Genetics of human susceptibility to active and latent tuberculosis: present knowledge and future perspectives L Abel, J Fellay, DW Haas, E Schurr, G Srikrishna, M Urbanowski, ... The Lancet Infectious diseases 18 (3), e64-e75, 2018 | 151 | 2018 |
Cavitary tuberculosis: the gateway of disease transmission ME Urbanowski, AA Ordonez, CA Ruiz-Bedoya, SK Jain, WR Bishai The Lancet Infectious Diseases, 2020 | 133 | 2020 |
A systematic approach for developing bacteria-specific imaging tracers AA Ordonez, EA Weinstein, LE Bambarger, V Saini, YS Chang, ... Journal of Nuclear Medicine 58 (1), 144-150, 2017 | 108 | 2017 |
Dynamic imaging in patients with tuberculosis reveals heterogeneous drug exposures in pulmonary lesions AA Ordonez, H Wang, G Magombedze, CA Ruiz-Bedoya, S Srivastava, ... Nature medicine 26 (4), 529-534, 2020 | 103 | 2020 |
Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti–PD-1 in melanoma LS Cheung, J Fu, P Kumar, A Kumar, ME Urbanowski, EA Ihms, ... Proceedings of the National Academy of Sciences 116 (8), 3100-3105, 2019 | 62 | 2019 |
Pharmacokinetics of rifapentine and rifampin in a rabbit model of tuberculosis and correlation with clinical trial data D Rifat, B Prideaux, RM Savic, ME Urbanowski, TL Parsons, B Luna, ... Science translational medicine 10 (435), eaai7786, 2018 | 46 | 2018 |
Pathogenesis and animal models of post-primary (Bronchogenic) tuberculosis, a review RL Hunter, JK Actor, SA Hwang, A Khan, ME Urbanowski, D Kaushal, ... Pathogens 7 (1), 19, 2018 | 38 | 2018 |
Cathepsin K contributes to cavitation and collagen turnover in pulmonary tuberculosis A Kubler, C Larsson, B Luna, BB Andrade, EP Amaral, M Urbanowski, ... The Journal of infectious diseases 213 (4), 618-627, 2016 | 38 | 2016 |
Repetitive aerosol exposure promotes cavitary tuberculosis and enables screening for targeted inhibitors of extensive lung destruction ME Urbanowski, EA Ihms, K Bigelow, A Kübler, PT Elkington, WR Bishai The Journal of infectious diseases 218 (1), 53-63, 2018 | 33 | 2018 |
The integrated stress response mediates necrosis in murine Mycobacterium tuberculosis granulomas B Bhattacharya, S Xiao, S Chatterjee, ME Urbanowski, AA Ordonez, ... The Journal of Clinical Investigation, 2020 | 31 | 2020 |
Biomarkers for tuberculosis based on secreted, species-specific, bacterial small molecules SJ Pan, A Tapley, J Adamson, T Little, M Urbanowski, K Cohen, A Pym, ... The Journal of infectious diseases 212 (11), 1827-1834, 2015 | 30 | 2015 |
Matrix metalloproteinase inhibition in a murine model of cavitary tuberculosis paradoxically worsens pathology AA Ordonez, S Pokkali, J Sanchez-Bautista, MH Klunk, ME Urbanowski, ... The Journal of infectious diseases 219 (4), 633-636, 2019 | 29 | 2019 |
Diverse cavity types and evidence that mechanical action on the necrotic granuloma drives tuberculous cavitation EA Ihms, ME Urbanowski, WR Bishai The American journal of pathology 188 (7), 1666-1675, 2018 | 25 | 2018 |
Dual mTORC1/mTORC2 inhibition as a Host-Directed Therapeutic Target in Pathologically Distinct Mouse Models of Tuberculosis R Tasneen, DS Mortensen, PJ Converse, ME Urbanowski, A Upton, ... Antimicrobial agents and chemotherapy, AAC. 00253-21, 2021 | 10 | 2021 |
Assessing whether isoniazid is essential during the first 14 days of tuberculosis therapy: a phase 2a, open-label, randomised controlled trial A Diacon, S Miyahara, R Dawson, X Sun, E Hogg, K Donahue, ... The Lancet Microbe 1 (2), e84-e92, 2020 | 10 | 2020 |
Effective Host-Directed Therapy for Tuberculosis by Depletion of Myeloid-Derived Suppressor Cells and Related Cells Using a Diphtheria Toxin Fusion Protein S Parveen, S Lun, ME Urbanowski, M Cardin, J Shen, JR Murphy, ... The Journal of infectious diseases 224 (11), 1962-1972, 2021 | 5 | 2021 |
Effective host-directed therapy for tuberculosis by targeted depletion of myeloid-derived suppressor cells using a diphtheria toxin-based fusion protein S Parveen, S Lun, ME Urbanowski, M Cardin, JR Murphy, WR Bishai bioRxiv, 2020 | 2 | 2020 |
The integrated stress response mediates type I interferon driven necrosis in Mycobacterium tuberculosis granulomas B Bhattacharya, S Xiao, S Chatterjee, M Urbanowski, A Ordonez, EA Ihms, ... bioRxiv, 499467, 2018 | 2 | 2018 |
Penetration of rifampin and rifapentine into diseased lung in the rabbit cavity pulmonary disease model of TB D Rifat, M Urbanowski, B Luna, M Marzinke, V Dartois, R Savic, W Bishai, ... 8th International Workshop on Clinical Pharmacology of Tuberculosis Drugs, 2015 | 2 | 2015 |
Expanding Latent Tuberculosis Infection Testing and Treatment in Massachusetts Primary Care Clinics via the ECHO Model D Szkwarko, ME Urbanowski, R Thal, P Iyer, S Foley, LM Randall, ... Journal of primary care & community health 13, 21501319221119942, 2022 | 1 | 2022 |