Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase Y Buganim, DA Faddah, AW Cheng, E Itskovich, S Markoulaki, K Ganz, ... Cell 150 (6), 1209-1222, 2012 | 968 | 2012 |
Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling G Sahay, W Querbes, C Alabi, A Eltoukhy, S Sarkar, C Zurenko, ... Nature biotechnology 31 (7), 653-658, 2013 | 841 | 2013 |
Mechanisms and models of somatic cell reprogramming Y Buganim, DA Faddah, R Jaenisch Nature Reviews Genetics 14 (6), 427-439, 2013 | 542 | 2013 |
Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells BW Carey, S Markoulaki, JH Hanna, DA Faddah, Y Buganim, J Kim, ... Cell stem cell 9 (6), 588-598, 2011 | 401 | 2011 |
Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease S Sarkar, B Carroll, Y Buganim, D Maetzel, AHM Ng, JP Cassady, ... Cell reports 5 (5), 1302-1315, 2013 | 319 | 2013 |
Direct reprogramming of fibroblasts into embryonic Sertoli-like cells by defined factors Y Buganim, E Itskovich, YC Hu, AW Cheng, K Ganz, S Sarkar, D Fu, ... Cell stem cell 11 (3), 373-386, 2012 | 202 | 2012 |
p53‐repressed miRNAs are involved with E2F in a feed‐forward loop promoting proliferation R Brosh, R Shalgi, A Liran, G Landan, K Korotayev, GH Nguyen, E Enerly, ... Molecular systems biology 4 (1), 229, 2008 | 185 | 2008 |
The developmental potential of iPSCs is greatly influenced by reprogramming factor selection Y Buganim, S Markoulaki, N Van Wietmarschen, H Hoke, T Wu, K Ganz, ... Cell stem cell 15 (3), 295-309, 2014 | 180 | 2014 |
Mutant p53R175H upregulates Twist1 expression and promotes epithelial–mesenchymal transition in immortalized prostate cells I Kogan-Sakin, Y Tabach, Y Buganim, A Molchadsky, H Solomon, ... Cell Death & Differentiation 18 (2), 271-281, 2011 | 180 | 2011 |
Single-cell analysis reveals that expression of nanog is biallelic and equally variable as that of other pluripotency factors in mouse ESCs DA Faddah, H Wang, AW Cheng, Y Katz, Y Buganim, R Jaenisch Cell stem cell 13 (1), 23-29, 2013 | 127 | 2013 |
Mutant p53R273H attenuates the expression of phase 2 detoxifying enzymes and promotes the survival of cells with high levels of reactive oxygen species E Kalo, I Kogan-Sakin, H Solomon, E Bar-Nathan, M Shay, Y Shetzer, ... Journal of cell science 125 (22), 5578-5586, 2012 | 126 | 2012 |
p53 is required for brown adipogenic differentiation and has a protective role against diet-induced obesity A Molchadsky, O Ezra, PG Amendola, D Krantz, I Kogan-Sakin, ... Cell Death & Differentiation 20 (5), 774-783, 2013 | 124 | 2013 |
Modulated expression of WFDC1 during carcinogenesis and cellular senescence S Madar, R Brosh, Y Buganim, O Ezra, I Goldstein, H Solomon, I Kogan, ... Carcinogenesis 30 (1), 20-27, 2009 | 105 | 2009 |
Amplification of the 20q chromosomal arm occurs early in tumorigenic transformation and may initiate cancer Y Tabach, I Kogan-Sakin, Y Buganim, H Solomon, N Goldfinger, ... PloS one 6 (1), e14632, 2011 | 103 | 2011 |
Various p53 mutant proteins differently regulate the Ras circuit to induce a cancer-related gene signature H Solomon, Y Buganim, I Kogan-Sakin, L Pomeraniec, Y Assia, S Madar, ... Journal of cell science 125 (13), 3144-3152, 2012 | 101 | 2012 |
Mutant p53 attenuates the SMAD-dependent transforming growth factor β1 (TGF-β1) signaling pathway by repressing the expression of TGF-β receptor type II E Kalo, Y Buganim, KE Shapira, H Besserglick, N Goldfinger, L Weisz, ... Molecular and cellular biology 27 (23), 8228-8242, 2007 | 100 | 2007 |
p53 Regulates the Ras circuit to inhibit the expression of a cancer-related gene signature by various molecular pathways Y Buganim, H Solomon, Y Rais, D Kistner, I Nachmany, M Brait, S Madar, ... Cancer research 70 (6), 2274-2284, 2010 | 92 | 2010 |
Prostate stromal cells produce CXCL-1, CXCL-2, CXCL-3 and IL-8 in response to epithelia-secreted IL-1 I Kogan-Sakin, M Cohen, N Paland, S Madar, H Solomon, A Molchadsky, ... Carcinogenesis 30 (4), 698-705, 2009 | 91 | 2009 |
Wide-scale analysis of human functional transcription factor binding reveals a strong bias towards the transcription start site Y Tabach, R Brosh, Y Buganim, A Reiner, O Zuk, A Yitzhaky, M Koudritsky, ... PloS one 2 (8), e807, 2007 | 88 | 2007 |
Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect M Milyavsky, I Shats, A Cholostoy, R Brosh, Y Buganim, L Weisz, I Kogan, ... Cancer Cell 11 (2), 133-146, 2007 | 84 | 2007 |