Involvement of phosphoinositide 3‐kinase in insulin‐or IGF‐1‐induced membrane ruffling. K Kotani, K Yonezawa, K Hara, H Ueda, Y Kitamura, H Sakaue, A Ando, ... The EMBO journal 13 (10), 2313-2321, 1994 | 431 | 1994 |
Synthesis and solution structure of the antimicrobial peptide protegrin‐1 A Aumelas, M Mangoni, C Roumestand, L Chiche, E Despaux, G Grassy, ... European Journal of Biochemistry 237 (3), 575-583, 1996 | 226 | 1996 |
Enhanced delivery of doxorubicin into the brain via a peptide-vector-mediated strategy: saturation kinetics and specificity C Rousselle, M Smirnova, P Clair, JM Lefauconnier, A Chavanieu, ... Journal of Pharmacology and Experimental Therapeutics 296 (1), 124-131, 2001 | 214 | 2001 |
The H-NS dimerization domain defines a new fold contributing to DNA recognition V Bloch, Y Yang, E Margeat, A Chavanieu, MT Augé, B Robert, S Arold, ... Nature Structural & Molecular Biology 10 (3), 212-218, 2003 | 180 | 2003 |
Change in membrane permeability induced by protegrin 1: implication of disulphide bridges for pore formation ME Mangoni, A Aumelas, P Charnet, C Roumestand, L Chiche, ... FEBS letters 383 (1-2), 93-98, 1996 | 157 | 1996 |
Solution structure and activity of the synthetic four-disulfide bond Mediterranean mussel defensin (MGD-1) YS Yang, G Mitta, A Chavanieu, B Calas, JF Sanchez, P Roch, A Aumelas Biochemistry 39 (47), 14436-14447, 2000 | 145 | 2000 |
Insulin-dependent formation of a complex containing an 85-kDa subunit of phosphatidylinositol 3-kinase and tyrosine-phosphorylated insulin receptor substrate 1. K Yonezawa, H Ueda, K Hara, K Nishida, A Ando, A Chavanieu, ... Journal of Biological Chemistry 267 (36), 25958-25965, 1992 | 132 | 1992 |
Structure-based discovery of an inhibitor of Arf activation by Sec7 domains through targeting of protein–protein complexes J Viaud, M Zeghouf, H Barelli, JC Zeeh, A Padilla, B Guibert, P Chardin, ... Proceedings of the National Academy of Sciences 104 (25), 10370-10375, 2007 | 120 | 2007 |
Oligomerization of protegrin-1 in the presence of DPC micelles. A proton high-resolution NMR study C Roumestand, V Louis, A Aumelas, G Grassy, B Calas, A Chavanieu FEBS letters 421 (3), 263-267, 1998 | 111 | 1998 |
Peptide compounds analogues of the glucagon-like peptide-1 (7-37) B Calas, G Grassy, A Chavanieu, CS de Menthiere, P Renard, B Pfeiffer, ... US Patent 6,620,910, 2003 | 98 | 2003 |
Uneven HAK/KUP/KT protein diversity among angiosperms: species distribution and perspectives M Nieves-Cordones, R Ródenas, A Chavanieu, RM Rivero, V Martinez, ... Frontiers in plant science 7, 127, 2016 | 85 | 2016 |
Structure-based design, synthesis, and biological evaluation of novel inhibitors of human cyclophilin A JF Guichou, J Viaud, C Mettling, G Subra, YL Lin, A Chavanieu Journal of medicinal chemistry 49 (3), 900-910, 2006 | 73 | 2006 |
Discovery of a highly active ligand of human pregnane X receptor: a case study from pharmacophore modeling and virtual screening to “in vivo” biological activity G Lemaire, C Benod, V Nahoum, A Pillon, AM Boussioux, JF Guichou, ... Molecular pharmacology 72 (3), 572-581, 2007 | 60 | 2007 |
Developments in SPR fragment screening A Chavanieu, M Pugnière Expert opinion on drug discovery 11 (5), 489-499, 2016 | 54 | 2016 |
Amino-acid changes acquired during evolution by olfactory receptor 912-93 modify the specificity of odorant recognition I Gaillard, S Rouquier, A Chavanieu, P Mollard, D Giorgi Human molecular genetics 13 (7), 771-780, 2004 | 54 | 2004 |
Suppression of breast cancer metastasis through the inactivation of ADP-ribosylation factor 1 X Xie, SC Tang, Y Cai, W Pi, L Deng, G Wu, A Chavanieu, Y Teng Oncotarget 7 (36), 58111, 2016 | 48 | 2016 |
Solution structure of the antimicrobial peptide ranalexin and a study of its interaction with perdeuterated dodecylphosphocholine micelles E Vignal, A Chavanieu, P Roch, L Chiche, G Grassy, B Calas, A Aumelas European journal of biochemistry 253 (1), 221-228, 1998 | 45 | 1998 |
Structural requirements of the N-terminal region of GLP-1-[7-37]-NH2 for receptor interaction and cAMP production C Sarrauste de Menthière, A Chavanieu, G Grassy, S Dalle, G Salazar, ... European journal of medicinal chemistry 39 (6), 473-480, 2004 | 42 | 2004 |
Distinct Amino Acids in the C-Linker Domain of the Arabidopsis K+ Channel KAT2 Determine Its Subcellular Localization and Activity at the Plasma Membrane M Nieves-Cordones, A Chavanieu, L Jeanguenin, C Alcon, W Szponarski, ... Plant physiology 164 (3), 1415-1429, 2014 | 41 | 2014 |
BIGH3 (TGFBI) Arg124 mutations influence the amyloid conversion of related peptides in vitro Implications in the BIGH3‐linked corneal dystrophies CF Schmitt‐Bernard, A Chavanieu, G Herrada, G Subra, B Arnaud, ... European journal of biochemistry 269 (21), 5149-5156, 2002 | 40 | 2002 |