Network pharmacology of cancer: From understanding of complex interactomes to the design of multi-target specific therapeutics from nature P Poornima, JD Kumar, Q Zhao, M Blunder, T Efferth Pharmacological Research 111, 290-302, 2016 | 176 | 2016 |
DNA, protein binding, cytotoxicity, cellular uptake and antibacterial activities of new palladium (ii) complexes of thiosemicarbazone ligands: effects of substitution on … P Kalaivani, R Prabhakaran, F Dallemer, P Poornima, E Vaishnavi, ... Metallomics 4 (1), 101-113, 2012 | 159 | 2012 |
Protective effect of gallic acid against lindane induced toxicity in experimental rats VV Padma, P Sowmya, TA Felix, R Baskaran, P Poornima Food and Chemical Toxicology 49 (4), 991-998, 2011 | 157 | 2011 |
Influence of terminal substitution on structural, DNA, Protein binding, anticancer and antibacterial activities of palladium (ii) complexes containing 3-methoxy salicylaldehyde … P Kalaivani, R Prabhakaran, E Ramachandran, F Dallemer, ... Dalton Transactions 41 (8), 2486-2499, 2012 | 147 | 2012 |
Neferine, an alkaloid from lotus seed embryo, inhibits human lung cancer cell growth by MAPK activation and cell cycle arrest P Poornima, CF Weng, VV Padma Biofactors 40 (1), 121-131, 2014 | 118 | 2014 |
Neferine from Nelumbo nucifera induces autophagy through the inhibition of PI3K/Akt/mTOR pathway and ROS hyper generation in A549 cells P Poornima, CF Weng, VV Padma Food chemistry 141 (4), 3598-3605, 2013 | 113 | 2013 |
Neferine induces reactive oxygen species mediated intrinsic pathway of apoptosis in HepG2 cells P Poornima, RS Quency, VV Padma Food chemistry 136 (2), 659-667, 2013 | 107 | 2013 |
Biological evaluation of new nickel (II) metallates: Synthesis, DNA/protein binding and mitochondrial mediated apoptosis in human lung cancer cells (A549) via ROS … P Kalaivani, S Saranya, P Poornima, R Prabhakaran, F Dallemer, ... European journal of medicinal chemistry 82, 584-599, 2014 | 102 | 2014 |
Versatile Coordination Behavior of Salicylaldehydethiosemicarbazone in Ruthenium (II) Carbonyl Complexes: Synthesis, Spectral, X-ray, Electrochemistry, DNA Binding … P Kalaivani, R Prabhakaran, P Poornima, F Dallemer, K Vijayalakshmi, ... Organometallics 31 (23), 8323-8332, 2012 | 99 | 2012 |
Evaluation of DNA binding, antioxidant and cytotoxic activity of mononuclear Co (III) complexes of 2-oxo-1, 2-dihydrobenzo [h] quinoline-3-carbaldehyde thiosemicarbazones E Ramachandran, SP Thomas, P Poornima, P Kalaivani, R Prabhakaran, ... European journal of medicinal chemistry 50, 405-415, 2012 | 90 | 2012 |
One pot synthesis of structurally different mono and dimeric Ni (ii) thiosemicarbazone complexes and N-arylation on a coordinated ligand: a comparative biological study R Prabhakaran, P Kalaivani, P Poornima, F Dallemer, G Paramaguru, ... Dalton Transactions 41 (31), 9323-9336, 2012 | 86 | 2012 |
Protective effect of neferine against isoproterenol-induced cardiac toxicity G Lalitha, P Poornima, A Archanah, VV Padma Cardiovascular toxicology 13 (2), 168-179, 2013 | 71 | 2013 |
Doxorubicin induced apoptosis was potentiated by neferine in human lung adenocarcima, A549 cells P Poornima, VB Kumar, CF Weng, VV Padma Food and Chemical Toxicology 68, 87-98, 2014 | 70 | 2014 |
Synthesis, structure, DNA/protein binding and in vitro cytotoxicity of new ruthenium metallates P Kalaivani, R Prabhakaran, E Vaishnavi, T Rueffer, H Lang, P Poornima, ... Inorganic Chemistry Frontiers 1 (4), 311-324, 2014 | 68 | 2014 |
Synthesis, X-ray crystal structure, DNA binding, antioxidant and cytotoxicity studies of Ni (II) and Pd (II) thiosemicarbazone complexes E Ramachandran, P Kalaivani, R Prabhakaran, NP Rath, S Brinda, ... Metallomics 4 (2), 218-227, 2012 | 65 | 2012 |
Neferine Potentiates the Antitumor Effect of Cisplatin in Human Lung Adenocarcinoma Cells Via a Mitochondria‐Mediated Apoptosis Pathway KS Sivalingam, P Paramasivan, CF Weng, V Viswanadha Journal of cellular biochemistry 118 (9), 2865-2876, 2017 | 62 | 2017 |
Maritoclax and dinaciclib inhibit MCL-1 activity and induce apoptosis in both a MCL-1-dependent and-independent manner S Varadarajan, P Poornima, M Milani, K Gowda, S Amin, HG Wang, ... Oncotarget 6 (14), 12668, 2015 | 60 | 2015 |
DNA binding, antioxidant, cytotoxicity (MTT, lactate dehydrogenase, NO), and cellular uptake studies of structurally different nickel (II) thiosemicarbazone complexes … R Prabhakaran, P Kalaivani, R Huang, P Poornima, V Vijaya Padma, ... JBIC Journal of Biological Inorganic Chemistry 18 (2), 233-247, 2013 | 60 | 2013 |
A comparative study on biologically and chemically synthesized silver nanoparticles induced Heat Shock Proteins on fresh water fish Oreochromis niloticus M Girilal, V Krishnakumar, P Poornima, AM Fayaz, PT Kalaichelvan Chemosphere 139, 461-468, 2015 | 58 | 2015 |
Quercetin attenuates lindane induced oxidative stress in wistar rats VV Padma, R Baskaran, RS Roopesh, P Poornima Molecular biology reports 39 (6), 6895-6905, 2012 | 58 | 2012 |