Overexpression of vascular endothelial growth factor (VEGF) in the retinal pigment epithelium leads to the development of choroidal neovascularization K Spilsbury, KL Garrett, WY Shen, IJ Constable, PE Rakoczy The American journal of pathology 157 (1), 135-144, 2000 | 514 | 2000 |
Lipofuscin of the retinal pigment epithelium: a review CJ Kennedy, PE Rakoczy, IJ Constable Eye 9 (6), 763-771, 1995 | 504 | 1995 |
Differentiation of marrow stromal cells into photoreceptors in the rat eye A Kicic, WY Shen, AS Wilson, IJ Constable, T Robertson, PE Rakoczy Journal of Neuroscience 23 (21), 7742-7749, 2003 | 389 | 2003 |
Functional and structural recovery of the retina after gene therapy in the RPE65 null mutation dog K Narfström, ML Katz, R Bragadottir, M Seeliger, A Boulanger, ... Investigative ophthalmology & visual science 44 (4), 1663-1672, 2003 | 291 | 2003 |
Adenovirus and adeno-associated virus vectors CM Lai, YKY Lai, PE Rakoczy DNA and cell biology 21 (12), 895-913, 2002 | 274 | 2002 |
The use of synthetic polymers for delivery of therapeutic antisense oligodeoxynucleotides TV Chirila, PE Rakoczy, KL Garrett, X Lou, IJ Constable Biomaterials 23 (2), 321-342, 2002 | 271 | 2002 |
Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model PE Rakoczy, D Zhang, T Robertson, NL Barnett, J Papadimitriou, ... The American journal of pathology 161 (4), 1515-1524, 2002 | 215 | 2002 |
Gene therapy with recombinant adeno-associated vectors for neovascular age-related macular degeneration: 1 year follow-up of a phase 1 randomised clinical trial EP Rakoczy, CM Lai, AL Magno, ME Wikstrom, MA French, CM Pierce, ... The Lancet 386 (10011), 2395-2403, 2015 | 209 | 2015 |
Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: a long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity RJ Marano, I Toth, N Wimmer, M Brankov, PE Rakoczy Gene therapy 12 (21), 1544-1550, 2005 | 207 | 2005 |
Expression of cell adhesion molecules and vascular endothelial growth factor in experimental choroidal neovascularisation in the rat WY Shen, MJT Yu, CJ Barry, IJ Constable, PE Rakoczy British Journal of Ophthalmology 82 (9), 1063-1071, 1998 | 191 | 1998 |
Phase 2a randomized clinical trial: safety and post hoc analysis of subretinal rAAV. sFLT-1 for wet age-related macular degeneration IJ Constable, CM Pierce, CM Lai, AL Magno, MA Degli-Esposti, ... EBioMedicine 14, 168-175, 2016 | 177 | 2016 |
Pericytes derived from adipose-derived stem cells protect against retinal vasculopathy TA Mendel, EBD Clabough, DS Kao, TN Demidova-Rice, JT Durham, ... PLOS one 8 (5), e65691, 2013 | 177 | 2013 |
Long-term evaluation of AAV-mediated sFlt-1 gene therapy for ocular neovascularization in mice and monkeys CM Lai, WY Shen, M Brankov, YKY Lai, NL Barnett, SY Lee, IYS Yeo, ... Molecular Therapy 12 (4), 659-668, 2005 | 172 | 2005 |
Potential long-term inhibition of ocular neovascularisation by recombinant adeno-associated virus-mediated secretion gene therapy YKY Lai, WY Shen, M Brankov, CM Lai, IJ Constable, PE Rakoczy Gene therapy 9 (12), 804-813, 2002 | 164 | 2002 |
Role of VEGF in maintaining renal structure and function under normotensive and hypertensive conditions A Advani, DJ Kelly, SL Advani, AJ Cox, K Thai, Y Zhang, KE White, ... Proceedings of the National Academy of Sciences 104 (36), 14448-14453, 2007 | 156 | 2007 |
In Vivo Gene Therapy in Young and Adult RPE65−/− Dogs Produces Long-Term Visual Improvement K Narfström, ML Katz, M Ford, TM Redmond, E Rakoczy, R Bragadottir Journal of Heredity 94 (1), 31-37, 2003 | 152 | 2003 |
Inhibition of angiogenesis by adenovirus-mediated sFlt-1 expression in a rat model of corneal neovascularization CM Lai, M Brankov, T Zaknich, YKY Lai, WY Shen, IJ Constable, I Kovesdi, ... Human gene therapy 12 (10), 1299-1310, 2001 | 147 | 2001 |
Mouse models of age-related macular degeneration PE Rakoczy, JT Meaghan, S Nusinowitz, B Chang, JR Heckenlively Experimental eye research 82 (5), 741-752, 2006 | 136 | 2006 |
Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide RJ Marano, N Wimmer, PS Kearns, BG Thomas, I Toth, M Brankov, ... Experimental eye research 79 (4), 525-535, 2004 | 130 | 2004 |
Characterization of a mouse model of hyperglycemia and retinal neovascularization EP Rakoczy, ISA Rahman, N Binz, CR Li, NN Vagaja, M de Pinho, CM Lai The American journal of pathology 177 (5), 2659-2670, 2010 | 126 | 2010 |