Systematic discovery of natural CRISPR-Cas12a inhibitors KE Watters, C Fellmann, HB Bai, SM Ren, JA Doudna Science 362 (6411), 236-239, 2018 | 203 | 2018 |
Cotranscriptional folding of a riboswitch at nucleotide resolution KE Watters, EJ Strobel, AM Yu, JT Lis, JB Lucks Nature structural & molecular biology 23 (12), 1124-1131, 2016 | 182 | 2016 |
A renaissance in RNA synthetic biology: new mechanisms, applications and tools for the future J Chappell, KE Watters, MK Takahashi, JB Lucks Current opinion in chemical biology 28, 47-56, 2015 | 172 | 2015 |
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs K Kundert, JE Lucas, KE Watters, C Fellmann, AH Ng, BM Heineike, ... Nature communications 10 (1), 2127, 2019 | 170 | 2019 |
SHAPE-Seq 2.0: systematic optimization and extension of high-throughput chemical probing of RNA secondary structure with next generation sequencing D Loughrey, KE Watters, AH Settle, JB Lucks Nucleic acids research 42 (21), e165-e165, 2014 | 159 | 2014 |
Broad-spectrum enzymatic inhibition of CRISPR-Cas12a GJ Knott, BW Thornton, MJ Lobba, JJ Liu, B Al-Shayeb, KE Watters, ... Nature structural & molecular biology 26 (4), 315-321, 2019 | 112 | 2019 |
Comparative void-volume analysis of psychrophilic and mesophilic enzymes: structural bioinformatics of psychrophilic enzymes reveals sources of core flexibility DI Paredes, K Watters, DJ Pitman, C Bystroff, JS Dordick BMC structural biology 11, 1-9, 2011 | 99 | 2011 |
Simultaneous characterization of cellular RNA structure and function with in-cell SHAPE-Seq KE Watters, TR Abbott, JB Lucks Nucleic acids research 44 (2), e12-e12, 2016 | 94 | 2016 |
Characterizing RNA structures in vitro and in vivo with selective 2′-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq) KE Watters, MY Angela, EJ Strobel, AH Settle, JB Lucks Methods 103, 34-48, 2016 | 92 | 2016 |
The centrality of RNA for engineering gene expression J Chappell, MK Takahashi, S Meyer, D Loughrey, KE Watters, J Lucks Biotechnology journal 8 (12), 1379-1395, 2013 | 91 | 2013 |
Machine learning predicts new anti-CRISPR proteins S Eitzinger, A Asif, KE Watters, AT Iavarone, GJ Knott, JA Doudna, ... Nucleic acids research 48 (9), 4698-4708, 2020 | 83 | 2020 |
RNA systems biology: uniting functional discoveries and structural tools to understand global roles of RNAs EJ Strobel, KE Watters, D Loughrey, JB Lucks Current opinion in biotechnology 39, 182-191, 2016 | 66 | 2016 |
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes KE Watters, H Shivram, C Fellmann, RJ Lew, B McMahon, JA Doudna Proceedings of the National Academy of Sciences 117 (12), 6531-6539, 2020 | 56 | 2020 |
Distributed biotin–streptavidin transcription roadblocks for mapping cotranscriptional RNA folding EJ Strobel, KE Watters, Y Nedialkov, I Artsimovitch, JB Lucks Nucleic acids research 45 (12), e109-e109, 2017 | 45 | 2017 |
Using in-cell SHAPE-Seq and simulations to probe structure–function design principles of RNA transcriptional regulators MK Takahashi, KE Watters, PM Gasper, TR Abbott, PD Carlson, AA Chen, ... RnA 22 (6), 920-933, 2016 | 38 | 2016 |
Probing of RNA structures in a positive sense RNA virus reveals selection pressures for structural elements KE Watters, K Choudhary, S Aviran, JB Lucks, KL Perry, JR Thompson Nucleic acids research 46 (5), 2573-2584, 2018 | 29 | 2018 |
Mapping RNA structure in vitro with SHAPE chemistry and next-generation sequencing (SHAPE-Seq) KE Watters, JB Lucks RNA Structure Determination: Methods and Protocols, 135-162, 2016 | 22 | 2016 |
The CRISPR revolution and its potential impact on global health security KE Watters, J Kirkpatrick, MJ Palmer, GD Koblentz Pathogens and global health 115 (2), 80-92, 2021 | 16* | 2021 |
Computationally reconstructing cotranscriptional RNA folding pathways from experimental data reveals rearrangement of non-native folding intermediates AM Yu, PM Gasper, EJ Strobel, KE Watters, AA Chen, JB Lucks bioRxiv, 379222, 2018 | 9 | 2018 |
Proteins that inhibit cas12a (cpf1), a cripr-cas nuclease N Blackburn-Marino, J Bondy-Denomy, KE Watters, JA Doudna US Patent App. 17/252,947, 2021 | 1 | 2021 |