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Xianxiao Zhou
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The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease
M Wang, ND Beckmann, P Roussos, E Wang, X Zhou, Q Wang, C Ming, ...
Scientific data 5 (1), 1-16, 2018
3282018
The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease
JY Hur, GR Frost, X Wu, C Crump, SJ Pan, E Wong, M Barros, T Li, P Nie, ...
Nature 586 (7831), 735-740, 2020
2742020
Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer’s disease
M Wang, P Roussos, A McKenzie, X Zhou, Y Kajiwara, KJ Brennand, ...
Genome medicine 8, 1-21, 2016
2642016
Transformative network modeling of multi-omics data reveals detailed circuits, key regulators, and potential therapeutics for Alzheimer’s disease
M Wang, A Li, M Sekiya, ND Beckmann, X Quan, N Schrode, ...
Neuron 109 (2), 257-272. e14, 2021
1232021
Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates
M Lameijer, T Binderup, MMT Van Leent, ML Senders, F Fay, J Malkus, ...
Nature biomedical engineering 2 (5), 279-292, 2018
1152018
Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer’s disease
AT McKenzie, S Moyon, M Wang, I Katsyv, WM Song, X Zhou, ...
Molecular Neurodegeneration 12, 1-20, 2017
1052017
Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex
ZS Lorsch, PJ Hamilton, A Ramakrishnan, EM Parise, M Salery, ...
Nature neuroscience 22 (9), 1413-1423, 2019
972019
The landscape of multiscale transcriptomic networks and key regulators in Parkinson’s disease
Q Wang, Y Zhang, M Wang, WM Song, Q Shen, A McKenzie, I Choi, ...
Nature communications 10 (1), 5234, 2019
962019
GO-function: deriving biologically relevant functions from statistically significant functions
J Wang, X Zhou, J Zhu, Y Gu, W Zhao, J Zou, Z Guo
Briefings in bioinformatics 13 (2), 216-227, 2012
852012
Revealing and avoiding bias in semantic similarity scores for protein pairs
J Wang, X Zhou, J Zhu, C Zhou, Z Guo
BMC bioinformatics 11, 1-11, 2010
532010
Prosaposin mediates inflammation in atherosclerosis
MMT van Leent, TJ Beldman, YC Toner, MA Lameijer, N Rother, ...
Science translational medicine 13 (584), eabe1433, 2021
522021
Integrated transcriptome and network analysis reveals spatiotemporal dynamics of calvarial suturogenesis
G Holmes, AS Gonzalez-Reiche, N Lu, X Zhou, J Rivera, D Kriti, R Sebra, ...
Cell Reports 32 (1), 2020
512020
Guidelines for bioinformatics of single-cell sequencing data analysis in Alzheimer’s disease: review, recommendation, implementation and application
M Wang, W Song, C Ming, Q Wang, X Zhou, P Xu, A Krek, Y Yoon, L Ho, ...
Molecular neurodegeneration 17 (1), 17, 2022
502022
Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity
S Wahane, X Zhou, X Zhou, L Guo, MS Friedl, M Kluge, A Ramakrishnan, ...
Science Advances 7 (9), eabd8811, 2021
432021
EPRS is a critical regulator of cell proliferation and estrogen signaling in ER+ breast cancer
I Katsyv, M Wang, WM Song, X Zhou, Y Zhao, S Park, J Zhu, B Zhang, ...
Oncotarget 7 (43), 69592, 2016
412016
Sex-specific transcriptional changes in response to adolescent social stress in the brain’s reward circuitry
DM Walker, X Zhou, AM Cunningham, AP Lipschultz, A Ramakrishnan, ...
Biological psychiatry 91 (1), 118-128, 2022
392022
EMUDRA: Ensemble of Multiple Drug Repositioning Approaches to improve prediction accuracy
X Zhou, M Wang, I Katsyv, H Irie, B Zhang
Bioinformatics 34 (18), 3151-3159, 2018
352018
Network models of primary melanoma microenvironments identify key melanoma regulators underlying prognosis
WM Song, P Agrawal, R Von Itter, B Fontanals-Cirera, M Wang, X Zhou, ...
Nature communications 12 (1), 1214, 2021
302021
Chromatin accessibility mapping of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder
G Egervari, D Akpoyibo, T Rahman, JF Fullard, JE Callens, JA Landry, ...
Nature communications 11 (1), 4634, 2020
272020
Sex specific molecular networks and key drivers of Alzheimer’s disease
L Guo, J Cao, J Hou, Y Li, M Huang, L Zhu, L Zhang, Y Lee, ML Duarte, ...
Molecular neurodegeneration 18 (1), 39, 2023
202023
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