| Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-222, 2016 | 13356* | 2016 |
| Lassa virus entry requires a trigger-induced receptor switch LT Jae, M Raaben, AS Herbert, AI Kuehne, AS Wirchnianski, TK Soh, ... Science 344 (6191), 1506-1510, 2014 | 295 | 2014 |
| Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy K Bartsch, K Knittler, C Borowski, S Rudnik, M Damme, K Aden, ... Human molecular genetics 26 (20), 3960-3972, 2017 | 209 | 2017 |
| Common pathobiochemical hallmarks of progranulin-associated frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis JK Götzl, K Mori, M Damme, K Fellerer, S Tahirovic, G Kleinberger, ... Acta neuropathologica 127 (6), 845-860, 2014 | 204 | 2014 |
| In vivo evidence for lysosome depletion and impaired autophagic clearance in hereditary spastic paraplegia type SPG11 RE Varga, M Khundadze, M Damme, S Nietzsche, B Hoffmann, T Stauber, ... PLoS genetics 11 (8), e1005454, 2015 | 132 | 2015 |
| Progranulin functions as a cathepsin D chaperone to stimulate axonal outgrowth in vivo S Beel, M Moisse, M Damme, L De Muynck, W Robberecht, ... Human molecular genetics 26 (15), 2850-2863, 2017 | 126 | 2017 |
| Autophagy in neuronal cells: general principles and physiological and pathological functions M Damme, T Suntio, P Saftig, EL Eskelinen Acta neuropathologica 129 (3), 337-362, 2015 | 114 | 2015 |
| Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome R De Pace, M Skirzewski, M Damme, R Mattera, J Mercurio, AM Foster, ... PLoS genetics 14 (4), e1007363, 2018 | 101 | 2018 |
| PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing AL Gavin, D Huang, C Huber, A Mårtensson, V Tardif, PD Skog, TR Blane, ... Nature immunology 19 (9), 942-953, 2018 | 97 | 2018 |
| Arylsulfatase G inactivation causes loss of heparan sulfate 3-O-sulfatase activity and mucopolysaccharidosis in mice B Kowalewski, WC Lamanna, R Lawrence, M Damme, S Stroobants, ... Proceedings of the National Academy of Sciences 109 (26), 10310-10315, 2012 | 95 | 2012 |
| Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis ARA Marques, A Di Spiezio, N Thießen, L Schmidt, J Grötzinger, ... Autophagy 16 (5), 811-825, 2020 | 94 | 2020 |
| Lysosomal dysfunction causes neurodegeneration in mucolipidosis II ‘knock-in’mice K Kollmann, M Damme, S Markmann, W Morelle, M Schweizer, ... Brain 135 (9), 2661-2675, 2012 | 91 | 2012 |
| Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease P Lüningschrör, B Binotti, B Dombert, P Heimann, A Perez-Lara, C Slotta, ... Nature communications 8 (1), 678, 2017 | 72 | 2017 |
| Mannose 6-dephosphorylation of lysosomal proteins mediated by acid phosphatases Acp2 and Acp5 G Makrypidi, M Damme, S Müller-Loennies, M Trusch, B Schmidt, ... Molecular and cellular biology, MCB. 06195-11, 2011 | 62 | 2011 |
| A homozygous founder missense variant in arylsulfatase G abolishes its enzymatic activity causing atypical Usher syndrome in humans S Khateb, B Kowalewski, N Bedoni, M Damme, N Pollack, A Saada, ... Genetics in Medicine, 2018 | 58 | 2018 |
| Gene disruption of Mfsd8 in mice provides the first animal model for CLN7 disease M Damme, L Brandenstein, S Fehr, W Jankowiak, U Bartsch, M Schweizer, ... Neurobiology of disease 65, 12-24, 2014 | 58 | 2014 |
| The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons P Lüningschrör, G Werner, S Stroobants, S Kakuta, B Dombert, D Sinske, ... Cell Reports 30 (10), 3506-3519. e6, 2020 | 49 | 2020 |
| Loss of TMEM 106B potentiates lysosomal and FTLD‐like pathology in progranulin‐deficient mice G Werner, M Damme, M Schludi, J Gnörich, K Wind, K Fellerer, B Wefers, ... EMBO reports 21 (10), e50241, 2020 | 42 | 2020 |
| Ubiquitin C-terminal hydrolase L1 (UCH-L1) loss causes neurodegeneration by altering protein turnover in the first postnatal weeks AT Reinicke, K Laban, M Sachs, V Kraus, M Walden, M Damme, W Sachs, ... Proceedings of the National Academy of Sciences 116 (16), 7963-7972, 2019 | 42 | 2019 |
| Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L LRT Savalas, B Gasnier, M Damme, T Lübke, C Wrocklage, C Debacker, ... Biochemical Journal 439 (1), 113-128, 2011 | 40 | 2011 |
