Allergic airway disease is unaffected by the absence of IL-4Rα–dependent alternatively activated macrophages NE Nieuwenhuizen, F Kirstein, J Jayakumar, B Emedi, R Hurdayal, ... Journal of Allergy and Clinical Immunology 130 (3), 743-750. e8, 2012 | 72 | 2012 |
Differential responses to natural and recombinant allergens in a murine model of fish allergy ML van der Ventel, NE Nieuwenhuizen, F Kirstein, C Hikuam, ... Molecular immunology 48 (4), 637-646, 2011 | 67 | 2011 |
B cells that produce immunoglobulin E mediate colitis in BALB/c mice JC Hoving, F Kirstein, NE Nieuwenhuizen, LCE Fick, E Hobeika, M Reth, ... Gastroenterology 142 (1), 96-108, 2012 | 58 | 2012 |
The M3 muscarinic receptor is required for optimal adaptive immunity to helminth and bacterial infection M Darby, C Schnoeller, A Vira, F Culley, S Bobat, E Logan, F Kirstein, ... PLoS pathogens 11 (1), e1004636, 2015 | 55 | 2015 |
Microbial ligand costimulation drives neutrophilic steroid-refractory asthma S Hadebe, F Kirstein, K Fierens, K Chen, RA Drummond, S Vautier, ... PLoS One 10 (8), e0134219, 2015 | 47 | 2015 |
IL-4Rα-Associated Antigen Processing by B Cells Promotes Immunity in Nippostrongylus brasiliensis Infection WGC Horsnell, MG Darby, JC Hoving, N Nieuwenhuizen, HJ McSorley, ... PLoS pathogens 9 (10), e1003662, 2013 | 44 | 2013 |
IL-4Rα-responsive smooth muscle cells contribute to initiation of TH2 immunity and pulmonary pathology in Nippostrongylus brasiliensis infections WGC Horsnell, A Vira, F Kirstein, H Mearns, JC Hoving, AJ Cutler, ... Mucosal immunology 4 (1), 83-92, 2011 | 41 | 2011 |
Expression of IL-4 receptor α on smooth muscle cells is not necessary for development of experimental allergic asthma F Kirstein, WGC Horsnell, DA Kuperman, X Huang, DJ Erle, AL Lopata, ... Journal of Allergy and Clinical Immunology 126 (2), 347-354, 2010 | 38 | 2010 |
Interleukin-4-Promoted T Helper 2 Responses Enhance Nippostrongylus brasiliensis-Induced Pulmonary Pathology H Mearns, WGC Horsnell, JC Hoving, B Dewals, AJ Cutler, F Kirstein, ... Infection and immunity 76 (12), 5535-5542, 2008 | 36 | 2008 |
β-Glucan exacerbates allergic airway responses to house dust mite allergen S Hadebe, F Kirstein, K Fierens, P Redelinghuys, GI Murray, DL Williams, ... Respiratory research 17, 1-3, 2016 | 31 | 2016 |
Role of IL-4 receptor α–positive CD4+ T cells in chronic airway hyperresponsiveness F Kirstein, NE Nieuwenhuizen, J Jayakumar, WGC Horsnell, ... Journal of Allergy and Clinical Immunology 137 (6), 1852-1862. e9, 2016 | 30 | 2016 |
Anisakis pegreffii-Induced Airway Hyperresponsiveness Is Mediated by Gamma Interferon in the Absence of Interleukin-4 Receptor Alpha Responsiveness F Kirstein, WGC Horsnell, N Nieuwenhuizen, B Ryffel, AL Lopata, ... Infection and Immunity 78 (9), 4077-4086, 2010 | 30 | 2010 |
Investigation of in vitro and in vivo anti-asthmatic properties of Siphonochilus aethiopicus G Fouche, N Nieuwenhuizen, V Maharaj, S van Rooyen, N Harding, ... Journal of ethnopharmacology 133 (2), 843-849, 2011 | 25 | 2011 |
Occupational allergy to latex among loom tuners in a textile factory AL Lopata, S Adams, F Kirstein, N Henwood, M Raulf-Heimsoth, ... International archives of allergy and immunology 144 (1), 64-68, 2007 | 18 | 2007 |
IL-4Rα signaling in CD4+ CD25+ FoxP3+ T regulatory cells restrains airway inflammation via limiting local tissue IL-33 J Khumalo, F Kirstein, S Hadebe, F Brombacher JCI insight 5 (20), 2020 | 17 | 2020 |
Therapeutic and prophylactic deletion of IL‐4Ra‐signaling ameliorates established ovalbumin induced allergic asthma J Khumalo, F Kirstein, M Scibiorek, S Hadebe, F Brombacher Allergy 75 (6), 1347-1360, 2020 | 15 | 2020 |
House dust mite induced allergic airway disease is attenuated in CD11ccreIL-4Rα−/l°x mice NE Nieuwenhuizen, F Kirstein, JC Hoving, F Brombacher Scientific reports 8 (1), 885, 2018 | 15 | 2018 |
Interruption of CD28-mediated costimulation during allergen challenge protects mice from allergic airway disease T Gogishvili, F Lühder, F Kirstein, NE Nieuwenhuizen, S Goebbels, ... Journal of allergy and clinical immunology 130 (6), 1394-1403. e4, 2012 | 14 | 2012 |
Deletion of IL-4Rα signaling on B cells limits hyperresponsiveness depending on antigen load S Hadebe, J Khumalo, S Mangali, N Mthembu, H Ndlovu, M Scibiorek, ... Journal of Allergy and Clinical Immunology 148 (1), 99-109. e5, 2021 | 11 | 2021 |
Associations between environmental dust composition and atopic dermatitis in urban and rural settings T Trikamjee, W Basera, M Botha, HE Facey‐Thomas, B Gaunt, J Genuneit, ... Pediatric Allergy and Immunology 32 (5), 1013-1021, 2021 | 10 | 2021 |