Kinetic and structural characterization of the interaction between the FMN binding domain of cytochrome P450 reductase and cytochrome c R Huang, M Zhang, F Rwere, L Waskell, A Ramamoorthy Journal of Biological Chemistry 290 (8), 4843-4855, 2015 | 30 | 2015 |
SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant H Guo, X Yu, Y Liu, DT Paik, JM Justesen, M Chandy, JWS Jahng, ... Science translational medicine 15 (680), eabp9952, 2023 | 29 | 2023 |
Resonance Raman interrogation of the consequences of heme rotational disorder in myoglobin and its ligated derivatives F Rwere, PJ Mak, JR Kincaid Biochemistry 47 (48), 12869-12877, 2008 | 28 | 2008 |
Mutants of cytochrome P450 reductase lacking either Gly-141 or Gly-143 destabilize its FMN semiquinone F Rwere, C Xia, S Im, MM Haque, DJ Stuehr, L Waskell, JJP Kim Journal of Biological Chemistry 291 (28), 14639-14661, 2016 | 26 | 2016 |
Natural products for the treatment and management of diabetes mellitus in Zimbabwe-a review R Usai, S Majoni, F Rwere Frontiers in Pharmacology 13, 980819, 2022 | 25 | 2022 |
The impact of altered protein‐heme interactions on the resonance Raman spectra of heme proteins. Studies of heme rotational disorder F Rwere, PJ Mak, JR Kincaid Biopolymers: Original Research on Biomolecules 89 (3), 179-186, 2008 | 19 | 2008 |
Structural and kinetic studies of Asp632 mutants and fully reduced NADPH-cytochrome P450 oxidoreductase define the role of Asp632 loop dynamics in the control of NADPH binding … C Xia, F Rwere, S Im, AL Shen, L Waskell, JJP Kim Biochemistry 57 (6), 945-962, 2018 | 17 | 2018 |
Structural and functional characterization of a cytochrome P450 2B4 F429H mutant with an axial thiolate–histidine hydrogen bond Y Yang, H Zhang, D Usharani, W Bu, S Im, M Tarasev, F Rwere, NM Pearl, ... Biochemistry 53 (31), 5080-5091, 2014 | 16 | 2014 |
Resonance Raman determination of vinyl group disposition in different derivatives of native myoglobin and its heme‐disoriented form F Rwere, PJ Mak, JR Kincaid Journal of Raman Spectroscopy 45 (1), 97-104, 2014 | 16 | 2014 |
Phytochemical characterization and in vitro antibacterial activity of Xeroderris stuhlmannii (Taub.) Mendonca & EP Sousa bark extracts MA Selemani, LF Kazingizi, E Manzombe, LY Bishi, C Mureya, TT Gwata, ... South African Journal of Botany 142, 344-351, 2021 | 14 | 2021 |
A human TRPV1 genetic variant within the channel gating domain regulates pain sensitivity in rodents S He, VO Zambelli, P Sinharoy, L Brabenec, Y Bian, F Rwere, RCR Hell, ... The Journal of Clinical Investigation 133 (3), 2023 | 13 | 2023 |
A new preconcentration technique for the determination of PGMs and gold by fire assay and ICP-OES A Masasire, F Rwere, P Dzomba, M Mupa Journal of the Southern African Institute of Mining and Metallurgy 122 (1 …, 2022 | 7 | 2022 |
Inhibitory and in silico molecular docking of Xeroderris stuhlmannii (Taub.) Mendonca & EP Sousa phytochemical compounds on human α-glucosidases B Nyathi, JT Bvunzawabaya, CVP Mudawarima, E Manzombe, K Tsotsoro, ... Journal of Ethnopharmacology 312, 116501, 2023 | 5 | 2023 |
Influence of CYP2C19* 17 Genetic Polymorphism on the Steady-State Concentration of Escitalopram in Patients with Recurrent Depressive Disorder MS Zastrozhin, VY Skryabin, F Rwere, AE Petukhov, EP Pankratenko, ... Psychopharmacology Bulletin 52 (3), 8, 2022 | 4 | 2022 |
Aldehydes, aldehyde metabolism, and the ALDH2 consortium F Rwere, X Yu, CH Chen, ER Gross Biomolecules 12 (6), 763, 2022 | 4 | 2022 |
The FMN “140s Loop” of Cytochrome P450 Reductase Controls Electron Transfer to Cytochrome P450 F Rwere, S Im, L Waskell International Journal of Molecular Sciences 22 (19), 10625, 2021 | 4 | 2021 |
Antidiabetic and in silico molecular docking of Xeroderris stuhlmannii (Taub.) Mendonca & E.P. Sousa phytochemical compounds on human α-glucosidases B Nyathi, JT Bvunzawabaya, CVP Mudawarima, E Manzombe, K Tsotsoro, ... bioRxiv, 2022.09. 16.508336, 2022 | 3 | 2022 |
Phenotyping genetic differences in aldehyde dehydrogenase 2 after an alcohol challenge in humans JR White, F Rwere, X Zeng, L McNeil, K Zhou, MS Angst, CH Chen, ... medRxiv, 2020.06. 26.20137513, 2020 | 1 | 2020 |
A flexible linker of 8-amino acids between the membrane binding segment and the FMN domain of cytochrome P450 reductase is necessary for optimal activity F Rwere, NMP Cartee, Y Yang, L Waskell Journal of Inorganic Biochemistry 259, 112667, 2024 | | 2024 |
Uncovering newly identified aldehyde dehydrogenase 2 genetic variants that lead to acetaldehyde accumulation after an alcohol challenge F Rwere, JR White, RCR Hell, X Yu, X Zeng, L McNeil, KN Zhou, ... Journal of Translational Medicine 22 (1), 697, 2024 | | 2024 |