Cells of the human intestinal tract mapped across space and time R Elmentaite, N Kumasaka, K Roberts, A Fleming, E Dann, HW King, ... Nature 597, 250–255, 2021 | 329 | 2021 |
Single-cell RNA-seq and computational analysis using temporal mixture modeling resolves TH1/TFH fate bifurcation in malaria T Lönnberg, V Svensson, KR James, D Fernandez-Ruiz, I Sebina, ... Science immunology 2 (9), eaal2192, 2017 | 283 | 2017 |
Distinct microbial and immune niches of the human colon KR James, T Gomes, R Elmentaite, N Kumar, EL Gulliver, HW King, ... Nature Immunology 21 (3), 343-353, 2020 | 217 | 2020 |
Single-cell sequencing of developing human gut reveals transcriptional links to childhood Crohn’s disease R Elmentaite, ADB Ross, K Roberts, KR James, D Ortmann, T Gomes, ... Developmental cell 55 (6), 771-783. e5, 2020 | 195 | 2020 |
High-resolution mRNA and secretome atlas of human enteroendocrine cells J Beumer, J Puschhof, J Bauzá-Martinez, A Martínez-Silgado, ... Cell 181 (6), 1291-1306. e19, 2020 | 147 | 2020 |
A roadmap for the human developmental cell atlas M Haniffa, D Taylor, S Linnarsson, BJ Aronow, GD Bader, RA Barker, ... Nature 597 (7875), 196-205, 2021 | 143 | 2021 |
Type I IFN signaling in CD8– DCs impairs Th1-dependent malaria immunity A Haque, SE Best, MM De Oca, KR James, A Ammerdorffer, CL Edwards, ... The Journal of clinical investigation 124 (6), 2483-2496, 2014 | 110 | 2014 |
Immunology in the era of single-cell technologies M Efremova, R Vento-Tormo, JE Park, SA Teichmann, KR James Annual Review of Immunology 38 (1), 727-757, 2020 | 72 | 2020 |
Single-cell analysis of CD4+ T-cell differentiation reveals three major cell states and progressive acceleration of proliferation V Proserpio, A Piccolo, L Haim-Vilmovsky, G Kar, T Lönnberg, ... Genome biology 17, 1-15, 2016 | 68 | 2016 |
IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection I Sebina, KR James, MSF Soon, LG Fogg, SE Best, F Labastida Rivera, ... PLoS Pathogens 12 (11), e1005999, 2016 | 63 | 2016 |
Malat1 suppresses immunity to infection through promoting expression of Maf and IL-10 in Th cells JP Hewitson, KA West, KR James, GF Rani, N Dey, A Romano, N Brown, ... The Journal of Immunology 204 (11), 2949-2960, 2020 | 62 | 2020 |
An integrated taxonomy for monogenic inflammatory bowel disease C Bolton, CS Smillie, S Pandey, R Elmentaite, G Wei, C Argmann, ... Gastroenterology 162 (3), 859-876, 2022 | 53 | 2022 |
IL‐6 promotes CD4+ T‐cell and B‐cell activation during Plasmodium infection I Sebina, LG Fogg, KR James, MSF Soon, J Akter, BS Thomas, GR Hill, ... Parasite immunology 39 (10), e12455, 2017 | 50 | 2017 |
Schistosoma japonicum eggs induce a proinflammatory, anti-fibrogenic phenotype in hepatic stellate cells BJ Anthony, KR James, GN Gobert, GA Ramm, DP McManus PloS one 8 (6), e68479, 2013 | 48 | 2013 |
Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory MSF Soon, HJ Lee, JA Engel, J Straube, BS Thomas, CPS Pernold, ... Nature Immunology 21 (12), 1597-1610, 2020 | 46 | 2020 |
Development of a novel CD4+ TCR transgenic line that reveals a dominant role for CD8+ dendritic cells and CD40 signaling in the generation of helper and CTL responses to blood … D Fernandez-Ruiz, LS Lau, N Ghazanfari, CM Jones, WY Ng, GM Davey, ... The Journal of Immunology 199 (12), 4165-4179, 2017 | 45 | 2017 |
Effect of Mature Blood-Stage Plasmodium Parasite Sequestration on Pathogen Biomass in Mathematical and In Vivo Models of Malaria DS Khoury, D Cromer, SE Best, KR James, PS Kim, CR Engwerda, ... Infection and immunity 82 (1), 212-220, 2014 | 42 | 2014 |
Immune cell dynamics unfolded by single-cell technologies DJ Kunz, T Gomes, KR James Frontiers in immunology 9, 1435, 2018 | 38 | 2018 |
IFN regulatory factor 3 balances Th1 and T follicular helper immunity during nonlethal blood-stage Plasmodium infection KR James, MSF Soon, I Sebina, D Fernandez-Ruiz, G Davey, UN Liligeto, ... The Journal of Immunology 200 (4), 1443-1456, 2018 | 36 | 2018 |
Host-mediated impairment of parasite maturation during blood-stage Plasmodium infection DS Khoury, D Cromer, J Akter, I Sebina, T Elliott, BS Thomas, MSF Soon, ... Proceedings of the National Academy of Sciences 114 (29), 7701-7706, 2017 | 32 | 2017 |