In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia MC Skala, KM Riching, A Gendron-Fitzpatrick, J Eickhoff, KW Eliceiri, ... Proceedings of the National Academy of Sciences 104 (49), 19494-19499, 2007 | 1143 | 2007 |
Fluorescence lifetime imaging microscopy: fundamentals and advances in instrumentation, analysis, and applications R Datta, TM Heaster, JT Sharick, AA Gillette, MC Skala Journal of biomedical optics 25 (7), 071203-071203, 2020 | 569 | 2020 |
In vivo multiphoton fluorescence lifetime imaging<?xpp qa?> of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia MC Skala, KM Riching, DK Bird, A Gendron-Fitzpatrick, J Eickhoff, ... Journal of biomedical optics 12 (2), 024014-024014-10, 2007 | 409 | 2007 |
Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models ML Schulte, A Fu, P Zhao, J Li, L Geng, ST Smith, J Kondo, RJ Coffey, ... Nature medicine 24 (2), 194-202, 2018 | 372 | 2018 |
Optical metabolic imaging identifies glycolytic levels, subtypes, and early-treatment response in breast cancer AJ Walsh, RS Cook, HC Manning, DJ Hicks, A Lafontant, CL Arteaga, ... Cancer research 73 (20), 6164-6174, 2013 | 328 | 2013 |
Quantitative optical imaging of primary tumor organoid metabolism predicts drug response in breast cancer AJ Walsh, RS Cook, ME Sanders, L Aurisicchio, G Ciliberto, CL Arteaga, ... Cancer research 74 (18), 5184-5194, 2014 | 302 | 2014 |
Multiphoton microscopy of endogenous fluorescence differentiates normal, precancerous, and cancerous squamous epithelial tissues MC Skala, JM Squirrell, KM Vrotsos, JC Eickhoff, A Gendron-Fitzpatrick, ... Cancer research 65 (4), 1180-1186, 2005 | 294 | 2005 |
Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines EE Capowski, K Samimi, SJ Mayerl, MJ Phillips, I Pinilla, SE Howden, ... Development 146 (1), dev171686, 2019 | 283 | 2019 |
ROS-responsive microspheres for on demand antioxidant therapy in a model of diabetic peripheral arterial disease KM Poole, CE Nelson, RV Joshi, JR Martin, MK Gupta, SC Haws, ... Biomaterials 41, 166-175, 2015 | 205 | 2015 |
Photothermal optical coherence tomography of epidermal growth factor receptor in live cells using immunotargeted gold nanospheres MC Skala, MJ Crow, A Wax, JA Izatt Nano letters 8 (10), 3461-3467, 2008 | 195 | 2008 |
Patient-derived cancer organoid cultures to predict sensitivity to chemotherapy and radiation CA Pasch, PF Favreau, AE Yueh, CP Babiarz, AA Gillette, JT Sharick, ... Clinical Cancer Research 25 (17), 5376-5387, 2019 | 186 | 2019 |
Signal transducer and activator of transcription 3, mediated remodeling of the tumor microenvironment results in enhanced tumor drug delivery in a mouse model of pancreatic cancer NS Nagathihalli, JA Castellanos, C Shi, Y Beesetty, ML Reyzer, R Caprioli, ... Gastroenterology 149 (7), 1932-1943. e9, 2015 | 177 | 2015 |
Multiphoton redox ratio imaging for metabolic monitoring in vivo M Skala, N Ramanujam Advanced Protocols in Oxidative Stress II, 155-162, 2010 | 143 | 2010 |
Evaluating natural killer cell cytotoxicity against solid tumors using a microfluidic model JM Ayuso, R Truttschel, MM Gong, M Humayun, M Virumbrales-Munoz, ... Oncoimmunology 8 (3), 1553477, 2019 | 126 | 2019 |
Optical imaging of drug-induced metabolism changes in murine and human pancreatic cancer organoids reveals heterogeneous drug response AJ Walsh, JA Castellanos, NS Nagathihalli, NB Merchant, MC Skala Pancreas 45 (6), 863-869, 2016 | 126 | 2016 |
Classification of T-cell activation via autofluorescence lifetime imaging AJ Walsh, KP Mueller, K Tweed, I Jones, CM Walsh, NJ Piscopo, ... Nature biomedical engineering 5 (1), 77-88, 2021 | 125 | 2021 |
Derivation of adult canine intestinal organoids for translational research in gastroenterology L Chandra, DC Borcherding, D Kingsbury, T Atherly, YM Ambrosini, ... BMC biology 17, 1-21, 2019 | 122 | 2019 |
Protein-bound NAD (P) H lifetime is sensitive to multiple fates of glucose carbon JT Sharick, PF Favreau, AA Gillette, SM Sdao, MJ Merrins, MC Skala Scientific reports 8 (1), 5456, 2018 | 109 | 2018 |
In vivo photothermal optical coherence tomography of gold nanorod contrast agents JM Tucker-Schwartz, TA Meyer, CA Patil, CL Duvall, MC Skala Biomedical optics express 3 (11), 2881-2895, 2012 | 108 | 2012 |
Microfluidic tumor-on-a-chip model to evaluate the role of tumor environmental stress on NK cell exhaustion JM Ayuso, S Rehman, M Virumbrales-Munoz, PH McMinn, P Geiger, ... Science Advances 7 (8), eabc2331, 2021 | 107 | 2021 |