Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10692 | 2021 |
Marilines A–C: Novel Phthalimidines from the Sponge‐Derived Fungus Stachylidium sp. C Almeida, Y Hemberger, SM Schmitt, S Bouhired, L Natesan, S Kehraus, ... Chemistry–A European Journal 18 (28), 8827-8834, 2012 | 76 | 2012 |
Small‐molecule inhibitors of multidrug resistance‐associated protein 1 and related processes: A historic approach and recent advances SM Stefan, M Wiese Medicinal Research Reviews 39 (1), 176-264, 2019 | 72 | 2019 |
9-Deazapurines as broad-spectrum inhibitors of the ABC transport proteins P-glycoprotein, multidrug resistance-associated protein 1, and breast cancer resistance protein K Stefan, SM Schmitt, M Wiese Journal of medicinal chemistry 60 (21), 8758-8780, 2017 | 62 | 2017 |
Multi-target ABC transporter modulators: what next and where to go? SM Stefan Future Medicinal Chemistry 11 (18), 2353-2358, 2019 | 57 | 2019 |
Pyrrolopyrimidine derivatives as novel inhibitors of multidrug resistance-associated protein 1 (MRP1, ABCC1) SM Schmitt, K Stefan, M Wiese Journal of medicinal chemistry 59 (7), 3018-3033, 2016 | 49 | 2016 |
Novel chalcone and flavone derivatives as selective and dual inhibitors of the transport proteins ABCB1 and ABCG2 K Silbermann, CP Shah, NU Sahu, K Juvale, SM Stefan, PS Kharkar, ... European Journal of Medicinal Chemistry 164, 193-213, 2019 | 43 | 2019 |
Identification of thienopyrimidine scaffold as an inhibitor of the ABC transport protein ABCC1 (MRP1) and related transporters using a combined virtual screening approach K Silbermann, SM Stefan, R Elshawadfy, V Namasivayam, M Wiese Journal of Medicinal Chemistry 62 (9), 4383-4400, 2019 | 33 | 2019 |
The A‐B‐C of small‐molecule ABC transport protein modulators: From inhibition to activation—a case study of multidrug resistance‐associated protein 1 (ABCC1) M Wiese, SM Stefan Medicinal Research Reviews 39 (6), 2031-2081, 2019 | 29 | 2019 |
Pyrrolopyrimidine derivatives and purine analogs as novel activators of Multidrug Resistance-associated Protein 1 (MRP1, ABCC1) SM Schmitt, K Stefan, M Wiese Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (1), 69-79, 2017 | 26 | 2017 |
C@ PA: computer-aided pattern analysis to predict multitarget ABC transporter inhibitors V Namasivayam, K Silbermann, M Wiese, J Pahnke, SM Stefan Journal of Medicinal Chemistry 64 (6), 3350-3366, 2021 | 25 | 2021 |
Superior pyrimidine derivatives as selective ABCG2 inhibitors and broad-spectrum ABCB1, ABCC1, and ABCG2 antagonists K Silbermann, J Li, V Namasivayam, F Baltes, G Bendas, SM Stefan, ... Journal of Medicinal Chemistry 63 (18), 10412-10432, 2020 | 25 | 2020 |
Physicochemistry shapes bioactivity landscape of pan-ABC transporter modulators: anchor point for innovative Alzheimer's disease therapeutics V Namasivayam, K Stefan, L Gorecki, J Korabecny, O Soukup, ... International Journal of Biological Macromolecules 217, 775-791, 2022 | 22 | 2022 |
Strategies to gain novel Alzheimer’s disease diagnostics and therapeutics using modulators of ABCA transporters J Pahnke, P Bascuñana, M Brackhan, K Stefan, V Namasivayam, ... Free neuropathology 2, 2021 | 20 | 2021 |
The growing evidence for targeting P-glycoprotein in lysosomes to overcome resistance SM Stefan, PJ Jansson, DS Kalinowski, R Anjum, M Dharmasivam, ... Future Medicinal Chemistry 12 (6), 473-477, 2020 | 20 | 2020 |
Structural feature-driven pattern analysis for multitarget modulator landscapes V Namasivayam, K Stefan, K Silbermann, J Pahnke, M Wiese, SM Stefan Bioinformatics 38 (5), 1385-1392, 2022 | 19 | 2022 |
Rational drug design of 6-substituted 4-anilino-2-phenylpyrimidines for exploration of novel ABCG2 binding site K Silbermann, J Li, V Namasivayam, SM Stefan, M Wiese European Journal of Medicinal Chemistry 212, 113045, 2021 | 19 | 2021 |
Scaffold fragmentation and substructure hopping reveal potential, robustness, and limits of computer-aided pattern analysis (C@ PA) V Namasivayam, K Silbermann, J Pahnke, M Wiese, SM Stefan Computational and structural biotechnology journal 19, 3269-3283, 2021 | 18 | 2021 |
Indole derivatives as new structural class of potent and antiproliferative inhibitors of monocarboxylate transporter 1 (MCT1; SLC16A1) S Puri, K Stefan, SL Khan, J Pahnke, SM Stefan, K Juvale Journal of Medicinal Chemistry 66 (1), 657-676, 2022 | 17 | 2022 |
A curated binary pattern multitarget dataset of focused ATP-binding cassette transporter inhibitors SM Stefan, PJ Jansson, J Pahnke, V Namasivayam Scientific Data 9 (1), 446, 2022 | 17 | 2022 |