Molecular Switch for Signal Transduction: Structural Differences Between Active and Inactive Forms of Protooncogenic ras Proteins MV Milburn, L Tong, AM DeVos, A Brünger, Z Yamaizumi, S Nishimura, ... Science 247 (4945), 939-945, 1990 | 1400 | 1990 |
Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site C Pargellis, L Tong, L Churchill, PF Cirillo, T Gilmore, AG Graham, ... Nature structural biology 9 (4), 268-272, 2002 | 1057 | 2002 |
Protein production and purification Architecture et Fonction des Macromolécules Biologiques Vincentelli Renaud 4 ... Nature methods 5 (2), 135-146, 2008 | 996 | 2008 |
Structural basis for signal transduction by the Toll/interleukin-1 receptor domains Y Xu, X Tao, B Shen, T Horng, R Medzhitov, JL Manley, L Tong Nature 408 (6808), 111-115, 2000 | 995 | 2000 |
Three-Dimensional Structure of an Oncogene Protein: Catalytic Domain of Human c-H-ras P21 AM De Vos, L Tong, MV Milburn, PM Matias, J Jancarik, S Noguchi, ... Science 239 (4842), 888-893, 1988 | 661 | 1988 |
Acetyl-coenzyme A carboxylase: crucial metabolic enzyme and attractive target for drug discovery L Tong Cellular and Molecular Life Sciences CMLS 62, 1784-1803, 2005 | 585 | 2005 |
Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease CR Mandel, S Kaneko, H Zhang, D Gebauer, V Vethantham, JL Manley, ... Nature 444 (7121), 953-956, 2006 | 547 | 2006 |
A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket L Tong, S Pav, DM White, S Rogers, KM Crane, CL Cywin, ML Brown, ... Nature structural biology 4 (4), 311-316, 1997 | 530 | 1997 |
Protein factors in pre-mRNA 3′-end processing CR Mandel, Y Bai, L Tong Cellular and Molecular Life Sciences 65, 1099-1122, 2008 | 524 | 2008 |
Structure and function of biotin-dependent carboxylases L Tong Cellular and Molecular Life Sciences 70, 863-891, 2013 | 461 | 2013 |
Structural basis for self-association and receptor recognition of human TRAF2 YC Park, V Burkitt, AR Villa, L Tong, H Wu Nature 398 (6727), 533-538, 1999 | 442 | 1999 |
Structural basis of the α1–β subunit interaction of voltage-gated Ca2+ channels Y Chen, M Li, Y Zhang, L He, Y Yamada, A Fitzmaurice, Y Shen, H Zhang, ... Nature 429 (6992), 675-680, 2004 | 436 | 2004 |
Pyrazole urea-based inhibitors of p38 MAP kinase: from lead compound to clinical candidate J Regan, S Breitfelder, P Cirillo, T Gilmore, AG Graham, E Hickey, B Klaus, ... Journal of medicinal chemistry 45 (14), 2994-3008, 2002 | 425 | 2002 |
Crystal structure of dimeric HIV-1 capsid protein C Momany, LC Kovari, AJ Prongay, W Keller, RK Gitti, BM Lee, ... Nature structural biology 3 (9), 763-770, 1996 | 400 | 1996 |
Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity F Forouhar, Y Yang, D Kumar, Y Chen, E Fridman, SW Park, Y Chiang, ... Proceedings of the National Academy of Sciences 102 (5), 1773-1778, 2005 | 388 | 2005 |
Structure of Sindbis virus core protein reveals a chymotrypsin-like serine proteinase and the organization of the virion HK Choi, L Tong, W Minor, P Dumas, U Boege, MG Rossmann, ... Nature 354 (6348), 37-43, 1991 | 379 | 1991 |
The locked rotation function L Tong, MG Rossmann Acta Crystallographica Section A: Foundations of Crystallography 46 (10 …, 1990 | 373 | 1990 |
Crystal structure of human DJ-1, a protein associated with early onset Parkinson's disease X Tao, L Tong Journal of Biological Chemistry 278 (33), 31372-31379, 2003 | 344 | 2003 |
Crystal structures at 2.2 Å resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP L Tong, AM de Vos, MV Milburn, SH Kim Journal of molecular biology 217 (3), 503-516, 1991 | 329 | 1991 |
[34] Rotation function calculations with GLRF program L Tong, MG Rossmann Methods in enzymology 276, 594-611, 1997 | 302 | 1997 |