Structural insights into RNA processing by the human RISC-loading complex HW Wang, C Noland, B Siridechadilok, DW Taylor, E Ma, K Felderer, ... Nature structural & molecular biology 16 (11), 1148-1153, 2009 | 326 | 2009 |
Dicer-TRBP complex formation ensures accurate mammalian microRNA biogenesis RC Wilson, A Tambe, MA Kidwell, CL Noland, CP Schneider, JA Doudna Molecular cell 57 (3), 397-407, 2015 | 302 | 2015 |
Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing HY Lee, K Zhou, AM Smith, CL Noland, JA Doudna Nucleic acids research 41 (13), 6568-6576, 2013 | 268 | 2013 |
Palmitoylation of TEAD transcription factors is required for their stability and function in Hippo pathway signaling CL Noland, S Gierke, PD Schnier, J Murray, WN Sandoval, M Sagolla, ... Structure 24 (1), 179-186, 2016 | 210 | 2016 |
siRNA repositioning for guide strand selection by human Dicer complexes CL Noland, E Ma, JA Doudna Molecular cell 43 (1), 110-121, 2011 | 182 | 2011 |
Multiple sensors ensure guide strand selection in human RNAi pathways CL Noland, JA Doudna Rna 19 (5), 639-648, 2013 | 155 | 2013 |
Substrate-specific structural rearrangements of human Dicer DW Taylor, E Ma, H Shigematsu, MA Cianfrocco, CL Noland, ... Nature structural & molecular biology 20 (6), 662-670, 2013 | 133 | 2013 |
Small molecule dysregulation of TEAD lipidation induces a dominant-negative inhibition of hippo pathway signaling JK Holden, JJ Crawford, CL Noland, S Schmidt, JR Zbieg, JA Lacap, ... Cell reports 31 (12), 2020 | 95 | 2020 |
Discovery of a potent and selective in vivo probe (GNE-272) for the bromodomains of CBP/EP300 TD Crawford, FA Romero, KW Lai, V Tsui, AM Taylor, G de Leon Boenig, ... Journal of medicinal chemistry 59 (23), 10549-10563, 2016 | 95 | 2016 |
Structure of the essential inner membrane lipopolysaccharide–PbgA complex T Clairfeuille, KR Buchholz, Q Li, E Verschueren, P Liu, D Sangaraju, ... Nature 584 (7821), 479-483, 2020 | 76 | 2020 |
Structural insights into lipoprotein N-acylation by Escherichia coli apolipoprotein N-acyltransferase CL Noland, MD Kattke, J Diao, SL Gloor, H Pantua, M Reichelt, ... Proceedings of the National Academy of Sciences 114 (30), E6044-E6053, 2017 | 57 | 2017 |
Structure of the human sodium leak channel NALCN M Kschonsak, HC Chua, CL Noland, C Weidling, T Clairfeuille, ... Nature 587 (7833), 313-318, 2020 | 47 | 2020 |
An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance TJ Hagenbeek, JR Zbieg, M Hafner, R Mroue, JA Lacap, NM Sodir, ... Nature Cancer 4 (6), 812-828, 2023 | 42 | 2023 |
Optimization of pan-Pim kinase activity and oral bioavailability leading to diaminopyrazole (GDC-0339) for the treatment of multiple myeloma X Wang, W Blackaby, V Allen, GKY Chan, JH Chang, PC Chiang, C Diène, ... Journal of Medicinal Chemistry 62 (4), 2140-2153, 2019 | 36 | 2019 |
Structural architecture of the human NALCN channelosome M Kschonsak, HC Chua, C Weidling, N Chakouri, CL Noland, K Schott, ... Nature 603 (7899), 180-186, 2022 | 27 | 2022 |
Developments in the implementation of acoustic droplet ejection for protein crystallography P Wu, C Noland, M Ultsch, B Edwards, D Harris, R Mayer, SF Harris Journal of Laboratory Automation 21 (1), 97-106, 2016 | 21 | 2016 |
Unstable mechanisms of resistance to inhibitors of Escherichia coli lipoprotein signal peptidase H Pantua, E Skippington, MG Braun, CL Noland, J Diao, Y Peng, SL Gloor, ... MBio 11 (5), 10.1128/mbio. 02018-20, 2020 | 18 | 2020 |
Inhibition of Escherichia coli lipoprotein diacylglyceryl transferase is insensitive to resistance caused by deletion of Braun’s lipoprotein J Diao, R Komura, T Sano, H Pantua, KM Storek, H Inaba, H Ogawa, ... Journal of Bacteriology 203 (13), 10.1128/jb. 00149-21, 2021 | 17 | 2021 |
Structure-guided unlocking of NaX reveals a non-selective tetrodotoxin-sensitive cation channel CL Noland, HC Chua, M Kschonsak, SA Heusser, N Braun, T Chang, ... Nature Communications 13 (1), 1416, 2022 | 16 | 2022 |
Reconstitution reveals two paths of force transmission through the kinetochore GE Hamilton, LA Helgeson, CL Noland, CL Asbury, YN Dimitrova, ... Elife 9, e56582, 2020 | 16 | 2020 |