The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease M Wang, ND Beckmann, P Roussos, E Wang, X Zhou, Q Wang, C Ming, ... Scientific data 5 (1), 1-16, 2018 | 328 | 2018 |
The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease JY Hur, GR Frost, X Wu, C Crump, SJ Pan, E Wong, M Barros, T Li, P Nie, ... Nature 586 (7831), 735-740, 2020 | 274 | 2020 |
Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer’s disease M Wang, P Roussos, A McKenzie, X Zhou, Y Kajiwara, KJ Brennand, ... Genome medicine 8, 1-21, 2016 | 264 | 2016 |
Transformative network modeling of multi-omics data reveals detailed circuits, key regulators, and potential therapeutics for Alzheimer’s disease M Wang, A Li, M Sekiya, ND Beckmann, X Quan, N Schrode, ... Neuron 109 (2), 257-272. e14, 2021 | 123 | 2021 |
Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates M Lameijer, T Binderup, MMT Van Leent, ML Senders, F Fay, J Malkus, ... Nature biomedical engineering 2 (5), 279-292, 2018 | 115 | 2018 |
Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer’s disease AT McKenzie, S Moyon, M Wang, I Katsyv, WM Song, X Zhou, ... Molecular Neurodegeneration 12, 1-20, 2017 | 105 | 2017 |
Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex ZS Lorsch, PJ Hamilton, A Ramakrishnan, EM Parise, M Salery, ... Nature neuroscience 22 (9), 1413-1423, 2019 | 97 | 2019 |
The landscape of multiscale transcriptomic networks and key regulators in Parkinson’s disease Q Wang, Y Zhang, M Wang, WM Song, Q Shen, A McKenzie, I Choi, ... Nature communications 10 (1), 5234, 2019 | 96 | 2019 |
GO-function: deriving biologically relevant functions from statistically significant functions J Wang, X Zhou, J Zhu, Y Gu, W Zhao, J Zou, Z Guo Briefings in bioinformatics 13 (2), 216-227, 2012 | 85 | 2012 |
Revealing and avoiding bias in semantic similarity scores for protein pairs J Wang, X Zhou, J Zhu, C Zhou, Z Guo BMC bioinformatics 11, 1-11, 2010 | 53 | 2010 |
Prosaposin mediates inflammation in atherosclerosis MMT van Leent, TJ Beldman, YC Toner, MA Lameijer, N Rother, ... Science translational medicine 13 (584), eabe1433, 2021 | 52 | 2021 |
Integrated transcriptome and network analysis reveals spatiotemporal dynamics of calvarial suturogenesis G Holmes, AS Gonzalez-Reiche, N Lu, X Zhou, J Rivera, D Kriti, R Sebra, ... Cell Reports 32 (1), 2020 | 51 | 2020 |
Guidelines for bioinformatics of single-cell sequencing data analysis in Alzheimer’s disease: review, recommendation, implementation and application M Wang, W Song, C Ming, Q Wang, X Zhou, P Xu, A Krek, Y Yoon, L Ho, ... Molecular neurodegeneration 17 (1), 17, 2022 | 50 | 2022 |
Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity S Wahane, X Zhou, X Zhou, L Guo, MS Friedl, M Kluge, A Ramakrishnan, ... Science Advances 7 (9), eabd8811, 2021 | 43 | 2021 |
EPRS is a critical regulator of cell proliferation and estrogen signaling in ER+ breast cancer I Katsyv, M Wang, WM Song, X Zhou, Y Zhao, S Park, J Zhu, B Zhang, ... Oncotarget 7 (43), 69592, 2016 | 41 | 2016 |
Sex-specific transcriptional changes in response to adolescent social stress in the brain’s reward circuitry DM Walker, X Zhou, AM Cunningham, AP Lipschultz, A Ramakrishnan, ... Biological psychiatry 91 (1), 118-128, 2022 | 39 | 2022 |
EMUDRA: Ensemble of Multiple Drug Repositioning Approaches to improve prediction accuracy X Zhou, M Wang, I Katsyv, H Irie, B Zhang Bioinformatics 34 (18), 3151-3159, 2018 | 35 | 2018 |
Network models of primary melanoma microenvironments identify key melanoma regulators underlying prognosis WM Song, P Agrawal, R Von Itter, B Fontanals-Cirera, M Wang, X Zhou, ... Nature communications 12 (1), 1214, 2021 | 30 | 2021 |
Chromatin accessibility mapping of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder G Egervari, D Akpoyibo, T Rahman, JF Fullard, JE Callens, JA Landry, ... Nature communications 11 (1), 4634, 2020 | 27 | 2020 |
Sex specific molecular networks and key drivers of Alzheimer’s disease L Guo, J Cao, J Hou, Y Li, M Huang, L Zhu, L Zhang, Y Lee, ML Duarte, ... Molecular neurodegeneration 18 (1), 39, 2023 | 20 | 2023 |