| PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage SL Rulten, A Rotheray, RL Green, GJ Grundy, DAQ Moore, ... Nucleic acids research 42 (1), 307-314, 2014 | 206 | 2014 |
| The structure of human CD23 and its interactions with IgE and CD21 RG Hibbert, P Teriete, GJ Grundy, RL Beavil, R Reljić, VM Holers, ... The Journal of experimental medicine 202 (6), 751, 2005 | 195 | 2005 |
| APLF promotes the assembly and activity of non‐homologous end joining protein complexes GJ Grundy, SL Rulten, Z Zeng, R Arribas‐Bosacoma, N Iles, K Manley, ... The EMBO journal 32 (1), 112-125, 2013 | 181 | 2013 |
| Soluble CD23 monomers inhibit and oligomers stimulate IGE synthesis in human B cells N McCloskey, J Hunt, RL Beavil, MR Jutton, GJ Grundy, E Girardi, ... Journal of Biological Chemistry 282 (33), 24083-24091, 2007 | 111 | 2007 |
| Characterization of human complement receptor type 2 (CR2/CD21) as a receptor for IFN-α: a potential role in systemic lupus erythematosus R Asokan, J Hua, KA Young, HJ Gould, JP Hannan, DM Kraus, ... The Journal of Immunology 177 (1), 383-394, 2006 | 111 | 2006 |
| One ring to bring them all—the role of Ku in mammalian non-homologous end joining GJ Grundy, HA Moulding, KW Caldecott, SL Rulten DNA repair 17, 30-38, 2014 | 88 | 2014 |
| Base excision repair and its implications to cancer therapy GJ Grundy, JL Parsons Essays in biochemistry 64 (5), 831-843, 2020 | 81 | 2020 |
| PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2BGlu2 GJ Grundy, LM Polo, Z Zeng, SL Rulten, NC Hoch, P Paomephan, Y Xu, ... Nature communications 7 (1), 12404, 2016 | 81 | 2016 |
| Defective calcium binding to fibrillin-1: consequence of an N2144S change for fibrillin-1 structure and function S Kettle, X Yuan, G Grundy, V Knott, AK Downing, PA Handford Journal of molecular biology 285 (3), 1277-1287, 1999 | 81 | 1999 |
| The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins GJ Grundy, SL Rulten, R Arribas-Bosacoma, K Davidson, Z Kozik, ... Nature communications 7 (1), 11242, 2016 | 77 | 2016 |
| Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V (D) J recombination GJ Grundy, W Yang, M Gellert Proceedings of the National Academy of Sciences 107 (52), 22487-22492, 2010 | 65 | 2010 |
| Initial stages of V (D) J recombination: the organization of RAG1/2 and RSS DNA in the postcleavage complex GJ Grundy, S Ramón-Maiques, EK Dimitriadis, S Kotova, C Biertümpfel, ... Molecular cell 35 (2), 217-227, 2009 | 54 | 2009 |
| Non‐homologous end joining: common interaction sites and exchange of multiple factors in the DNA repair process SL Rulten, GJ Grundy Bioessays 39 (3), 1600209, 2017 | 51 | 2017 |
| Requirements for DNA hairpin formation by RAG1/2 GJ Grundy, JE Hesse, M Gellert Proceedings of the National Academy of Sciences 104 (9), 3078-3083, 2007 | 33 | 2007 |
| Effectiveness of PARP inhibition in enhancing the radiosensitivity of 3D spheroids of head and neck squamous cell carcinoma C Zhou, MR Fabbrizi, JR Hughes, GJ Grundy, JL Parsons Frontiers in Oncology 12, 940377, 2022 | 13 | 2022 |
| KH-like domains in PARP9/DTX3L and PARP14 coordinate protein–protein interactions to promote cancer cell survival H Saleh, T Liloglou, DJ Rigden, JL Parsons, GJ Grundy Journal of Molecular Biology 436 (4), 168434, 2024 | 7 | 2024 |
| An activation-induced cytidine deaminase-independent mechanism of secondary VH gene rearrangement in preimmune human B cells NS Longo, GJ Grundy, J Lee, M Gellert, PE Lipsky The Journal of Immunology 181 (11), 7825-7834, 2008 | 6 | 2008 |
| The role of autophagy in hypoxia-induced radioresistance RM Hill, M Fok, G Grundy, JL Parsons, S Rocha Radiotherapy and Oncology, 109951, 2023 | 3 | 2023 |
| Autophagy is the main driver of radioresistance of HNSCC cells in mild hypoxia RM Hill, C Li, JR Hughes, S Rocha, GJ Grundy, JL Parsons Journal of Cellular and Molecular Medicine 28 (12), e18482, 2024 | | 2024 |
| O239: Identification of novel radiosensitisers in colorectal cancer cells A Kler, M Fok, J Parsons, G Grundy, D Vimalachandran British Journal of Surgery 111 (Supplement_2), znae046. 023, 2024 | | 2024 |
