关注
Kyle E. Watters
Kyle E. Watters
Director, Arbor Biotechnologies
在 arbor.bio 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Systematic discovery of natural CRISPR-Cas12a inhibitors
KE Watters, C Fellmann, HB Bai, SM Ren, JA Doudna
Science 362 (6411), 236-239, 2018
2032018
Cotranscriptional folding of a riboswitch at nucleotide resolution
KE Watters, EJ Strobel, AM Yu, JT Lis, JB Lucks
Nature structural & molecular biology 23 (12), 1124-1131, 2016
1822016
A renaissance in RNA synthetic biology: new mechanisms, applications and tools for the future
J Chappell, KE Watters, MK Takahashi, JB Lucks
Current opinion in chemical biology 28, 47-56, 2015
1722015
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
K Kundert, JE Lucas, KE Watters, C Fellmann, AH Ng, BM Heineike, ...
Nature communications 10 (1), 2127, 2019
1702019
SHAPE-Seq 2.0: systematic optimization and extension of high-throughput chemical probing of RNA secondary structure with next generation sequencing
D Loughrey, KE Watters, AH Settle, JB Lucks
Nucleic acids research 42 (21), e165-e165, 2014
1592014
Broad-spectrum enzymatic inhibition of CRISPR-Cas12a
GJ Knott, BW Thornton, MJ Lobba, JJ Liu, B Al-Shayeb, KE Watters, ...
Nature structural & molecular biology 26 (4), 315-321, 2019
1122019
Comparative void-volume analysis of psychrophilic and mesophilic enzymes: structural bioinformatics of psychrophilic enzymes reveals sources of core flexibility
DI Paredes, K Watters, DJ Pitman, C Bystroff, JS Dordick
BMC structural biology 11, 1-9, 2011
992011
Simultaneous characterization of cellular RNA structure and function with in-cell SHAPE-Seq
KE Watters, TR Abbott, JB Lucks
Nucleic acids research 44 (2), e12-e12, 2016
942016
Characterizing RNA structures in vitro and in vivo with selective 2′-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)
KE Watters, MY Angela, EJ Strobel, AH Settle, JB Lucks
Methods 103, 34-48, 2016
922016
The centrality of RNA for engineering gene expression
J Chappell, MK Takahashi, S Meyer, D Loughrey, KE Watters, J Lucks
Biotechnology journal 8 (12), 1379-1395, 2013
912013
Machine learning predicts new anti-CRISPR proteins
S Eitzinger, A Asif, KE Watters, AT Iavarone, GJ Knott, JA Doudna, ...
Nucleic acids research 48 (9), 4698-4708, 2020
832020
RNA systems biology: uniting functional discoveries and structural tools to understand global roles of RNAs
EJ Strobel, KE Watters, D Loughrey, JB Lucks
Current opinion in biotechnology 39, 182-191, 2016
662016
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes
KE Watters, H Shivram, C Fellmann, RJ Lew, B McMahon, JA Doudna
Proceedings of the National Academy of Sciences 117 (12), 6531-6539, 2020
562020
Distributed biotin–streptavidin transcription roadblocks for mapping cotranscriptional RNA folding
EJ Strobel, KE Watters, Y Nedialkov, I Artsimovitch, JB Lucks
Nucleic acids research 45 (12), e109-e109, 2017
452017
Using in-cell SHAPE-Seq and simulations to probe structure–function design principles of RNA transcriptional regulators
MK Takahashi, KE Watters, PM Gasper, TR Abbott, PD Carlson, AA Chen, ...
RnA 22 (6), 920-933, 2016
382016
Probing of RNA structures in a positive sense RNA virus reveals selection pressures for structural elements
KE Watters, K Choudhary, S Aviran, JB Lucks, KL Perry, JR Thompson
Nucleic acids research 46 (5), 2573-2584, 2018
292018
Mapping RNA structure in vitro with SHAPE chemistry and next-generation sequencing (SHAPE-Seq)
KE Watters, JB Lucks
RNA Structure Determination: Methods and Protocols, 135-162, 2016
222016
The CRISPR revolution and its potential impact on global health security
KE Watters, J Kirkpatrick, MJ Palmer, GD Koblentz
Pathogens and global health 115 (2), 80-92, 2021
16*2021
Computationally reconstructing cotranscriptional RNA folding pathways from experimental data reveals rearrangement of non-native folding intermediates
AM Yu, PM Gasper, EJ Strobel, KE Watters, AA Chen, JB Lucks
bioRxiv, 379222, 2018
92018
Proteins that inhibit cas12a (cpf1), a cripr-cas nuclease
N Blackburn-Marino, J Bondy-Denomy, KE Watters, JA Doudna
US Patent App. 17/252,947, 2021
12021
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