Soluble amyloid β-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration M Jin, N Shepardson, T Yang, G Chen, D Walsh, DJ Selkoe Proceedings of the National Academy of Sciences 108 (14), 5819-5824, 2011 | 1100 | 2011 |
Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors S Li, M Jin, T Koeglsperger, NE Shepardson, GM Shankar, DJ Selkoe Journal of Neuroscience 31 (18), 6627-6638, 2011 | 770 | 2011 |
Signalling and crosstalk of Rho GTPases in mediating axon guidance X Yuan, M Jin, X Xu, Y Song, C Wu, M Poo, S Duan Nature cell biology 5 (1), 38-45, 2003 | 396 | 2003 |
Semaphorin-3A guides radial migration of cortical neurons during development G Chen, J Sima, M Jin, K Wang, X Xue, W Zheng, Y Ding, X Yuan Nature neuroscience 11 (1), 36-44, 2008 | 261 | 2008 |
Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes S Hong, BL Ostaszewski, T Yang, TT O’Malley, M Jin, K Yanagisawa, S Li, ... Neuron 82 (2), 308-319, 2014 | 230 | 2014 |
Environmental novelty activates β2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aβ oligomers S Li, M Jin, D Zhang, T Yang, T Koeglsperger, H Fu, DJ Selkoe Neuron 77 (5), 929-941, 2013 | 205 | 2013 |
Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia H Fu, B Liu, JL Frost, S Hong, M Jin, B Ostaszewski, GM Shankar, ... Glia 60 (6), 993-1003, 2012 | 188 | 2012 |
C-terminally truncated forms of tau, but not full-length tau or its C-terminal fragments, are released from neurons independently of cell death D Kanmert, A Cantlon, CR Muratore, M Jin, TT O'Malley, G Lee, ... Journal of Neuroscience 35 (30), 10851-10865, 2015 | 171 | 2015 |
Long-range Ca2+ signaling from growth cone to soma mediates reversal of neuronal migration induced by slit-2 C Guan, H Xu, M Jin, X Yuan, M Poo Cell 129 (2), 385-395, 2007 | 166 | 2007 |
Ca2+-dependent regulation of rho GTPases triggers turning of nerve growth cones M Jin, C Guan, Y Jiang, G Chen, C Zhao, K Cui, Y Song, C Wu, M Poo, ... Journal of Neuroscience 25 (9), 2338-2347, 2005 | 159 | 2005 |
Diffusible, highly bioactive oligomers represent a critical minority of soluble Aβ in Alzheimer’s disease brain W Hong, Z Wang, W Liu, TT O’Malley, M Jin, M Willem, C Haass, ... Acta neuropathologica 136, 19-40, 2018 | 120 | 2018 |
Decoding the synaptic dysfunction of bioactive human AD brain soluble Aβ to inspire novel therapeutic avenues for Alzheimer’s disease S Li, M Jin, L Liu, Y Dang, BL Ostaszewski, DJ Selkoe Acta neuropathologica communications 6, 1-16, 2018 | 62 | 2018 |
An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer’s disease M Jin, B O’Nuallain, W Hong, J Boyd, VN Lagomarsino, TT O’Malley, ... Nature communications 9 (1), 2676, 2018 | 58 | 2018 |
Systematic analysis of time-dependent neural effects of soluble amyloid β oligomers in culture and in vivo: Prevention by scyllo-inositol M Jin, DJ Selkoe Neurobiology of disease 82, 152-163, 2015 | 54 | 2015 |
Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites JM Tokarew, DN El-Kodsi, NA Lengacher, TK Fehr, AP Nguyen, ... Acta neuropathologica 141, 725-754, 2021 | 40 | 2021 |
Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies JB Sanderson, S De, H Jiang, M Rovere, M Jin, L Zaccagnini, ... Brain communications 2 (1), fcaa010, 2020 | 25 | 2020 |
The familial British dementia mutation promotes formation of neurotoxic cystine cross-linked Amyloid Bri (ABri) oligomers A Cantlon, CS Frigerio, DB Freir, B Boland, M Jin, DM Walsh Journal of Biological Chemistry 290 (27), 16502-16516, 2015 | 16 | 2015 |
Learnings about Aβ from human brain recommend the use of a live-neuron bioassay for the discovery of next generation Alzheimer’s disease immunotherapeutics Z Wang, M Jin, W Hong, W Liu, D Reczek, VN Lagomarsino, Y Hu, ... Acta Neuropathologica Communications 11 (1), 39, 2023 | 5 | 2023 |
Oxidative modifications of parkin underlie its selective neuroprotection in adult human brain JM Tokarew, DN El-Kodsi, NA Lengacher, TK Fehr, AP Nguyen, ... bioRxiv, 2020.02. 19.953034, 2020 | 2 | 2020 |
Neutralizing anti-amyloid beta antibodies for the treatment of alzheimer's disease M Jin, L Pradier, D Reczek, D Selkoe, T Travaline, D Walsh US Patent App. 17/624,309, 2023 | | 2023 |