Interplay of α-synuclein binding and conformational switching probed by single-molecule fluorescence ACM Ferreon, Y Gambin, EA Lemke, AA Deniz Proceedings of the National Academy of Sciences 106 (14), 5645-5650, 2009 | 449 | 2009 |
Mechanism of activation of protein kinase JAK2 by the growth hormone receptor AJ Brooks, W Dai, ML O’Mara, D Abankwa, Y Chhabra, RA Pelekanos, ... Science 344 (6185), 1249783, 2014 | 441 | 2014 |
Lateral mobility of proteins in liquid membranes revisited Y Gambin, R Lopez-Esparza, M Reffay, E Sierecki, NS Gov, M Genest, ... Proceedings of the National Academy of Sciences 103 (7), 2098-2102, 2006 | 431 | 2006 |
SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species M Moustaqil, E Ollivier, HP Chiu, S Van Tol, P Rudolffi-Soto, C Stevens, ... Emerging microbes & infections 10 (1), 178-195, 2021 | 208 | 2021 |
Structural basis of TIR-domain-assembly formation in MAL-and MyD88-dependent TLR4 signaling T Ve, PR Vajjhala, A Hedger, T Croll, F DiMaio, S Horsefield, X Yu, ... Nature structural & molecular biology 24 (9), 743-751, 2017 | 163 | 2017 |
Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae Y Gambin, N Ariotti, KA McMahon, M Bastiani, E Sierecki, O Kovtun, ... elife 3, e01434, 2014 | 151 | 2014 |
Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing Y Gambin, V VanDelinder, ACM Ferreon, EA Lemke, A Groisman, ... Nature methods 8 (3), 239-241, 2011 | 149 | 2011 |
Single-molecule fluorescence studies of intrinsically disordered proteins ACM Ferreon, CR Moran, Y Gambin, AA Deniz Methods in enzymology 472, 179-204, 2010 | 133 | 2010 |
Thinking outside the bug: molecular targets and strategies to overcome antibiotic resistance A Monserrat-Martinez, Y Gambin, E Sierecki International journal of molecular sciences 20 (6), 1255, 2019 | 103 | 2019 |
Multicolor single-molecule FRET to explore protein folding and binding Y Gambin, AA Deniz Molecular BioSystems 6 (9), 1540-1547, 2010 | 98 | 2010 |
Direct single-molecule observation of a protein living in two opposed native structures Y Gambin, A Schug, EA Lemke, JJ Lavinder, ACM Ferreon, TJ Magliery, ... Proceedings of the National Academy of Sciences 106 (25), 10153-10158, 2009 | 97 | 2009 |
Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential B Meyer, J Chiaravalli, S Gellenoncourt, P Brownridge, DP Bryne, LA Daly, ... Nature Communications 12 (1), 5553, 2021 | 90 | 2021 |
Ultrafast microfluidic mixer with three-dimensional flow focusing for studies of biochemical kinetics Y Gambin, C Simonnet, V VanDelinder, A Deniz, A Groisman Lab on a Chip 10 (5), 598-609, 2010 | 88 | 2010 |
Viral M45 and necroptosis‐associated proteins form heteromeric amyloid assemblies CLL Pham, N Shanmugam, M Strange, A O'Carroll, JWP Brown, ... EMBO reports 20 (2), e46518, 2019 | 85 | 2019 |
Structure of a PSI–LHCI–cyt b6f supercomplex in Chlamydomonas reinhardtii promoting cyclic electron flow under anaerobic conditions J Steinbeck, IL Ross, R Rothnagel, P Gäbelein, S Schulze, N Giles, R Ali, ... Proceedings of the National Academy of Sciences 115 (41), 10517-10522, 2018 | 76 | 2018 |
Microfluidic device for single-molecule experiments with enhanced photostability EA Lemke, Y Gambin, V Vandelinder, EM Brustad, HW Liu, PG Schultz, ... Journal of the American Chemical Society 131 (38), 13610-13612, 2009 | 76 | 2009 |
Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation YJ Chai, E Sierecki, VM Tomatis, RS Gormal, N Giles, IC Morrow, D Xia, ... Journal of Cell Biology 214 (6), 705-718, 2016 | 74 | 2016 |
MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography MTB Clabbers, S Holmes, TW Muusse, PR Vajjhala, SJ Thygesen, ... Nature communications 12 (1), 2578, 2021 | 73 | 2021 |
Counteracting chemical chaperone effects on the single-molecule α-synuclein structural landscape ACM Ferreon, MM Moosa, Y Gambin, AA Deniz Proceedings of the National Academy of Sciences 109 (44), 17826-17831, 2012 | 71 | 2012 |
Cortactin Scaffolds Arp2/3 and WAVE2 at the Epithelial Zonula Adherens*♦ SP Han, Y Gambin, GA Gomez, S Verma, N Giles, M Michael, SK Wu, ... Journal of Biological Chemistry 289 (11), 7764-7775, 2014 | 70 | 2014 |