemistry 60 (23), 9905-9910, 2017 | 32 | 2017 |
Decreased striatal adenosine A2A-dopamine D2 receptor heteromerization in schizophrenia M Valle-León, LF Callado, E Aso, MM Cajiao-Manrique, K Sahlholm, ... Neuropsychopharmacology 46 (3), 665-672, 2021 | 31 | 2021 |
Cocaine produces D2R-mediated conformational changes in the adenosine A2AR-dopamine D2R heteromer D Marcellino, G Navarro, K Sahlholm, J Nilsson, LF Agnati, EI Canela, ... Biochemical and Biophysical Research Communications 394 (4), 988-992, 2010 | 31 | 2010 |
A truncated Kv1.1 protein in the brain of the megencephalymouse: expression and interaction AS Persson, G Klement, M Almgren, K Sahlholm, J Nilsson, S Petersson, ... BMC neuroscience 6, 1-13, 2005 | 31 | 2005 |
Voltage-sensitivity at the human dopamine D2S receptor is agonist-specific K Sahlholm, D Marcellino, J Nilsson, K Fuxe, P Århem Biochemical and biophysical research communications 377 (4), 1216-1221, 2008 | 30 | 2008 |
G protein-gated inwardly rectifying potassium channel subunits 1 and 2 are down-regulated in rat dorsal root ganglion neurons and spinal cord after peripheral axotomy C Lyu, J Mulder, S Barde, K Sahlholm, H Zeberg, J Nilsson, P Århem, ... Molecular pain 11, s12990-015-0044-z, 2015 | 28 | 2015 |
Typical and atypical antipsychotics do not differ markedly in their reversibility of antagonism of the dopamine D2 receptor K Sahlholm, D Marcellino, J Nilsson, SO Ögren, K Fuxe, P Århem International Journal of Neuropsychopharmacology 17 (1), 149-155, 2014 | 28 | 2014 |
Differential voltage-sensitivity of D2-like dopamine receptors K Sahlholm, D Marcellino, J Nilsson, K Fuxe, P Århem Biochemical and biophysical research communications 374 (3), 496-501, 2008 | 28 | 2008 |
Remote local photoactivation of morphine produces analgesia without opioid‐related adverse effects M López‐Cano, J Font, E Aso, K Sahlholm, G Cabré, J Giraldo, ... British Journal of Pharmacology 180 (7), 958-974, 2023 | 22 | 2023 |