LncRNA Dum interacts with Dnmts to regulate Dppa2 expression during myogenic differentiation and muscle regeneration L Wang, Y Zhao, X Bao, X Zhu, YK Kwok, K Sun, X Chen, Y Huang, ... Cell research 25 (3), 335-350, 2015 | 256 | 2015 |
Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm I Aksoy, R Jauch, J Chen, M Dyla, U Divakar, GK Bogu, R Teo, ... The EMBO journal 32 (7), 938-953, 2013 | 212 | 2013 |
Capturing the interactome of newly transcribed RNA X Bao, X Guo, M Yin, M Tariq, Y Lai, S Kanwal, J Zhou, N Li, Y Lv, ... Nature methods 15 (3), 213-220, 2018 | 193 | 2018 |
Linc-YY1 promotes myogenic differentiation and muscle regeneration through an interaction with the transcription factor YY1 L Zhou, K Sun, YU Zhao, S Zhang, X Wang, Y Li, L Lu, X Chen, F Chen, ... Nature communications 6 (1), 10026, 2015 | 184 | 2015 |
Assessment of CASP7 structure predictions for template free targets R Jauch, HC Yeo, PR Kolatkar, ND Clarke Proteins: Structure, Function, and Bioinformatics 69 (S8), 57-67, 2007 | 165 | 2007 |
A unique Oct4 interface is crucial for reprogramming to pluripotency D Esch, J Vahokoski, MR Groves, V Pogenberg, V Cojocaru, ... Nature cell biology 15 (3), 295-301, 2013 | 161 | 2013 |
Human accelerated region 1 noncoding RNA is repressed by REST in Huntington's disease R Johnson, N Richter, R Jauch, PM Gaughwin, C Zuccato, E Cattaneo, ... Physiological genomics 41 (3), 269-274, 2010 | 135 | 2010 |
Molecular basis for the genome engagement by Sox proteins L Hou, Y Srivastava, R Jauch Seminars in cell & developmental biology 63, 2-12, 2017 | 132 | 2017 |
Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells I Aksoy, V Giudice, E Delahaye, F Wianny, M Aubry, M Mure, J Chen, ... Nature communications 5 (1), 3719, 2014 | 129 | 2014 |
Conversion of Sox17 into a pluripotency reprogramming factor by reengineering its association with Oct4 on DNA R Jauch, I Aksoy, AP Hutchins, CKL Ng, XF Tian, J Chen, P Palasingam, ... Stem cells 29 (6), 940-951, 2011 | 113 | 2011 |
Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog R Jauch, CKL Ng, KS Saikatendu, RC Stevens, PR Kolatkar Journal of molecular biology 376 (3), 758-770, 2008 | 109 | 2008 |
Deciphering the Sox-Oct partner code by quantitative cooperativity measurements CKL Ng, NX Li, S Chee, S Prabhakar, PR Kolatkar, R Jauch Nucleic acids research 40 (11), 4933-4941, 2012 | 101 | 2012 |
Mitogenactivated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment R Jauch, MK Cho, S Jäkel, C Netter, K Schreiter, B Aicher, M Zweckstetter, ... The EMBO journal 25 (17), 4020-4032, 2006 | 99 | 2006 |
The structure of Sox17 bound to DNA reveals a conserved bending topology but selective protein interaction platforms P Palasingam, R Jauch, CKL Ng, PR Kolatkar Journal of molecular biology 388 (3), 619-630, 2009 | 98 | 2009 |
Distinct transcriptional regulatory modules underlie STAT3’s cell type-independent and cell type-specific functions AP Hutchins, D Diez, Y Takahashi, S Ahmad, R Jauch, ML Tremblay, ... Nucleic acids research 41 (4), 2155-2170, 2013 | 96 | 2013 |
SOXE transcription factors form selective dimers on non-compact DNA motifs through multifaceted interactions between dimerization and high-mobility group domains YH Huang, A Jankowski, KSE Cheah, S Prabhakar, R Jauch Scientific reports 5 (1), 10398, 2015 | 87 | 2015 |
Crystal structure of the Sox4 HMG/DNA complex suggests a mechanism for the positional interdependence in DNA recognition R Jauch, CKL Ng, K Narasimhan, PR Kolatkar The Biochemical journal 443 (1), 39-47, 2012 | 86 | 2012 |
Dissecting the role of distinct OCT4-SOX2 heterodimer configurations in pluripotency N Tapia, C MacCarthy, D Esch, A Gabriele Marthaler, U Tiemann, ... Scientific reports 5 (1), 13533, 2015 | 84 | 2015 |
Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies MF Portnoi, MC Dumargne, S Rojo, SF Witchel, AJ Duncan, C Eozenou, ... Human molecular genetics 27 (7), 1228-1240, 2018 | 82 | 2018 |
FOXA1 mutations reveal distinct chromatin profiles and influence therapeutic response in breast cancer A Arruabarrena-Aristorena, JLV Maag, S Kittane, Y Cai, WR Karthaus, ... Cancer cell 38 (4), 534-550. e9, 2020 | 80 | 2020 |