Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling E Brailoiu, D Churamani, X Cai, MG Schrlau, GC Brailoiu, X Gao, ... Journal of Cell Biology 186 (2), 201-209, 2009 | 463 | 2009 |
The cation/Ca2+ exchanger superfamily: phylogenetic analysis and structural implications X Cai, J Lytton Molecular Biology and Evolution 21 (9), 1692-1703, 2004 | 276 | 2004 |
CatSperζ regulates the structural continuity of sperm Ca2+ signaling domains and is required for normal fertility JJ Chung, K Miki, D Kim, SH Shim, HF Shi, JY Hwang, X Cai, Y Iseri, ... eLife 6, e23082, 2017 | 144 | 2017 |
An ancestral deuterostome family of two-pore channels mediates nicotinic acid adenine dinucleotide phosphate-dependent calcium release from acidic organelles E Brailoiu, R Hooper, X Cai, GC Brailoiu, MV Keebler, NJ Dun, ... Journal of Biological Chemistry 285 (5), 2897-2901, 2010 | 143 | 2010 |
Molecular cloning of a sixth member of the K+-dependent Na+/Ca2+ exchanger gene family, NCKX6 X Cai, J Lytton Journal of Biological Chemistry 279 (7), 5867-5876, 2004 | 139 | 2004 |
Molecular cloning of a third member of the potassium-dependent sodium-calcium exchanger gene family, NCKX3 A Kraev, BD Quednau, S Leach, XF Li, H Dong, R Winkfein, M Perizzolo, ... Journal of Biological Chemistry 276 (25), 23161-23172, 2001 | 125 | 2001 |
Evolutionary genomics reveals lineage-specific gene loss and rapid evolution of a sperm-specific ion channel complex: CatSpers and CatSperβ X Cai, DE Clapham PLoS One 3 (10), e3569, 2008 | 121 | 2008 |
Unicellular Ca2+ signaling ‘toolkit’at the origin of metazoa X Cai Molecular biology and evolution 25 (7), 1357-1361, 2008 | 117 | 2008 |
Two-pore channels provide insight into the evolution of voltage-gated Ca2+ and Na+ channels T Rahman, X Cai, GC Brailoiu, ME Abood, E Brailoiu, S Patel Science signaling 7 (352), ra109-ra109, 2014 | 116 | 2014 |
Ancestral Ca2+ signaling machinery in early animal and fungal evolution X Cai, DE Clapham Molecular biology and evolution 29 (1), 91-100, 2012 | 106 | 2012 |
Evolution of acidic Ca 2+ stores and their resident Ca 2+-permeable channels S Patel, X Cai Cell calcium 57 (3), 222-230, 2015 | 104 | 2015 |
Molecular evolution and structural analysis of the Ca 2+ release-activated Ca 2+ channel subunit, Orai X Cai Journal of molecular biology 368 (5), 1284-1291, 2007 | 82 | 2007 |
Tripartite motif containing protein 27 negatively regulates CD4 T cells by ubiquitinating and inhibiting the class II PI3K-C2β X Cai, S Srivastava, Y Sun, Z Li, H Wu, L Zuvela-Jelaska, J Li, ... Proceedings of the National Academy of Sciences 108 (50), 20072-20077, 2011 | 71 | 2011 |
Insights into the early evolution of animal calcium signaling machinery: A unicellular point of view X Cai, X Wang, S Patel, DE Clapham Cell calcium 57 (3), 166-173, 2015 | 70 | 2015 |
Regulation of the epithelial Ca2+ channel TRPV5 by reversible histidine phosphorylation mediated by NDPK-B and PHPT1 X Cai, S Srivastava, S Surindran, Z Li, EY Skolnik Molecular biology of the cell 25 (8), 1244-1250, 2014 | 66 | 2014 |
Degeneration of an intracellular ion channel in the primate lineage by relaxation of selective constraints X Cai, S Patel Molecular biology and evolution 27 (10), 2352-2359, 2010 | 66 | 2010 |
Regulation of smooth muscle cells in development and vascular disease: current therapeutic strategies X Cai Expert review of cardiovascular therapy 4 (6), 789-800, 2006 | 62 | 2006 |
Molecular evolution and functional divergence of the Ca 2+ sensor protein in store-operated Ca 2+ entry: stromal interaction molecule X Cai PLoS One 2 (7), e609, 2007 | 57 | 2007 |
Molecular evolution of the ankyrin gene family X Cai, Y Zhang Molecular biology and evolution 23 (3), 550-558, 2006 | 57 | 2006 |
Regulation of the platelet-derived growth factor receptor-β by G protein-coupled receptor kinase-5 in vascular smooth muscle cells involves the phosphatase Shp2 JH Wu, R Goswami, X Cai, ST Exum, X Huang, L Zhang, L Brian, ... Journal of Biological Chemistry 281 (49), 37758-37772, 2006 | 55 | 2006 |