Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4) JM O'Donnell, HT Zhang Trends in pharmacological sciences 25 (3), 158-163, 2004 | 351 | 2004 |
Intruder-evoked aggression in isolated and nonisolated mice: Effects of psychomotor stimulants and l-Dopa KA Miczek, JM O'Donnell Psychopharmacology 57, 47-55, 1978 | 348 | 1978 |
Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling YF Li, YF Cheng, Y Huang, M Conti, SP Wilson, JM O'Donnell, HT Zhang Journal of Neuroscience 31 (1), 172-183, 2011 | 268 | 2011 |
Reversal of oxidative stress-induced anxiety by inhibition of phosphodiesterase-2 in mice A Masood, A Nadeem, SJ Mustafa, JM O'Donnell Journal of Pharmacology and Experimental Therapeutics 326 (2), 369-379, 2008 | 267 | 2008 |
Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme HT Zhang, Y Huang, SLC Jin, SA Frith, N Suvarna, M Conti, JM O'Donnell Neuropsychopharmacology 27 (4), 587-595, 2002 | 265 | 2002 |
Antidepressant-and anxiolytic-like effects of the phosphodiesterase-4 inhibitor rolipram on behavior depend on cyclic AMP response element binding protein-mediated neurogenesis … YF Li, Y Huang, SL Amsdell, L Xiao, JM O'donnell, HT Zhang Neuropsychopharmacology 34 (11), 2404-2419, 2009 | 217 | 2009 |
Inhibition of cyclic AMP phosphodiesterase (PDE4) reverses memory deficits associated with NMDA receptor antagonism HT Zhang, AM Crissman, NR Dorairaj, LJ Chandler, JM O'Donnell Neuropsychopharmacology 23 (2), 198-204, 2000 | 201 | 2000 |
Anxiogenic-like behavioral phenotype of mice deficient in phosphodiesterase 4B (PDE4B) HT Zhang, Y Huang, A Masood, LR Stolinski, Y Li, L Zhang, D Dlaboga, ... Neuropsychopharmacology 33 (7), 1611-1623, 2008 | 180 | 2008 |
Drug therapy of depression and anxiety disorders JM O'DONNELL Goodman & Gilman's the pharmacological basis of therapeutics, 397-415, 2011 | 178 | 2011 |
Effects of rolipram on scopolamine-induced impairment of working and reference memory in the radial-arm maze tests in rats HT Zhang, JM O'Donnell Psychopharmacology 150, 311-316, 2000 | 176 | 2000 |
Inhibition of the phosphodiesterase 4 (PDE4) enzyme reverses memory deficits produced by infusion of the MEK inhibitor U0126 into the CA1 subregion of the rat hippocampus HT Zhang, Y Zhao, Y Huang, NR Dorairaj, LJ Chandler, JM O'Donnell Neuropsychopharmacology 29 (8), 1432-1439, 2004 | 163 | 2004 |
Novel therapeutic targets in depression and anxiety: antioxidants as a candidate treatment Y Xu, C Wang, J J Klabnik, J M O'Donnell Current neuropharmacology 12 (2), 108-119, 2014 | 161 | 2014 |
Differential-reinforcement-of-low-rate 72-second schedule: selective effects of antidepressant drugs. JM O'Donnell, LS Seiden Journal of Pharmacology and Experimental Therapeutics 224 (1), 80-88, 1983 | 136 | 1983 |
Phosphodiesterases in the central nervous system: implications in mood and cognitive disorders Y Xu, HT Zhang, JM O’Donnell Phosphodiesterases as drug targets, 447-485, 2011 | 123 | 2011 |
Antidepressant-like effect of trans-resveratrol in chronic stress model: behavioral and neurochemical evidences Y Yu, R Wang, C Chen, X Du, L Ruan, J Sun, J Li, L Zhang, JM O'Donnell, ... Journal of psychiatric research 47 (3), 315-322, 2013 | 119 | 2013 |
Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus NU Suvarna, JM O'Donnell Journal of Pharmacology and Experimental Therapeutics 302 (1), 249-256, 2002 | 115 | 2002 |
Altered axonal targeting and short-term plasticity in the hippocampus of Disc1 mutant mice M Kvajo, H McKellar, LJ Drew, AM Lepagnol-Bestel, L Xiao, RJ Levy, ... Proceedings of the National Academy of Sciences 108 (49), E1349-E1358, 2011 | 112 | 2011 |
Effect of hemostatic risk factors on the individual probability of thrombosis during pregnancy and the puerperium A Gerhardt, RE Scharf, RB Zotz Thrombosis and haemostasis 90 (07), 77-85, 2003 | 111 | 2003 |
METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer’s disease through aberrant cell cycle events F Zhao, Y Xu, S Gao, L Qin, Q Austria, SL Siedlak, K Pajdzik, Q Dai, C He, ... Molecular neurodegeneration 16, 1-25, 2021 | 108 | 2021 |
Neuronal and inducible nitric oxide synthase expressions and activities in the hippocampi and cortices of young adult, aged cognitively unimpaired, and impaired Long–Evans rats A Law, J O’donnell, S Gauthier, R Quirion Neuroscience 112 (2), 267-275, 2002 | 107 | 2002 |