A synthetic antimicrobial peptidomimetic (LTX 109): stereochemical impact on membrane disruption J Isaksson, BO Brandsdal, M Engqvist, GE Flaten, JSM Svendsen, ... Journal of medicinal chemistry 54 (16), 5786-5795, 2011 | 185 | 2011 |
A combined atomic force microscopy and computational approach for the structural elucidation of breitfussin A and B: highly modified halogenated dipeptides from Thuiaria breitfussi KØ Hanssen, B Schuler, AJ Williams, TB Demissie, E Hansen, ... Angewandte Chemie 124 (49), 12404-12407, 2012 | 130 | 2012 |
Synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site II of human serum albumin A Sivertsen, J Isaksson, HKS Leiros, J Svenson, JS Svendsen, ... BMC Structural Biology 14, 1-14, 2014 | 120 | 2014 |
Single-stranded adenine-rich DNA and RNA retain structural characteristics of their respective double-stranded conformations and show directional differences in stacking pattern J Isaksson, S Acharya, J Barman, P Cheruku, J Chattopadhyaya Biochemistry 43 (51), 15996-16010, 2004 | 115 | 2004 |
Determination of absolute configuration and conformation of a cyclic dipeptide by NMR and chiral spectroscopic methods X Li, KH Hopmann, J Hudecova, J Isaksson, J Novotna, W Stensen, ... The Journal of Physical Chemistry A 117 (8), 1721-1736, 2013 | 69 | 2013 |
Beta-glucan-loaded nanofiber dressing improves wound healing in diabetic mice J Grip, RE Engstad, I Skjæveland, N Škalko-Basnet, J Isaksson, P Basnet, ... European Journal of Pharmaceutical Sciences 121, 269-280, 2018 | 68 | 2018 |
Cellular antioxidant effect of four bromophenols from the red algae, Vertebrata lanosa EK Olsen, E Hansen, J Isaksson, JH Andersen Marine Drugs 11 (8), 2769-2784, 2013 | 63 | 2013 |
Marine AChE inhibitors isolated from Geodia barretti: natural compounds and their synthetic analogs EK Olsen, E Hansen, LWK Moodie, J Isaksson, K Sepčić, M Cergolj, ... Organic & Biomolecular Chemistry 14 (5), 1629-1640, 2016 | 62 | 2016 |
A uniform mechanism correlating dangling-end stabilization and stacking geometry J Isaksson, J Chattopadhyaya Biochemistry 44 (14), 5390-5401, 2005 | 56 | 2005 |
An Electrochemical Probe of DNA Stacking in an Antisense Oligonucleotide Containing a C3′‐endo‐Locked Sugar EM Boon, JK Barton, PI Pradeepkumar, J Isaksson, C Petit, ... Angewandte Chemie 114 (18), 3552-3555, 2002 | 52 | 2002 |
Novel Antimicrobial Peptides EeCentrocins 1, 2 and EeStrongylocin 2 from the Edible Sea Urchin Echinus esculentus Have 6-Br-Trp Post-Translational Modifications RG Solstad, C Li, J Isaksson, J Johansen, J Svenson, K Stensvåg, T Haug PLoS One 11 (3), e0151820, 2016 | 46 | 2016 |
Probing the ATP-binding pocket of protein kinase DYRK1A with benzothiazole fragment molecules U Rothweiler, W Stensen, BO Brandsdal, J Isaksson, FA Leeson, ... Journal of medicinal chemistry 59 (21), 9814-9824, 2016 | 45 | 2016 |
Significant p K a Perturbation of Nucleobases Is an Intrinsic Property of the Sequence Context in DNA and RNA S Acharya, J Barman, P Cheruku, S Chatterjee, P Acharya, J Isaksson, ... Journal of the American Chemical Society 126 (28), 8674-8681, 2004 | 42 | 2004 |
Isolation and Characterization of Antimicrobial Peptides with Unusual Disulfide Connectivity from the Colonial Ascidian Synoicum turgens IKØ Hansen, J Isaksson, AG Poth, KØ Hansen, AJC Andersen, ... Marine drugs 18 (1), 51, 2020 | 39 | 2020 |
Characterization of Rhamnolipids Produced by an Arctic Marine Bacterium from the Pseudomonas fluorescence Group V Kristoffersen, T Rämä, J Isaksson, JH Andersen, WH Gerwick, ... Marine drugs 16 (5), 163, 2018 | 38 | 2018 |
Development of a biomimetic phospholipid vesicle-based permeation assay for the estimation of intestinal drug permeability E Naderkhani, J Isaksson, A Ryzhakov, GE Flaten Journal of Pharmaceutical Sciences 103 (6), 1882-1890, 2014 | 38 | 2014 |
Improved anticancer potency by head‐to‐tail cyclization of short cationic anticancer peptides containing a lipophilic β2,2‐amino acid V Tørfoss, J Isaksson, D Ausbacher, BO Brandsdal, GE Flaten, ... Journal of Peptide Science 18 (10), 609-619, 2012 | 38 | 2012 |
Securamine Derivatives from the Arctic Bryozoan Securiflustra securifrons KØ Hansen, J Isaksson, A Bayer, JA Johansen, JH Andersen, E Hansen Journal of natural products 80 (12), 3276-3283, 2017 | 36 | 2017 |
A focused fragment library targeting the antibiotic resistance enzyme-Oxacillinase-48: Synthesis, structural evaluation and inhibitor design S Akhter, BA Lund, A Ismael, M Langer, J Isaksson, T Christopeit, ... European journal of medicinal chemistry 145, 634-648, 2018 | 35 | 2018 |
Kinase chemodiversity from the Arctic: The breitfussins KØ Hansen, JH Andersen, A Bayer, SK Pandey, M Lorentzen, ... Journal of Medicinal Chemistry 62 (22), 10167-10181, 2019 | 33 | 2019 |