The future of antifungal drug therapy: novel compounds and targets C Mota Fernandes, D Dasilva, K Haranahalli, JB McCarthy, J Mallamo, ... Antimicrobial agents and chemotherapy 65 (2), 10.1128/aac. 01719-20, 2021 | 109 | 2021 |
Recent advances in the discovery and development of antibacterial agents targeting the cell-division protein FtsZ K Haranahalli, S Tong, I Ojima Bioorganic & medicinal chemistry 24 (24), 6354-6369, 2016 | 96 | 2016 |
Recent progress in the strategic incorporation of fluorine into medicinally active compounds K Haranahalli, T Honda, I Ojima Journal of fluorine chemistry 217, 29-40, 2019 | 73 | 2019 |
Acylhydrazones as antifungal agents targeting the synthesis of fungal sphingolipids C Lazzarini, K Haranahalli, R Rieger, HK Ananthula, PB Desai, ... Antimicrobial agents and chemotherapy 62 (5), 10.1128/aac. 00156-18, 2018 | 64 | 2018 |
SAR studies on aromatic acylhydrazone-based inhibitors of fungal sphingolipid synthesis as next-generation antifungal agents K Haranahalli, C Lazzarini, Y Sun, J Zambito, S Pathiranage, JB McCarthy, ... Journal of medicinal chemistry 62 (17), 8249-8273, 2019 | 25 | 2019 |
Identification of small molecule inhibitors of botulinum neurotoxin serotype E via footprint similarity Y Zhou, BE McGillick, YHG Teng, K Haranahalli, I Ojima, S Swaminathan, ... Bioorganic & medicinal chemistry 24 (20), 4875-4889, 2016 | 21 | 2016 |
Strategic incorporation of fluorine in the drug discovery of new-generation antitubercular agents targeting bacterial cell division protein FtsZ I Ojima, D Awasthi, L Wei, K Haranahalli Journal of fluorine chemistry 196, 44-56, 2017 | 18 | 2017 |
Antifungal Activity of Acylhydrazone Derivatives against Sporothrix spp JJ Artunduaga Bonilla, L Honorato, K Haranahalli, I Dib Ferreira Gremião, ... Antimicrobial Agents and Chemotherapy 65 (5), 10.1128/aac. 02593-20, 2021 | 15 | 2021 |
Preclinical evaluation of acylhydrazone SB-AF-1002 as a novel broad-spectrum antifungal agent C Lazzarini, K Haranahalli, JB McCarthy, J Mallamo, I Ojima, M Del Poeta Antimicrobial Agents and Chemotherapy 64 (9), 10.1128/aac. 00946-20, 2020 | 10 | 2020 |
Structure–activity relationship studies on 2, 5, 6-trisubstituted benzimidazoles targeting Mtb-FtsZ as antitubercular agents K Haranahalli, S Tong, S Kim, M Awwa, L Chen, SE Knudson, ... RSC Medicinal Chemistry 12 (1), 78-94, 2021 | 9 | 2021 |
Enhancing the visibility of women in the ACS division of medicinal chemistry (ACS MEDI) J Aldrich, S Allen, E Araujo, J Bronson, A Bryant-Friedrich, SK Cyr, ... ACS Medicinal Chemistry Letters 14 (4), 345-349, 2023 | 3 | 2023 |
Anti-fungals compounds targeting the synthesis of fungal sphingolipids I Ojima, M Del Poeta, C Lazzarini, K Haranahalli, Y Sun US Patent 11,414,378, 2022 | 3 | 2022 |
Engaging the medicinal chemists of tomorrow L Ferrins, E Araujo, MW Boudreau, MC Grenier-Davies, K Haranahalli, ... Journal of Medicinal Chemistry 65 (9), 6353-6355, 2022 | 3 | 2022 |
YMCC and YSN: An opportunity for scientific and cultural exchange L Ferrins, ME Olson, K Haranahalli, MC Grenier-Davies, MW Boudreau, ... Journal of medicinal chemistry 66 (17), 11591-11592, 2023 | 2 | 2023 |
SAR study of N′-(Salicylidene) heteroarenecarbohydrazides as promising antifungal agents Y Sun, S Kim, SY Shin, K Takemura, GS Matos, C Lazzarini, ... Bioorganic & Medicinal Chemistry 100, 117610, 2024 | 1 | 2024 |
Combination therapy of itraconazole and an acylhydrazone derivative (D13) for the treatment of sporotrichosis in cats I Dib Ferreira Gremião, GR Pereira-Oliveira, SA Pereira, ML Corrêa, ... Microbiology Spectrum 12 (6), e03967-23, 2024 | | 2024 |
Anti-fungals compounds targeting the synthesis of fungal sphingolipids I Ojima, M Del Poeta, C Lazzarini, K Hanarahalli, Y Sun US Patent 11,858,880, 2024 | | 2024 |
ANTI-FUNGALS-COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS I Ojima, K Haranahalli, M Del Poeta, A Garg WO Patent App. WO 2023/060161 A l, 2023 | | 2023 |
SAR Study of N’-(Salicylidene) Heteroarenecarbohydrazides as a New Class of Antifungal Agents Y Sun, S Kim, SY Shin, K Takemura, K Haranahalli, GS Matos, ... Available at SSRN 4502370, 2023 | | 2023 |
Methods of inhibiting fungal ceramide synthase for treatment of cryptococcus neoformans infection M Del Poeta, M Munshi, K Haranahalli, K You, I Ojima US Patent App. 16/495,605, 2020 | | 2020 |