| Mapping genomic loci implicates genes and synaptic biology in schizophrenia V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ... Nature 604 (7906), 502-508, 2022 | 1402 | 2022 |
| Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology N Mullins, AJ Forstner, KS O’Connell, B Coombes, JRI Coleman, Z Qiao, ... Nature genetics 53 (6), 817-829, 2021 | 884 | 2021 |
| Rare coding variants in ten genes confer substantial risk for schizophrenia T Singh, T Poterba, D Curtis, H Akil, M Al Eissa, JD Barchas, N Bass, ... Nature 604 (7906), 509-516, 2022 | 493 | 2022 |
| Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors N Mullins, JE Kang, AI Campos, JRI Coleman, AC Edwards, H Galfalvy, ... Biological psychiatry 91 (3), 313-327, 2022 | 157 | 2022 |
| A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder J Duan, J Shi, A Fiorentino, C Leites, X Chen, W Moy, J Chen, ... The American Journal of Human Genetics 95 (6), 744-753, 2014 | 115 | 2014 |
| Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain I Alić, PA Goh, A Murray, E Portelius, E Gkanatsiou, G Gough, KY Mok, ... Molecular psychiatry 26 (10), 5766-5788, 2021 | 99 | 2021 |
| Analysis of ANK3 and CACNA1C variants identified in bipolar disorder whole genome sequence data A Fiorentino, NL O'Brien, DP Locke, A McQuillin, A Jarram, A Anjorin, ... Bipolar disorders 16 (6), 583-591, 2014 | 61 | 2014 |
| CACNA1C hypermethylation is associated with bipolar disorder A Starnawska, D Demontis, A Pen, A Hedemand, AL Nielsen, ... Translational Psychiatry 6 (6), e831-e831, 2016 | 54 | 2016 |
| The functional GRM3 Kozak sequence variant rs148754219 affects the risk of schizophrenia and alcohol dependence as well as bipolar disorder NL O’Brien, MJ Way, R Kandaswamy, A Fiorentino, SI Sharp, G Quadri, ... Psychiatric genetics 24 (6), 277-278, 2014 | 39 | 2014 |
| Characterisation of age and polarity at onset in bipolar disorder JL Kalman, LMO Loohuis, A Vreeker, A McQuillin, EA Stahl, D Ruderfer, ... The British Journal of Psychiatry 219 (6), 659-669, 2021 | 31 | 2021 |
| Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia G Leonenko, AL Richards, JT Walters, A Pocklington, K Chambert, ... American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 174 …, 2017 | 25 | 2017 |
| Whole-exome sequencing of individuals from an isolated population implicates rare risk variants in bipolar disorder F Lescai, TD Als, Q Li, M Nyegaard, G Andorsdottir, M Biskopstø, ... Translational psychiatry 7 (2), e1034-e1034, 2017 | 25 | 2017 |
| Exome sequence analysis and follow up genotyping implicates rare ULK1 variants to be involved in susceptibility to schizophrenia MM Al Eissa, A Fiorentino, SI Sharp, NL O'Brien, K Wolfe, G Giaroli, ... Annals of human genetics 82 (2), 88-92, 2018 | 23 | 2018 |
| Hypomethylation of FAM63B in bipolar disorder patients A Starnawska, D Demontis, A McQuillin, NL O’Brien, NH Staunstrup, ... Clinical epigenetics 8, 1-6, 2016 | 23 | 2016 |
| Modeling Down syndrome in cells: From stem cells to organoids G Gough, NL O'Brien, I Alic, PA Goh, YJ Yeap, J Groet, D Nizetic, ... Progress in Brain Research 251, 55-90, 2020 | 18 | 2020 |
| Rare variant analysis in multiply affected families, association studies and functional analysis suggest a role for the ITGΒ4 gene in schizophrenia and bipolar disorder NL O'Brien, A Fiorentino, D Curtis, C Rayner, C Petrosellini, M Al Eissa, ... Schizophrenia research 199, 181-188, 2018 | 15 | 2018 |
| Genetic variation in the miR‐708 gene and its binding targets in bipolar disorder A Fiorentino, NL O'Brien, SI Sharp, D Curtis, NJ Bass, A McQuillin Bipolar Disorders 18 (8), 650-656, 2016 | 15 | 2016 |
| Accelerated biological aging in people with Down syndrome with full and segmental trisomy 21 begins in childhood as revealed by immunoglobulin G glycosylation A Cindric, F Vuckovic, D Koschut, V Borelli, J Juric, M Pucic-Bakovic, ... | 6 | 2021 |
| The influence of regression models on genome-wide association studies of alcohol dependence: a comparison of binary and quantitative analyses W Li, JH Thygesen, NL O’Brien, M Heydtmann, I Smith, F Degenhardt, ... Psychiatric Genetics 31 (1), 13-20, 2021 | 6 | 2021 |
| Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels A Murray, G Gough, A Cindrić, F Vučković, D Koschut, V Borelli, ... EBioMedicine 94, 2023 | 4 | 2023 |
Andrew McQuillinUniversity College London在 ucl.ac.uk 的电子邮件经过验证
Andrew McQuillinUniversity College London在 ucl.ac.uk 的电子邮件经过验证
David CurtisUCL Genetics Institute在 ucl.ac.uk 的电子邮件经过验证
Sally I. SharpSenior Post-doctoral researcher