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Ketan Patel
Ketan Patel
未知所在单位机构
在 mrc-lmb.cam.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
Involvement of Brca2 in DNA repair
KJ Patel, PCC Veronica, H Lee, A Corcoran, FC Thistlethwaite, MJ Evans, ...
Molecular cell 1 (3), 347-357, 1998
7931998
The emerging genetic and molecular basis of Fanconi anaemia
H Joenje, KJ Patel
Nature Reviews Genetics 2 (6), 446-458, 2001
7442001
Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice
F Langevin, GP Crossan, IV Rosado, MJ Arends, KJ Patel
Nature 475 (7354), 53-58, 2011
5512011
Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function
JI Garaycoechea, GP Crossan, F Langevin, M Daly, MJ Arends, KJ Patel
Nature 489 (7417), 571-575, 2012
4162012
The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair
W Niedzwiedz, G Mosedale, M Johnson, CY Ong, P Pace, KJ Patel
Molecular cell 15 (4), 607-620, 2004
3972004
Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells
JI Garaycoechea, GP Crossan, F Langevin, L Mulderrig, S Louzada, ...
Nature 553 (7687), 171-177, 2018
3812018
Endogenous formaldehyde is a hematopoietic stem cell genotoxin and metabolic carcinogen
LB Pontel, IV Rosado, G Burgos-Barragan, JI Garaycoechea, R Yu, ...
Molecular cell 60 (1), 177-188, 2015
3522015
Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism
G Burgos-Barragan, N Wit, J Meiser, FA Dingler, M Pietzke, L Mulderrig, ...
Nature 548 (7669), 549-554, 2017
3042017
Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway
P Pace, G Mosedale, MR Hodskinson, IV Rosado, M Sivasubramaniam, ...
Science 329 (5988), 219-223, 2010
2732010
Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia
GP Crossan, L van der Weyden, IV Rosado, F Langevin, PHL Gaillard, ...
Nature genetics 43 (2), 147-152, 2011
2412011
Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI
AF Alpi, PE Pace, MM Babu, KJ Patel
Molecular cell 32 (6), 767-777, 2008
2352008
FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA
P Sarkies, P Murat, LG Phillips, KJ Patel, S Balasubramanian, JE Sale
Nucleic acids research 40 (4), 1485-1498, 2012
2262012
The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway
G Mosedale, W Niedzwiedz, A Alpi, F Perrina, JB Pereira-Leal, ...
Nature structural & molecular biology 12 (9), 763-771, 2005
2262005
Deubiquitination of FANCD2 is required for DNA crosslink repair
VH Oestergaard, F Langevin, HJ Kuiken, P Pace, W Niedzwiedz, ...
Molecular cell 28 (5), 798-809, 2007
2172007
Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway
IV Rosado, F Langevin, GP Crossan, M Takata, KJ Patel
Nature structural & molecular biology 18 (12), 1432-1434, 2011
2122011
FANCE: the link between Fanconi anaemia complex assembly and activity
P Pace, M Johnson, WM Tan, G Mosedale, C Sng, M Hoatlin, J De Winter, ...
The EMBO journal 21 (13), 3414-3423, 2002
2042002
TRAIP is a master regulator of DNA interstrand crosslink repair
RA Wu, DR Semlow, AN Kamimae-Lanning, OV Kochenova, G Chistol, ...
Nature 567 (7747), 267-272, 2019
1812019
Why does the bone marrow fail in Fanconi anemia?
JI Garaycoechea, KJ Patel
Blood 123 (1), 26-34, 2014
1812014
BRCA1-independent ubiquitination of FANCD2
CJ Vandenberg, F Gergely, CY Ong, P Pace, DL Mallery, K Hiom, ...
Molecular cell 12 (1), 247-254, 2003
1782003
Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair
MRG Hodskinson, J Silhan, GP Crossan, JI Garaycoechea, S Mukherjee, ...
Molecular cell 54 (3), 472-484, 2014
1642014
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