Complex multi-enhancer contacts captured by genome architecture mapping RA Beagrie, A Scialdone, M Schueler, DCA Kraemer, M Chotalia, SQ Xie, ... Nature 543 (7646), 519-524, 2017 | 693 | 2017 |
Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs E Brookes, I de Santiago, D Hebenstreit, KJ Morris, T Carroll, SQ Xie, ... Cell stem cell 10 (2), 157-170, 2012 | 317 | 2012 |
Impact of artifact removal on ChIP quality metrics in ChIP-seq and ChIP-exo data TS Carroll, Z Liang, R Salama, R Stark, I de Santiago Frontiers in genetics 5, 75, 2014 | 239 | 2014 |
Master regulators of FGFR2 signalling and breast cancer risk MNC Fletcher, MAA Castro, X Wang, I De Santiago, M O’Reilly, SF Chin, ... Nature communications 4 (1), 2464, 2013 | 210 | 2013 |
Regulators of genetic risk of breast cancer identified by integrative network analysis MAA Castro, I de Santiago, TM Campbell, C Vaughn, TE Hickey, E Ross, ... Nature genetics 48 (1), 12-21, 2016 | 180 | 2016 |
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1 KB Meyer, M O’Reilly, K Michailidou, S Carlebur, SL Edwards, JD French, ... The American Journal of Human Genetics 93 (6), 1046-1060, 2013 | 142 | 2013 |
Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation M Ghoussaini, SL Edwards, K Michailidou, S Nord, R Cowper-Sal· lari, ... Nature communications 5 (1), 4999, 2014 | 134 | 2014 |
Combined image and genomic analysis of high-grade serous ovarian cancer reveals PTEN loss as a common driver event and prognostic classifier FC Martins, I Santiago, A Trinh, J Xian, A Guo, K Sayal, M Jimenez-Linan, ... Genome biology 15, 1-15, 2014 | 112 | 2014 |
Accumulated metabolites of hydroxybutyric acid serve as diagnostic and prognostic biomarkers of ovarian high-grade serous carcinomas M Hilvo, I De Santiago, P Gopalacharyulu, WD Schmitt, J Budczies, ... Cancer research 76 (4), 796-804, 2016 | 91 | 2016 |
Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells M Barbieri, SQ Xie, E Torlai Triglia, AM Chiariello, S Bianco, I de Santiago, ... Nature structural & molecular biology 24 (6), 515-524, 2017 | 87 | 2017 |
Eukaryotic gene regulation in three dimensions and its impact on genome evolution MM Babu, SC Janga, I de Santiago, A Pombo Current opinion in genetics & development 18 (6), 571-582, 2008 | 62 | 2008 |
FGFR2 risk SNPs confer breast cancer risk by augmenting oestrogen responsiveness TM Campbell, MAA Castro, I de Santiago, MNC Fletcher, S Halim, ... Carcinogenesis 37 (8), 741-750, 2016 | 55 | 2016 |
RNA polymerase II primes Polycomb‐repressed developmental genes throughout terminal neuronal differentiation C Ferrai, E Torlai Triglia, JR Risner‐Janiczek, T Rito, OJL Rackham, ... Molecular systems biology 13 (10), 946, 2017 | 48 | 2017 |
Master Regulators of Oncogenic KRAS Response in Pancreatic Cancer: An Integrative Network Biology Analysis S Sivakumar, I de Santiago, L Chlon, F Markowetz PLoS medicine 14 (1), e1002223, 2017 | 48 | 2017 |
Immunophenotypes of pancreatic ductal adenocarcinoma: Meta‐analysis of transcriptional subtypes I de Santiago, C Yau, L Heij, MR Middleton, F Markowetz, HI Grabsch, ... International journal of cancer 145 (4), 1125-1137, 2019 | 46 | 2019 |
BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes I de Santiago, W Liu, K Yuan, M O’Reilly, CSR Chilamakuri, BAJ Ponder, ... Genome biology 18, 1-17, 2017 | 34 | 2017 |
Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer FC Martins, DL Couturier, I De Santiago, CM Sauer, M Vias, M Angelova, ... Nature Communications 13 (1), 6360, 2022 | 18 | 2022 |
Analysis of ChIP-seq data in R/Bioconductor I de Santiago, T Carroll Chromatin Immunoprecipitation: Methods and Protocols, 195-226, 2018 | 12 | 2018 |
Data-Driven Medicine in the Diagnosis and Treatment of Infertility I De Santiago, L Polanski Journal of Clinical Medicine 11 (21), 6426, 2022 | 5 | 2022 |
Combination of mTOR inhibition and paclitaxel as a personalised strategy in the context of MYC-amplified high-grade serous ovarian cancer FC Martins, DL Couturier, I de Santiago, M Vias, D Sanders, A Piskorz, ... Annals of Oncology 30, vii10-vii11, 2019 | 4 | 2019 |