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Ernesto Lopes Pinheiro-Junior
Ernesto Lopes Pinheiro-Junior
Johnson and Johnson Innovative Medicine
在 its.jnj.com 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
From animal poisons and venoms to medicines: achievements, challenges and perspectives in drug discovery
KCF Bordon, CT Cologna, EC Fornari-Baldo, EL Pinheiro-Júnior, ...
Frontiers in pharmacology, 1132, 2020
2062020
Minor snake venom proteins: Structure, function and potential applications
J Boldrini-França, CT Cologna, MB Pucca, KCF Bordon, FG Amorim, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (4), 824-838, 2017
982017
Tityus serrulatus venom–A lethal cocktail
MB Pucca, FA Cerni, ELP Junior, KCF Bordon, FG Amorim, FA Cordeiro, ...
Toxicon 108, 272-284, 2015
882015
Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities
J Boldrini-França, EL Pinheiro-Junior, S Peigneur, MB Pucca, FA Cerni, ...
Scientific reports 10 (1), 1-11, 2020
382020
Kunitz-Type Peptides from the Sea Anemone Heteractis crispa Demonstrate Potassium Channel Blocking and Anti-Inflammatory Activities
I Gladkikh, S Peigneur, O Sintsova, E Lopes Pinheiro-Junior, A Klimovich, ...
Biomedicines 8 (11), 473, 2020
222020
LmrBPP9: a synthetic bradykinin-potentiating peptide from Lachesis muta rhombeata venom that inhibits the angiotensin-converting enzyme activity in vitro and reduces the blood …
EL Pinheiro-Junior, J Boldrini-França, LMP de Campos Araújo, ...
Peptides 102, 1-7, 2018
222018
Apamin structure and pharmacology revisited
AI Kuzmenkov, S Peigneur, JA Nasburg, KS Mineev, MV Nikolaev, ...
Frontiers in Pharmacology 13, 977440, 2022
192022
Functional and biological insights of rCollinein-1, a recombinant serine protease from Crotalus durissus collilineatus
J Boldrini-França, EL Pinheiro-Junior, EC Arantes
Journal of Venomous Animals and Toxins including Tropical Diseases 25, 2019
182019
Non-disulfide-bridged peptides from Tityus serrulatus venom: Evidence for proline-free ACE-inhibitors
MB Pucca, FA Cerni, EL Pinheiro-Junior, KF Zoccal, KCF Bordon, ...
Peptides 82, 44-51, 2016
182016
Microbial production of toxins from the scorpion venom: properties and applications
FG Amorim, FA Cordeiro, EL Pinheiro-Júnior, J Boldrini-França, ...
Applied microbiology and biotechnology 102 (15), 6319-6331, 2018
152018
Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone
ML Mitchell, MA Hossain, F Lin, EL Pinheiro-Junior, S Peigneur, DCC Wai, ...
Biomolecules 11 (12), 1785, 2021
132021
Towards toxin PEGylation: The example of rCollinein-1, a snake venom thrombin-like enzyme, as a PEGylated biopharmaceutical prototype
EL Pinheiro-Junior, J Boldrini-França, AAS Takeda, TR Costa, S Peigneur, ...
International Journal of Biological Macromolecules 190, 564-573, 2021
122021
Tuning scorpion toxin selectivity: switching from KV1. 1 to KV1. 3
AM Gigolaev, AI Kuzmenkov, S Peigneur, VM Tabakmakher, ...
Frontiers in Pharmacology 11, 551725, 2020
102020
Design of New Potent and Selective Thiophene-Based KV1.3 Inhibitors and Their Potential for Anticancer Activity
Š Gubič, LA Hendrickx, X Shi, Ž Toplak, Š Možina, KMV Theemsche, ...
Cancers 14 (11), 2595, 2022
92022
Nicotinic Acetylcholine Receptors Are Novel Targets of APETx-like Toxins from the Sea Anemone Heteractis magnifica
RS Kalina, IE Kasheverov, SG Koshelev, OV Sintsova, S Peigneur, ...
Toxins 14 (10), 697, 2022
72022
A Tale of Toxin Promiscuity: The Versatile Pharmacological Effects of Hcr 1b-2 Sea Anemone Peptide on Voltage-Gated Ion Channels
EL Pinheiro-Junior, R Kalina, I Gladkikh, E Leychenko, J Tytgat, ...
Marine Drugs 20 (2), 147, 2022
72022
Pioneering Study on Rhopalurus crassicauda Scorpion Venom: Isolation and Characterization of the Major Toxin and Hyaluronidase
CB Abreu, KCF Bordon, FA Cerni, IS Oliveira, C Balenzuela, ...
Frontiers in immunology 11, 2011, 2020
72020
AsKC11, a Kunitz Peptide from Anemonia sulcata, Is a Novel Activator of G Protein-Coupled Inward-Rectifier Potassium Channels
D An, EL Pinheiro-Junior, L Béress, I Gladkikh, E Leychenko, ...
Marine Drugs 20 (2), 140, 2022
62022
Artificial Peptide Ligand of Potassium Channel KV 1.1 with High Selectivity
VM Tabakmakher, AI Kuzmenkov, AM Gigolaev, EL Pinheiro-Junior, ...
Journal of Evolutionary Biochemistry and Physiology 57 (2), 386-403, 2021
52021
New Diarylamine KV10. 1 Inhibitors and Their Anticancer Potential
Š Gubič, Ž Toplak, X Shi, J Dernovšek, LA Hendrickx, EL Pinheiro-Junior, ...
Pharmaceutics 14 (9), 1963, 2022
42022
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