Hachimoji DNA and RNA: A genetic system with eight building blocks S Hoshika, NA Leal, MJ Kim, MS Kim, NB Karalkar, HJ Kim, AM Bates, ... Science 363 (6429), 884-887, 2019 | 453 | 2019 |
Escherichia coli “Marionette” strains with 12 highly optimized small-molecule sensors AJ Meyer, TH Segall-Shapiro, E Glassey, J Zhang, CA Voigt Nature chemical biology 15 (2), 196-204, 2019 | 441 | 2019 |
A ‘resource allocator’for transcription based on a highly fragmented T7 RNA polymerase TH Segall‐Shapiro, AJ Meyer, AD Ellington, ED Sontag, CA Voigt Molecular systems biology 10 (7), 742, 2014 | 198 | 2014 |
Directed evolution of genetic parts and circuits by compartmentalized partnered replication JW Ellefson, AJ Meyer, RA Hughes, JR Cannon, JS Brodbelt, ... Nature biotechnology 32 (1), 97-101, 2014 | 185 | 2014 |
Directed Evolution of a Panel of Orthogonal T7 RNA Polymerase Variants for in Vivo or in Vitro Synthetic Circuitry AJ Meyer, JW Ellefson, AD Ellington ACS synthetic biology 4 (10), 1070-1076, 2015 | 135 | 2015 |
Transcription yield of fully 2′-modified RNA can be increased by the addition of thermostabilizing mutations to T7 RNA polymerase mutants AJ Meyer, DJ Garry, B Hall, MM Byrom, HG McDonald, X Yang, YW Yin, ... Nucleic acids research 43 (15), 7480-7488, 2015 | 76 | 2015 |
Abiotic self-replication AJ Meyer, JW Ellefson, AD Ellington Accounts of Chemical Research 45 (12), 2097-2105, 2012 | 44 | 2012 |
Downregulation of protein 4.1 R, a mature centriole protein, disrupts centrosomes, alters cell cycle progression, and perturbs mitotic spindles and anaphase SW Krauss, JR Spence, S Bahmanyar, AIM Barth, MM Go, D Czerwinski, ... Molecular and cellular biology 28 (7), 2283-2294, 2008 | 42 | 2008 |
Structural protein 4.1 R is integrally involved in nuclear envelope protein localization, centrosome–nucleus association and transcriptional signaling AJ Meyer, DK Almendrala, MM Go, SW Krauss Journal of Cell Science 124 (9), 1433-1444, 2011 | 37 | 2011 |
In vitro selection using modified or unnatural nucleotides GM Stovall, RS Bedenbaugh, S Singh, AJ Meyer, PJ Hatala, AD Ellington, ... Current Protocols in Nucleic Acid Chemistry 56 (1), 9.6. 1-9.6. 33, 2014 | 36 | 2014 |
Library generation by gene shuffling AJ Meyer, JW Ellefson, AD Ellington Current protocols in molecular biology 105 (1), 15.12. 1-15.12. 7, 2014 | 32 | 2014 |
Genetic alphabet expansion transcription generating functional RNA molecules containing a five-letter alphabet including modified unnatural and natural base nucleotides by … M Kimoto, AJ Meyer, I Hirao, AD Ellington Chemical Communications 53 (91), 12309-12312, 2017 | 27 | 2017 |
Organism engineering for the bioproduction of the triaminotrinitrobenzene (TATB) precursor phloroglucinol (PG) A Meyer, I Saaem, A Silverman, VA Varaljay, R Mickol, S Blum, AV Tobias, ... ACS synthetic biology 8 (12), 2746-2755, 2019 | 26 | 2019 |
In Vitro Selection for Small-Molecule-Triggered Strand Displacement and Riboswitch Activity L Martini, AJ Meyer, JW Ellefson, JN Milligan, M Forlin, AD Ellington, ... ACS Synthetic Biology 4 (10), 1144-1150, 2015 | 23 | 2015 |
An in vitro Autogene EA Davidson, AJ Meyer, JW Ellefson, M Levy, AD Ellington ACS synthetic biology 1 (5), 190-196, 2012 | 23 | 2012 |
Genetically modifying skin microbe to produce violacein and augmenting microbiome did not defend Panamanian golden frogs from disease MH Becker, JAN Brophy, K Barrett, E Bronikowski, M Evans, E Glassey, ... ISME communications 1 (1), 57, 2021 | 22 | 2021 |
Marionette: E. coli containing 12 highly-optimized small molecule sensors AJ Meyer, TH Segall-Shapiro, CA Voigt BioRxiv, 285866, 2018 | 11 | 2018 |
Characterizing chemical signaling between engineered “microbial sentinels” in porous microplates CA Vaiana, H Kim, J Cottet, K Oai, Z Ge, K Conforti, AM King, AJ Meyer, ... Molecular Systems Biology 18 (3), e10785, 2022 | 10 | 2022 |
Molecular evolution picks up the PACE AJ Meyer, AD Ellington Nature biotechnology 29 (6), 502-503, 2011 | 4 | 2011 |
Predicting evolution of the transcription regulatory network in a bacteriophage DJ Garry, AJ Meyer, JW Ellefson, JJ Bull, AD Ellington Genome biology and evolution 10 (10), 2614-2628, 2018 | | 2018 |