Substituted spiro [2.3′] oxindolespiro [3.2 ″]-5, 6-dimethoxy-indane-1 ″-one-pyrrolidine analogue as inhibitors of acetylcholinesterase MA Ali, R Ismail, TS Choon, YK Yoon, AC Wei, S Pandian, RS Kumar, ... Bioorganic & medicinal chemistry letters 20 (23), 7064-7066, 2010 | 160 | 2010 |
Synthesis, characterization, and molecular docking analysis of novel benzimidazole derivatives as cholinesterase inhibitors YK Yoon, MA Ali, AC Wei, TS Choon, KY Khaw, V Murugaiyah, H Osman, ... Bioorganic chemistry 49, 33-39, 2013 | 89 | 2013 |
Benzimidazoles as new scaffold of sirtuin inhibitors: Green synthesis, in vitro studies, molecular docking analysis and evaluation of their anti-cancer properties YK Yoon, MA Ali, AC Wei, AN Shirazi, K Parang, TS Choon European journal of medicinal chemistry 83, 448-454, 2014 | 73 | 2014 |
Scopolamine, a toxin-induced experimental model, used for research in Alzheimer’s disease WN Chen, KY Yeong CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2020 | 72 | 2020 |
Butyrylcholinesterase: A Multifaceted Pharmacological Target and Tool ZY Ha, S Mathew, KY Yeong Current Protein and Peptide Science 21, 99-109, 2020 | 70 | 2020 |
Synthesis and evaluation of antimycobacterial activity of new benzimidazole aminoesters YK Yoon, MA Ali, AC Wei, TS Choon, R Ismail European journal of medicinal chemistry 93, 614-624, 2015 | 63 | 2015 |
Synthesis and evaluation of novel benzimidazole derivatives as sirtuin inhibitors with antitumor activities YK Yoon, MA Ali, AC Wei, TS Choon, H Osman, K Parang, AN Shirazi Bioorganic & Medicinal Chemistry 22 (2), 703-710, 2014 | 63 | 2014 |
A facile three-component [3+ 2]-cycloaddition for the regioselective synthesis of highly functionalised dispiropyrrolidines acting as antimycobacterial agents AC Wei, MA Ali, YK Yoon, R Ismail, TS Choon, RS Kumar Bioorganic & medicinal chemistry letters 23 (5), 1383-1386, 2013 | 59 | 2013 |
Benzimidazoles in drug discovery: a patent review CSW Law, KY Yeong ChemMedChem 16 (12), 1861-1877, 2021 | 50 | 2021 |
A patent review on the current developments of benzoxazoles in drug discovery XK Wong, KY Yeong ChemMedChem 16 (21), 3237-3262, 2021 | 48 | 2021 |
Antimycobacterial activity: A facile three-component [3+ 2]-cycloaddition for the regioselective synthesis of highly functionalised dispiropyrrolidines AC Wei, MA Ali, YK Yoon, R Ismail, TS Choon, RS Kumar, N Arumugam, ... Bioorganic & medicinal chemistry letters 22 (15), 4930-4933, 2012 | 46 | 2012 |
SIRT1 inhibition in pancreatic cancer models: contrasting effects in vitro and in vivo CE Oon, C Strell, KY Yeong, A Östman, J Prakash European journal of pharmacology 757, 59-67, 2015 | 45 | 2015 |
Antituberculosis: synthesis and antimycobacterial activity of novel benzimidazole derivatives Y Keng Yoon, M Ashraf Ali, TS Choon, R Ismail, A Chee Wei, ... BioMed research international 2013 (1), 926309, 2013 | 42 | 2013 |
In silico studies, synthesis and pharmacological evaluation to explore multi-targeted approach for imidazole analogues as potential cholinesterase inhibitors with … AS Gurjar, MN Darekar, KY Yeong, L Ooi Bioorganic & Medicinal Chemistry 26 (8), 1511-1522, 2018 | 33 | 2018 |
A rhodamine based chemosensor for solvent dependent chromogenic sensing of cobalt (II) and copper (II) ions with good selectivity and sensitivity: Synthesis, filter paper test … WC Chan, HM Saad, KS Sim, VS Lee, CW Ang, KY Yeong, KW Tan Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 262, 120099, 2021 | 31 | 2021 |
Discovery of gamma-mangostin from Garcinia mangostana as a potent and selective natural SIRT2 inhibitor KY Yeong, KY Khaw, Y Takahashi, Y Itoh, V Murugaiyah, T Suzuki Bioorganic Chemistry 94, 103403, 2020 | 31 | 2020 |
Anticancer activities of a benzimidazole compound through sirtuin inhibition in colorectal cancer YJ Tan, YT Lee, KY Yeong, SH Petersen, K Kono, SC Tan, CE Oon Future Medicinal Chemistry 10 (17), 2039-2057, 2018 | 31 | 2018 |
Current trends of benzothiazoles in drug discovery: A patent review (2015–2020) CSW Law, KY Yeong Expert Opinion on Therapeutic Patents 32 (3), 299-315, 2022 | 28 | 2022 |
Sirtuins and their implications in neurodegenerative diseases from a drug discovery perspective KY Yeong, N Berdigaliyev, Y Chang ACS chemical neuroscience 11 (24), 4073-4091, 2020 | 25 | 2020 |
Antituberculosis agents bearing the 1, 2-disubstituted benzimidazole scaffold KY Yeong, CW Ang, MA Ali, H Osman, SC Tan Medicinal Chemistry Research 26, 770-778, 2017 | 24 | 2017 |