From animal poisons and venoms to medicines: achievements, challenges and perspectives in drug discovery KCF Bordon, CT Cologna, EC Fornari-Baldo, EL Pinheiro-Júnior, ... Frontiers in pharmacology, 1132, 2020 | 206 | 2020 |
Minor snake venom proteins: Structure, function and potential applications J Boldrini-França, CT Cologna, MB Pucca, KCF Bordon, FG Amorim, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (4), 824-838, 2017 | 98 | 2017 |
Tityus serrulatus venom–A lethal cocktail MB Pucca, FA Cerni, ELP Junior, KCF Bordon, FG Amorim, FA Cordeiro, ... Toxicon 108, 272-284, 2015 | 88 | 2015 |
Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities J Boldrini-França, EL Pinheiro-Junior, S Peigneur, MB Pucca, FA Cerni, ... Scientific reports 10 (1), 1-11, 2020 | 38 | 2020 |
Kunitz-Type Peptides from the Sea Anemone Heteractis crispa Demonstrate Potassium Channel Blocking and Anti-Inflammatory Activities I Gladkikh, S Peigneur, O Sintsova, E Lopes Pinheiro-Junior, A Klimovich, ... Biomedicines 8 (11), 473, 2020 | 22 | 2020 |
LmrBPP9: a synthetic bradykinin-potentiating peptide from Lachesis muta rhombeata venom that inhibits the angiotensin-converting enzyme activity in vitro and reduces the blood … EL Pinheiro-Junior, J Boldrini-França, LMP de Campos Araújo, ... Peptides 102, 1-7, 2018 | 22 | 2018 |
Apamin structure and pharmacology revisited AI Kuzmenkov, S Peigneur, JA Nasburg, KS Mineev, MV Nikolaev, ... Frontiers in Pharmacology 13, 977440, 2022 | 19 | 2022 |
Functional and biological insights of rCollinein-1, a recombinant serine protease from Crotalus durissus collilineatus J Boldrini-França, EL Pinheiro-Junior, EC Arantes Journal of Venomous Animals and Toxins including Tropical Diseases 25, 2019 | 18 | 2019 |
Non-disulfide-bridged peptides from Tityus serrulatus venom: Evidence for proline-free ACE-inhibitors MB Pucca, FA Cerni, EL Pinheiro-Junior, KF Zoccal, KCF Bordon, ... Peptides 82, 44-51, 2016 | 18 | 2016 |
Microbial production of toxins from the scorpion venom: properties and applications FG Amorim, FA Cordeiro, EL Pinheiro-Júnior, J Boldrini-França, ... Applied microbiology and biotechnology 102 (15), 6319-6331, 2018 | 15 | 2018 |
Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone ML Mitchell, MA Hossain, F Lin, EL Pinheiro-Junior, S Peigneur, DCC Wai, ... Biomolecules 11 (12), 1785, 2021 | 13 | 2021 |
Towards toxin PEGylation: The example of rCollinein-1, a snake venom thrombin-like enzyme, as a PEGylated biopharmaceutical prototype EL Pinheiro-Junior, J Boldrini-França, AAS Takeda, TR Costa, S Peigneur, ... International Journal of Biological Macromolecules 190, 564-573, 2021 | 12 | 2021 |
Tuning scorpion toxin selectivity: switching from KV1. 1 to KV1. 3 AM Gigolaev, AI Kuzmenkov, S Peigneur, VM Tabakmakher, ... Frontiers in Pharmacology 11, 551725, 2020 | 10 | 2020 |
Design of New Potent and Selective Thiophene-Based KV1.3 Inhibitors and Their Potential for Anticancer Activity Š Gubič, LA Hendrickx, X Shi, Ž Toplak, Š Možina, KMV Theemsche, ... Cancers 14 (11), 2595, 2022 | 9 | 2022 |
Nicotinic Acetylcholine Receptors Are Novel Targets of APETx-like Toxins from the Sea Anemone Heteractis magnifica RS Kalina, IE Kasheverov, SG Koshelev, OV Sintsova, S Peigneur, ... Toxins 14 (10), 697, 2022 | 7 | 2022 |
A Tale of Toxin Promiscuity: The Versatile Pharmacological Effects of Hcr 1b-2 Sea Anemone Peptide on Voltage-Gated Ion Channels EL Pinheiro-Junior, R Kalina, I Gladkikh, E Leychenko, J Tytgat, ... Marine Drugs 20 (2), 147, 2022 | 7 | 2022 |
Pioneering Study on Rhopalurus crassicauda Scorpion Venom: Isolation and Characterization of the Major Toxin and Hyaluronidase CB Abreu, KCF Bordon, FA Cerni, IS Oliveira, C Balenzuela, ... Frontiers in immunology 11, 2011, 2020 | 7 | 2020 |
AsKC11, a Kunitz Peptide from Anemonia sulcata, Is a Novel Activator of G Protein-Coupled Inward-Rectifier Potassium Channels D An, EL Pinheiro-Junior, L Béress, I Gladkikh, E Leychenko, ... Marine Drugs 20 (2), 140, 2022 | 6 | 2022 |
Artificial Peptide Ligand of Potassium Channel KV 1.1 with High Selectivity VM Tabakmakher, AI Kuzmenkov, AM Gigolaev, EL Pinheiro-Junior, ... Journal of Evolutionary Biochemistry and Physiology 57 (2), 386-403, 2021 | 5 | 2021 |
New Diarylamine KV10. 1 Inhibitors and Their Anticancer Potential Š Gubič, Ž Toplak, X Shi, J Dernovšek, LA Hendrickx, EL Pinheiro-Junior, ... Pharmaceutics 14 (9), 1963, 2022 | 4 | 2022 |